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CD44
| Symbol: | CD44 | | Name(s): | CD44 molecule (Indian blood group) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18214619 |
We believe that CD44s-mediated adhesion of malignant cells to other cells or to the extracellular matrix is responsible for the invasive features of biliary tract neoplasms, its aggressive progression, and its resistance to treatment. |
| 18092951 |
Significance of CD44 expression in transitional cell carcinoma of the bladder and explanaion for results on the relationship between CD44 expression and the biological behaviour of urothelial cells. |
| 18094716 |
The CD44 gene is silenced in NB4 acute promyelocytic leukemia cells by DNA methylation of a CpG island & underacetylation of histone H3 at the promoter. Brahma protein & phosphorylated RNA Pol II interact with the promoter region of CD44. |
| 16415175 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18162778 |
staining for TCL1, CD38, and CD44 are useful ancillary tests to identify B-cell tumors |
| 18193058 |
These findings establish that the HCELL glycoform of CD44 confers tropism to bone and unveil a readily translatable roadmap for programming cellular trafficking by chemical engineering of glycans on a distinct membrane glycoprotein. |
| 18199543 |
Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44. |
| 17945212 |
Results indicate that siRNA targeting a discrete sequence of human CD44 may provide a potential therapeutic option for colon cancer. |
| 17945213 |
These findings indicate that the secretion of soluble CD44 contributes to colon cancer growth in vitro, possibly as a decoy receptor. |
| 18155656 |
These are the first data to suggest a role for osteocytes and OPN in the recruitment of mesenchymal stem cells to aid in fracture repair. | →View more information from publications. |
Recent Publications on CD44: |  |
Characterisation of the activated liver progenitor cell niche, potential involvement of Wnt and Notch signalling.
BACKGROUND: Hepatic progenitor cells (HPCs) hold a great potential for... | 3rd November, 2009
| Belgium;
| Gut. 2009 Nov 1.
DOI Direct Link |
Generation of mesenchymal stromal cells from HOXB4-expressing human embryonic stem cells.
Background aims HOXB4 transcription factor plays an important role in... | 3rd November, 2009
| University of Wisconsin-Madison, School of Medicine and Public Health.
| Cytotherapy. 2009;11(6):716-25.
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An alternative method for the isolation of mesenchymal stromal cells derived from lipoaspirate samples.
Background aims Since initial methods were developed for isolating cells... | 3rd November, 2009
| APABCAM, Clementino Fraga Filho University Hospital, Federal University of
| Cytotherapy. 2009;11(6):706-15.
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Evidence linking CD44-positive cells and gemcitabine resistance in pancreatic cancer cells: Need for further substantiation.
Background aims Since initial methods were developed for isolating cells... | 31st October, 2009
| Clinical Cooperation Unit of Molecular Gastroenterology, German Cancer
| Int J Cancer. 2009 Oct 29.
DOI Direct Link |
Hyaluronan oligosaccharide treatment of chondrocytes stimulates expression of both HAS-2 and MMP-3, but by different signaling pathways.
OBJECTIVE: Small hyaluronan (HA) oligosaccharides displace HA from the... | 31st October, 2009
| Department of Biochemistry, Rush Medical College, Rush University Medical
| Osteoarthritis Cartilage. 2009 Oct 26.
DOI Direct Link |
→View more research publications. |
Press Releases on CD44:
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| ARIUS announces second quarter fiscal 2008 financial results |
11th July, 2008 |
ARIUS Research Inc. |
TORONTO, July 11 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX: ARI),
a biotechnology company discovering and developing the next wave of antibody
therapeutics, today announced its
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CD44 results (if any) from reagent suppliers | 
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