Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

MAD2L1BP


Suggest Content
Advertise Here
Gene DB Home
Symbol:MAD2L1BP
Name(s):MAD2L1 binding protein
Type:protein-coding
Organism:Homo sapiens
Synonyms:CMT2, KIAA0110, MGC11282, RP1-261G23.6
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18022368 Data suggest that p31(comet)(CMT2) exploits the two-state behavior of Mad2 to block its activation by acting as an "anti-Mad2."
17934339 p31(comet) does not have an impact on the formation of aneuploidy and tetraploidy found in human hepatocellular carcinoma.
15257285 p31(comet, formerly known as Cmt2) counteracts the function of Mad2 and is required for the silencing of the spindle checkpoint

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDMAD2 mitotic arrest deficient like 1MAD2L1 binding protein isoform 2--Pubmed
HPRDMAD2-like 1MAD2L1 binding protein--Pubmed
BINDMAD2-like 1MAD2L1 binding protein isoform 2MAD2 interacts with CMT2.-Pubmed
HPRDthyroid hormone receptor interactor 13MAD2L1 binding protein isoform 2--Pubmed

Recent Publications on MAD2L1BP:

Pubmed Logo
Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders.
Since the early days of mitochondrial medicine, it has been clear that...
29th July, 2009
Department of Neurological Sciences, University of Bologna, Via Ugo Biochim Biophys Acta. 2009 May;1787(5):518-28. Epub 2009 Mar 5.
DOI Direct Link
p31comet Induces cellular senescence through p21 accumulation and Mad2 disruption.
Functional suppression of spindle checkpoint protein activity results in...
1st May, 2009
Laboratory of Radiation Molecular Cancer, Korea Institute of Radiological Mol Cancer Res. 2009 Mar;7(3):371-82. Epub 2009 Mar 10.
DOI Direct Link
Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B.
Four missense mutations, that target highly conserved amino acid residues...
13th August, 2008
Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali (DiSTeBA), Biochem Biophys Res Commun. 2008 Jul 25;372(2):283-7. Epub 2008 May 21.
DOI Direct Link
Checkpoint control: the journey continues.
Mad2 and p31(comet) are components of the spindle assembly checkpoint...
14th June, 2008
Research Institute of Molecular Pathology , Dr. Bohr-Gasse 7, A-1030 Curr Biol. 2008 Feb 26;18(4):R170-2.
DOI Direct Link
p31comet blocks Mad2 activation through structural mimicry.
The status of spindle checkpoint signaling depends on the balance of two...
26th February, 2008
Department of Pharmacology, The University of Texas Southwestern Medical Cell. 2007 Nov 16;131(4):744-55.
DOI Direct Link

View more research publications.

MAD2L1BP results (if any) from reagent suppliers

Google CSE Logo
MAD2L1BP Antibody / MAD2L1BP Antibodies
MAD2L1BP Antibody / MAD2L1BP Antibodies. ... MAD2L1BP specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-mad2l1bp.html...

Thumbshot
MAD2L1BP siRNA (m) sc-149212
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: MAD2L1BP ...
http://www.scbt.com/ko/datasheet-149212-mad2l1bp-sirna-m.htm...

Thumbshot
MAD2L1BP (4-RE23) Antibody sc-134381
MAD2L1BP (4-RE23) Antibody sc-134381 MAD2L1BP (4-RE23) Antibody sc-134381. ... Western blot analysis of MAD2L1BP expression in HeLa nuclear extract. ...
http://www.scbt.com/ko/datasheet-134381-mad2l1bp-4-re23-anti...

Thumbshot
MAD2L1BP (4-RE23) Antibody sc-134381
MAD2L1BP (4-RE23) 抗体 sc-134381 MAD2L1BP (4-RE23) Antibody sc-134381.
http://www.scbt.com/ja/datasheet-134381-mad2l1bp-4-re23-anti...

Thumbshot

Search Bioportfolio and other Life Science Sites for MAD2L1BP, or search for MAD2L1BP on BioPortfolio's antibody search engine.
This page has been viewed 73 times
Recent Search Terms used to find this page:
p31 comet antibody | p31-comet | MAD2L1 and radiation | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.