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AKAP12
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18199717 |
Hypermethylation of the AKAP12 promoter is associated esophageal carcinoma. |
| 17577780 |
The Gravin expression was found to be decreased in samples of acute leukaemia and was associated with an inferior overall survival. |
| 17442483 |
Results suggest that AKAP12 may play an important role in tumor growth suppression by inducing apoptosis with the regulation of multiple molecules in the cell cycle progression. |
| 12857743 |
gravin provides a dynamic platform for the localization for kinases during neuronal development |
| 17081159 |
We conclude that LPA-dependent increased level of cAMP in senescent human diploid fibroblasts is associated with increases in Gravin levels resulting in its increased binding with and activation of calcium-dependent PKC alpha/beta and AC4/6. |
| 15923193 |
AKAP12 localization is regulated by a hierarchy of targeting domains and the localization of AKAP12-assembled signaling complexes may be dynamically regulated |
| 14657015 |
AKAP250 acts as a scaffold that binds protein kinase A (PKA), protein kinase C and protein phosphatases, associating reversibly with the beta(2)-adrenergic receptor. |
| 16642035 |
Results suggest that gravin maintains a signaling complex that includes protein kinase A and phosphodiesterase 4D. |
| 15590635 |
AKAP12alpha belongs to a novel class of atypical SRF-dependent target genes |
| 15258566 |
AKAP12A may function as an important negative regulator of the survival pathway in human gastric cancer. | →View more information from publications. |
Recent Publications on AKAP12: |  |
Silencing of Cited2 and Akap12 genes in radiation-induced rat osteosarcomas.
We have previously studied genomic copy number changes and global gene... | 15th October, 2009
| LCE/iRCM/DSV/CEA, route du Panorama, BP 6, 92265 Fontenay-aux-Roses Cedex,
| Biochem Biophys Res Commun. 2009 Oct 13.
DOI Direct Link |
Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface.
The vascular network of the brain is formed by the invasion of vascular... | 15th October, 2009
| Neurovascular Coordination Research Center, College of Pharmacy, Seoul
| FEBS J. 2009 Sep;276(17):4622-35. Epub 2009 Jul 31.
DOI Direct Link |
Association of gene polymorphisms with chronic kidney disease in Japanese individuals.
Chronic kidney disease (CKD) is recognized as a risk factor not only for... | 3rd September, 2009
| Department of Cardiovascular Medicine, Inabe General Hospital, Inabe,
| Int J Mol Med. 2009 Oct;24(4):539-47.
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Gene expression profiling of alpha-radiation-induced rat osteosarcomas: identification of dysregulated genes involved in radiation-induced tumorigenesis of bone.
To better understand the molecular basis of radiation-induced osteosarcoma... | 23rd July, 2009
| Laboratoire de Cancerologie Experimentale, iRCM, DSV, CEA,
| Int J Cancer. 2009 Aug 1;125(3):612-20.
DOI Direct Link |
Light modulates the melanophore response to alpha-MSH in Xenopus laevis: An analysis of the signal transduction crosstalk mechanisms involved.
Melanin granule (melanosome) dispersion within Xenopus laevis melanophores... | 23rd June, 2009
| Department of Biology, University of Virginia, Charlotesville, VA
| Gen Comp Endocrinol. 2009 Jun 17.
DOI Direct Link |
→View more research publications. |
AKAP12 results (if any) from reagent suppliers | 
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AKAP12 antibody (ab10346) | Abcam
Sheep polyclonal to AKAP12. Gravin (also known as A Kinase Anchor Protein 12, AKAP12) was cloned from a cDNA expression library screened with serum, ...
http://www.abcam.com/AKAP12-antibody-ab10346.html...
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Antibodies to Scaffold Proteins
Akap12(83425), rat, IP, WB CL, pricing. T5942, Monoclonal Anti-14-3-3 θ/τ antibody produced in mouse, 3B9 (monoclonal), purified immunoglobulin ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Abgent - Phosphorylation Antibodies - Phosphorylation
AT1082a, AKAP10 monoclonal antibody (M04), ELISA,IHC-P,RNAi-Ab,S-ELISA,WB-Ce,WB- Re, H. AT1083a, AKAP12 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...
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All PKA | Abcam
AKAP12 antibody. WB. Images · Specific publication references. Goat polyclonal. Reacts with: Hu. ab23159 · AKAP12 peptide (1769-1782) ...
http://www.abcam.com/index.html?c=2124...
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AKAP 250 siRNA (m) sc-44761
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Akap12, 83397, 10 A1, Q9WTQ5 ...
http://www.scbt.com/datasheet-44761-akap-250-sirna-m.html...
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AZ Bethyl Laboratories - Welcome Bethyl Laboratories
AKAP12/Gravin · AKAP13/AKAP-Lbc · AKAP2 · AKAP8/AKAP95 · AKAP8L/HA95 · AKAP9/CG- NAP · AKAP95/AKAP8 · AKAP-Lbc/AKAP13 ...
http://www.bethyl.com/category/PCA_A-Z/Antibody/AAAAAAAABAAG...
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AKAP Antibody / AKAP Antibodies
AKAP El siRNA, el plásmido del sHRNA y los silenciadores especificos del gene de las partículas de Lentiviral del shRNA están también disponibles. ...
http://www.scbt.com/es/table-akap.html...
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