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CD40


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Symbol:CD40
Name(s):CD40 molecule, TNF receptor superfamily member 5
Type:protein-coding
Organism:Homo sapiens
Synonyms:Bp50, CDW40, MGC9013, TNFRSF5, p50
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18287517 Observational study of gene-disease association. (HuGE Navigator)
17999420 Activation of CD40 on cholangiocytes by activated macrophages provides a molecular mechanism to amplify chronic inflammation and bile duct destruction in liver disease.
14611700 Observational study of gene-disease association. (HuGE Navigator)
14695541 Observational study of gene-disease association. (HuGE Navigator)
15272925 Observational study of gene-disease association. (HuGE Navigator)
15301860 Observational study of genotype prevalence. (HuGE Navigator)
15367912 Observational study of gene-disease association. (HuGE Navigator)
16127217 Observational study of gene-disease association. (HuGE Navigator)
16279844 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16504636 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDmembrane-spanning 4-domains, subfamily A, member 1CD40 antigen isoform 1 precursor--Pubmed
HPRDmembrane-spanning 4-domains, subfamily A, member 1CD40 antigen isoform 1 precursor--Pubmed
HPRDCD40TRAF3 interacting protein 2 isoform 1--Pubmed
HPRDCD40 antigen isoform 1 precursorKu antigen, 80kDa--Pubmed
HPRDCD40 antigen isoform 1 precursorC6ORF5 protein--Pubmed
HPRDCD40 antigen isoform 1 precursorCD40 ligand--Pubmed
HPRDCD40 antigen isoform 1 precursorCD40 ligand--Pubmed
HPRDCD40 antigen isoform 1 precursorATP-dependent DNA helicase II, 70 kDa subunit--Pubmed
HPRDCD40 antigen isoform 1 precursorATP-dependent DNA helicase II, 70 kDa subunit--Pubmed
BINDCD40 antigen isoform 1 precursorTNF receptor-associated factor 3 isoform 1CD40 interacts with TRAF3.-Pubmed

Recent Publications on CD40:

Pubmed Logo
Pericardial Fat Volume Correlates With Inflammatory Markers: The Framingham Heart Study.
The objective of this study was to determine whether systemic inflammatory...
31st October, 2009
[1] National Heart, Lung, and Blood Institute's Framingham Heart Study, Obesity (Silver Spring). 2009 Oct 29.
DOI Direct Link
A comparative study of transfection methods for RNA interference in bone marrow-derived murine dendritic cells.
Selective gene silencing using RNA interference (RNAi) has been shown to...
31st October, 2009
Department of International Health, Immunology and Microbiology, Scand J Immunol. 2009 Nov;70(5):447-56.
DOI Direct Link
CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro.
INTRODUCTION: Aberrant signaling within and between B and T cells,...
30th October, 2009
Recherche et developpement, Hema-Quebec, Ingenierie cellulaire, 1070, Arch Immunol Ther Exp (Warsz). 2009 Oct 29.
DOI Direct Link
Expression of CD40 and CD40L in Gastric Cancer Tissue and Its Clinical Significance.
To study expression of CD40 and CD40L in gastric cancer tissue we assessed...
30th October, 2009
Department of Gastroenterology, First Affiliated Hospital of Soochow Int J Mol Sci. 2009 Sep 4;10(9):3900-17.
DOI Direct Link
Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects.
Phosphorothioate oligodeoxynucleotides can activate complement, and...
30th October, 2009
*Department of Oncology, Radiology and Clinical Immunology, Division of J Immunol. 2009 Oct 28.
DOI Direct Link

View more research publications.

Press Releases on CD40:

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Hard to Treat Diseases, Inc. (HTDS) Reports on Positive Research and HTDS MindUp Cancer Business Update 21st October, 2009 Hard to Treat Diseases

BELGRADE, SERBIA, Oct. 21 /PRNewswire-FirstCall/ - Hard to Treat Diseases, Inc. (HTDS:PK), http://www.htdsmedical.com announced that researchers in its

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology 31st March, 2009 PharmAthene, Inc.

ANNAPOLIS, Md., March 31 /PRNewswire-FirstCall/ --PharmAthene, Inc. (NYSE Amex: PIP), a biodefense company developing medical countermeasures against biological and chemical threats, announced

Emerging treatments for inflammatory bowel disease 1st June, 2001 Dailyupdates

Emerging treatments for inflammatory bowel disease

Feb,

Biotech Tracker: SGN-40 for Multiple Myeloma 1st January, 1970 Biotracker

Biotech Tracker: SGN-40 for

BioNews Results for CD40

: RSS Logo
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Establishment of an Immunoglobulin M Antibody-Forming Cell Response Model for Characterizing Immunotoxicity in
Toxicological Sciences:  Nov 14 2009 2:43AM Matching: cd40
Cancer Gene Therapy - Researchers from University of Crete, Division of Basic Sciences discuss findings in can
NewsRX:  Oct 31 2009 8:05PM Matching: cd40
Hard to Treat Diseases, Inc. (HTDS) Reports on Positive Research and HTDS MindUp Cancer Business Update
Red Orbit:  Oct 21 2009 2:20PM Matching: cd40
Hard to Treat Diseases, Inc. (HTDS) Reports on Positive Research and HTDS MindUp Cancer Business Update
Houston Business Journal:  Oct 21 2009 1:14PM Matching: cd40
Effects of 7,8-dihydro-8-oxo-deoxyguanosine on antigen challenge in ovalbumin-sensitized mice may be mediated by suppression of Rac
International Journal of Impotence Research:  Oct 21 2009 3:36PM Matching: cd40
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine.

Patents:

Patents logo
US Patent No.Title
7598353 Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
7604951 Method for identifying compounds that modulate RXR associated processes with IgE production
7604952 Detection and determination of the stages of coronary artery disease
7604955 Immunoglobulin E vaccines and methods of use thereof
7604989 Inhibition of apoptosis process and improvement of cell performance

View more patents.

CD40 results (if any) from reagent suppliers

Google CSE Logo
The Abcam catalog
CD40 antibodies. ... CD40 antibody [3/23]. Flow Cyt, ELISA, IHC-Fr. Rat monoclonal ... CD40 antibody [3/23] (Phycoerythrin). Flow Cyt. Rat monoclonal
...
http://www.abcam.com/index.html?t=140&pt=1&c=498...

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CD40 Antibody / CD40 Antibodies
CD40 Antibody / CD40 Antibodies. ... CD40 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-cd40.html...

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mouse CD40 antibody, Functional Gradeā„¢ Purified conjugate
eBioscience technical data sheet for product 16-0401 Functional Grade Purified anti-mouse CD40 1C10 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_16/16-...

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CD40 (C-20) Antibody sc-975
CD40: an upstream master switch for endothelial cell activation uncovered ... Western blot analysis of CD40 expression in non-transfected: sc-110760 (A) and
...
http://www.scbt.com/datasheet-975-cd40-c-20-antibody.html...

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APC Anti-human CD40 Antibody Anti-CD40 - BioLegend
APC Anti-human CD40 Antibody Anti-CD40 - CD40 is a 48 kD type I glycoprotein also known as BP50.
http://www.biolegend.com/apc-anti-human-cd40-antibody-2364.h...

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CD40 (T-20) Antibody sc-1731
See how others have used CD40 (T-20): sc-1731 antibody and or CD40 (T-20) ... Western blot analysis of CD40 expression in non-transfected: sc-110760 (A) and
...
http://www.scbt.com/datasheet-1731-cd40-t-20-antibody.html...

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LEAF Purified Anti-mouse CD40 Antibody Anti-CD40 - BioLegend
LEAF Purified Anti-mouse CD40 Antibody Anti-CD40 - CD40 is a 48Kd type I transmembrane glycoprotein, also known as Bp50. It is a member of the tumor ...
http://www.biolegend.com/leaf-purified-anti-mouse-cd40-antib...

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