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BAG2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16207813 |
The activity of BAG-2 resembles that of the previously characterized Hsc70 cochaperone and CHIP inhibitor HspBP1. |
| 16169850 |
BAG2 binds to the carboxyl terminus of Hsp70-interacting protein (CHIP) and provides a cochaperone-dependent regulatory mechanism for preventing unregulated ubiquitylation of misfolded proteins by CHIP |
| 15271996 |
BAG2 was directly phosphorylated at serine 20 in vitro by MAPKAPK2 and MAPKAP2 is also required for phosphorylation of BAG2 in vivo. |
Recent Publications on BAG2: |  |
The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule.
Tau inclusions are a prominent feature of many neurodegenerative diseases... | 17th April, 2009
| Neuroscience Research Institute, University of California Santa Barbara,
| J Neurosci. 2009 Feb 18;29(7):2151-61.
DOI Direct Link |
Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry.
Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), an oncogenic fusion... | 20th February, 2009
| Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada.
| Am J Pathol. 2009 Feb;174(2):361-70. Epub 2009 Jan 8.
DOI Direct Link |
Induction of BAG2 protein during proteasome inhibitor-induced apoptosis in thyroid carcinoma cells.
BACKGROUND AND PURPOSE: Proteasome inhibitors exhibit cytotoxic against... | 17th January, 2009
| Department of Biochemistry & Molecular Biology, China Medical University,
| Br J Pharmacol. 2008 Nov;155(5):655-60. Epub 2008 Jul 28.
DOI Direct Link |
Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2.
Cochaperones are essential for Hsp70- and Hsc70-mediated folding of... | 1st January, 2009
| Department of Molecular Cardiology, Lerner Research Institute, NB50, 9500
| Nat Struct Mol Biol. 2008 Dec;15(12):1309-17. Epub 2008 Nov 23.
DOI Direct Link |
Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.
Epstein-Barr virus nuclear antigen 5 (EBNA5) is one of the first viral... | 22nd August, 2008
| Department of Clinical Chemistry and Transfusion Medicine, Institute of
| J Proteome Res. 2008 Jun;7(6):2309-19. Epub 2008 May 6.
DOI Direct Link |
→View more research publications. |
BAG2 results (if any) from reagent suppliers |
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BAG2 antibody (ab752) | Abcam
Goat polyclonal to BAG2. BAG proteins compete with Hip for binding to the Hsc70/ Hsp70 ATPase domain and promote substrate release. All the BAG proteins have ...
http://www.abcam.com/bag2-antibody-ab752.html...
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Bag-2 (L-21) Antibody sc-130969
rabbit polyclonal IgG, 100µg/ml; recommended for detection of Bag-2 of m, r, ... Bag-2 (L-21): sc-130969. Western blot analysis of Bag-2 expression in ...
http://www.scbt.com/datasheet-130969-bag-2-l-21-antibody.htm...
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BAG2 antibodies: Cancer > Invasion/microenvironment > Apoptosis ...
BAG2 antibodies. ... BAG2 antibody [EPR3567]. Flow Cyt, ICC, IP, WB, IHC-P. Images. Rabbit monoclonal. Reacts with: Hu. ab80596 · BAG2 antibody [EPR3568] ...
http://www.abcam.com/index.html?t=8933&pt=1&c=4240&ei=&mu=ra...
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Bag-2 (A-12) Antibody sc-101216
mouse monoclonal IgG1, 100 µg/ml; raised against recombinant Bag-2 of human origin ... Western blot analysis of Bag-2 expression in HeLa whole cell lysate. ...
http://www.scbt.com/datasheet-101216-bag-2-a-12-antibody.htm...
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Polyclonal Antibody to BAG-3
BAG-1S , BAG-1M (RAP46/HAP46), and BAG-1L, BAG2, BAG3 (CAIR-1; Bis,), BAG4 (SODD ), ... BAG-2 [212 aa; 24 kDa (Arndt et al. 2005)], BAG-3 (575 aa, 74 kDa), ...
http://www.imgenex.com/tds/IMG-5676.pdf...
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Bag Antibody / Bag Antibodies
Bag-2 (A-12) Antibody, sc-101216, mouse IgG1, FL (h), WB, IP, ELISA, human. Bag- 2 (C-20) Antibody, sc-68948, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, ...
http://www.scbt.com/ko/table-bag.html...
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Bag3 antibody (ab5898) | Abcam
The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high ...
http://www.abcam.com/bag3-antibody-ab5898.html...
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