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GABBR2
| Symbol: | GABBR2 | | Name(s): | gamma-aminobutyric acid (GABA) B receptor, 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ36928, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 14966130 |
Association of the GABA(B)R1 with the GABA(A) receptor gamma2S subunit robustly promotes cell surface expression of GABA(B)R1 in the absence of GABA(B)R2, that is usually required for efficient trafficking of GABA(B)R1 to the cell surface. |
| 17145756 |
GABA(B) receptor stability and signaling can be modulated via GABA(B) receptor subunit 2 interactions with the PDZ scaffold protein Mupp1, which may contribute to cell-specific regulation of GABA(B) receptors in the central nervous system. |
| 14625043 |
Increased expression of GABA(B) receptor subtype 2 indicates augmented presynaptic inhibition of glutamate release as a possible protective mechanism in temporal lobe epilepsy. |
| 14961561 |
GABA(B) receptor subunit GABA(B)R2 is found on the same neurons and follows the same distribution patterns in the basal ganglia as the GABABR1 receptor subunit. |
| 14978362 |
The GABA(B) receptor may be present as a heterodimer with subunits of GABA(B1) and GABA(B2) in the human colon. |
| 16829628 |
Functional GABA(B) receptors are expressed in human airway smooth muscle cells |
Recent Publications on GABBR2: |  |
Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.
Previous studies have demonstrated that the gamma-aminobutyric acid type B... | 19th September, 2009
| Department of Psychiatry and Neurobehavioral Sciences, University of
| PLoS One. 2009 Sep 18;4(9):e7055.
DOI Direct Link |
Copy Number and Gene Expression Alterations in Radiation-Induced Papillary Thyroid Carcinoma from Chernobyl Pediatric Patients.
Background: Following exposure to radiation during the Chernobyl fallout... | 4th September, 2009
| 1 Roswell Park Cancer Institute , Department of Cancer Genetics, Buffalo,
| Thyroid. 2009 Sep 2.
DOI Direct Link |
Ischaemia differentially regulates GABA(B) receptor subunits in organotypic hippocampal slice cultures.
Reduced synaptic inhibition due to dysfunction of ionotropic GABA(A)... | 29th August, 2009
| Department of Anatomy, MRC Centre for Synaptic Plasticity, School of
| Neuropharmacology. 2009 Jun;56(8):1088-96. Epub 2009 Mar 28.
DOI Direct Link |
Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons.
Understanding the mechanisms that control synaptic efficacy through the... | 22nd July, 2009
| Physiology and Biophysics, Faculty of Medicine, Universidad de Chile,
| J Biol Chem. 2009 May 8;284(19):13077-85. Epub 2009 Mar 10.
DOI Direct Link |
Expression of GABA(B) receptors is altered in brains of subjects with autism.
Autism is a neurodevelopmental disorder that is often comorbid with... | 16th May, 2009
| Department of Psychiatry, Division of Neuroscience Research, University of
| Cerebellum. 2009 Mar;8(1):64-9.
DOI Direct Link |
→View more research publications. |
GABBR2 results (if any) from reagent suppliers | 
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p-GABAB R2 (Ser 783) Antibody sc-135695
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GABBR2, 9568, 9q22.33, O75899 ...
http://www.scbt.com/datasheet-135695-p-gabab-r2-ser-783-anti...
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G5293 Anti-phospho-GABAB Receptor (pSer892) R2 Subunit antibody ...
immunoblotting: 1:1000 using rat brain membranes. Gene Information, human ... GABBR2(9568). rat ... Gabbr2(83633). shipped in, dry ice. storage temp. −20°C
...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Antibodies to Neurotransmitter Receptors
G5293, Anti-phospho-GABAB Receptor (pSer892) R2 Subunit antibody produced in rabbit, (polyclonal), affinity isolated antibody, rat ... Gabbr2(83633) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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ATF-4 antibody, ATF4 (Ab-245) Antibody, Rabbit Polyclonal Antibody
Interacts with the C-terminal region of GABBR2 (By similarity). Binds DNA as a homo- or heterodimer. Interacts with the N-terminal region of CEP290. ...
http://www.genwaybio.com/product_info.php?products_id=210034...
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Anti-GABAB Receptor 2 (G9920) - Data Sheet
Anti-GABAB R2 antibody recognizes rat Gabbr2 (gene. ID: 83633) by immunoblotting . Rat, mouse and bovine are 100% homologous. ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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Anti-phospho-GABAB Receptor (pSer892) (G5293) - Data Sheet
(GABAB R2, GABABR2; GABBR2) is produced in rabbit using a synthetic phosphorylated peptide derived from the region of rat GABAB receptor R2 subunit
that is ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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