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H2AFY
| Symbol: | H2AFY | | Name(s): | H2A histone family, member Y | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | H2A.y, H2A/y, H2AF12M, H2AFJ, MACROH2A1.1, mH2A1, macroH2A1.2 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18053270 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18227505 |
A phosphorylation site, S137ph, was identified in mH2A1;S137ph is enriched in mitosis. |
| 17570398 |
multiple short sequences dispersed along the macroH2A1 histone domain individually supported enrichment on the inactive X chromosome when introduced into H2A |
| 15897469 |
MACROH2A1 deposition is regulated by the CULLIN3/SPOP ligase complex and is actively involved in stable X inactivation. |
| 12082075 |
distributed during the maintainance phase of x inactivation throughout cell cycle |
| 17158748 |
A specific interaction between mH2A1.1 and PARP-1 was demonstrated and found to be associated with inactivation of PARP-1 enzymatic activity. |
Recent Publications on H2AFY: |  |
Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis.
The MYC oncogene has been implicated in the regulation of up to thousands... | 23rd July, 2008
| Department of Medicine, Division of Oncology, Stanford University School
| PLoS Genet. 2008 Jun 6;4(6):e1000090.
DOI Direct Link |
Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis.
BACKGROUND: Autism is a complex, heterogeneous, behaviorally-defined... | 15th February, 2008
| IntegraGen SA, 5 rue Henri Desbrueres, Genopole Campus 1, Genavenir 8,
| BMC Med Genet. 2007 Dec 6;8:74.
DOI Direct Link |
Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression.
The present study investigated mRNA expression profiles of bovine oocytes... | 14th December, 2007
| Department of Vertebrate Genomics, Max Planck Institute for Molecular
| Physiol Genomics. 2007 Oct 22;31(2):315-27. Epub 2007 Jun 26.
DOI Direct Link |
Splicing regulates NAD metabolite binding to histone macroH2A.
Histone macroH2A is a hallmark of mammalian heterochromatin. Here we show... | 27th August, 2005
| Gene Expression Unit, European Molecular Biology Laboratory,
| Nat Struct Mol Biol. 2005 Jul;12(7):624-5. Epub 2005 Jun 19.
DOI Direct Link |
H2AFY results (if any) from reagent suppliers | 
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HDAC2 peptide, HDAC2 (Ab-394) Antibody Blocking Peptide peptide
Subunit: Interacts with the non-histone region of H2AFY (By similarity). Part of the core histone deacetylase (HDAC) complex composed of HDAC1, HDAC2, ...
http://www.genwaybio.com/product_info.php?products_id=213340...
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MacroH2A1 siRNA (m) sc-149209
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, H2afy, 26914, 13 B1, Q9QZQ8 ...
http://www.scbt.com/ko/datasheet-149209-macroh2a1-sirna-m.ht...
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SPOP protein, Speckle-type POZ protein recombinant protein
In complex with CUL3, involved in ubiquitination of both PCGF4 and H2AFY. ... Part of a complex consisting of H2AFY, CUL3 and SPOP. Interacts with H2AFY ...
http://www.genwaybio.com/product_info.php?products_id=5035...
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MacroH2A1 siRNA (m) sc-149209
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. マウス, H2afy, 26914, 13 B1, Q9QZQ8 ...
http://www.scbt.com/ja/datasheet-149209-macroh2a1-sirna-m.ht...
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MacroH2A1 siRNA (h) sc-91790
... Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, H2AFY, 9555, 5q31.1, NM_001040158, NM_004893, NM_138609, NM_138610 · O75367 ...
http://www.scbt.com/ja/datasheet-91790-macroh2a1-sirna-h.htm...
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MacroH2 Antibody / MacroH2 Antibodies
NOMBRE DEL PRODUCTO, NUMERO DE CATALOGO, ISOTYPE, EPITOPE, APLICACIONES, SPECIES . MacroH2A (H-39) Anticuerpo, sc-67322, rabbit IgG, 144-182 (h), WB, IP, IF, ...
http://www.scbt.com/es/table-macroh2.html...
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MacroH2A1 siRNA (h) sc-91790
... 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, H2AFY, 9555, 5q31.1, NM_001040158, NM_004893, NM_138609, NM_138610 · O75367 ...
http://www.scbt.com/zh/datasheet-91790-macroh2a1-sirna-h.htm...
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