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CD63
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17827389 |
PrP(c) at the cell surface of cultured human erythroblasts is rapidly internalized through the endosomal pathway, where it colocalizes with the tetraspanin CD63. |
| 17522207 |
Data show that HIV-1 envelope glycoprotein (Env) and core protein (Gag) colocalize strongly with CD63 and CD81 and less strongly with CD9, and suggest that HIV-1 promotes virus assembly and cell-cell transfer by targeting these plasma membrane proteins. |
| 17624082 |
There is low expression of the proteins and mRNA of ME491/CD63 and integrin alpha5 in ovarian cancer. The lower the pathological differentiation is, the more significant the loss of expression is and the more likely metastasis is. |
| 14660791 |
CD63 serves as an adaptor protein that links its interaction partners to the endocytic machinery of the cell. |
| 17275019 |
In conclusion, using well-defined experimental conditions, the measurement of CD203c up-regulation on basophils in response to specific allergens is as reliable as CD63-BAT for the in vitro diagnosis of patients with IgE-mediated allergy. |
| 12610138 |
possible role in HIV-1 infections specific for macrophages |
| 15130945 |
results suggest that CD9, CD63, CD81, and CD82 could play a role in modulating the interactions between immature DCs and their environment, slowing their migratory ability. However, only CD63 would intervene in the internalization of complex antigens |
| 12036870 |
C-kit is physically associated with transmembrane 4 superfamily proteins CD9, CD63, and CD81, that may negatively modulate c-kit and thus regulate c-kit receptor sensitivity to SLF in hematopoietic progenitors. |
| 12871315 |
Upon platelet interaction with fibrinogen, cholesterol accumulated at the tips of filopodia and at the leading edge of spreading cells; cholesterol-rich raft aggregation was accompanied by concentration of c-Src and CD63 in these cell domains |
| 16918509 |
Chronic urticaria serum-induced CD63 expression assay performed on atopic whole blood by means of tricolor flow cytometry could be the most useful tool for identification of a subset of patients with autoimmune chronic urticaria. | →View more information from publications. |
Recent Publications on CD63: |  |
Usefulness of the CD63 basophil activation test in detecting Anisakis hypersensitivity in patients with chronic urticaria: diagnosis and follow-up.
Summary Background. The basophil activation test (BAT) has been recently... | 31st October, 2009
| Laboratory of Immunology and Allergology, Istituto Dermopatico
| Clin Exp Dermatol. 2009 Oct 23.
DOI Direct Link |
Midostaurin (PKC412) inhibits immunoglobulin E-dependent activation and mediator release in human blood basophils and mast cells.
BACKGROUND: KIT tyrosine kinase inhibitors (TKI), such as nilotinib or... | 29th October, 2009
| Department of Internal Medicine I, Division of Hematology and
| Clin Exp Allergy. 2009 Nov;39(11):1711-20.
DOI Direct Link |
Serial Change in Platelet Activation Markers With Aspirin and Clopidogrel After Acute Ischemic Stroke.
OBJECTIVES:: Antiplatelet drugs are widely used for secondary prevention... | 27th October, 2009
| *Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical
| Clin Neuropharmacol. 2009 Oct 22.
DOI Direct Link |
[Formation and function of Weibel-Palade bodies]
Weibel-Palade bodies (WPB) are specialized cigar-shaped secretory... | 13th October, 2009
| Institute of Genetics and Developmental Biology, Chinese Academy of
| Yi Chuan. 2009 Sep;31(9):882-8.
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ExoCarta: A compendium of exosomal proteins and RNA.
Exosomes, membrane microvesicles (40-100 nm) secreted by most cell types,... | 8th October, 2009
| Joint ProteomicS Laboratory, Ludwig Institute for Cancer Research and the
| Proteomics. 2009 Nov;9(21):4997-5000.
DOI Direct Link |
→View more research publications. |
Press Releases on CD63:
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| ARIUS announces second quarter fiscal 2008 financial results |
11th July, 2008 |
ARIUS Research Inc. |
TORONTO, July 11 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX: ARI),
a biotechnology company discovering and developing the next wave of antibody
therapeutics, today announced its
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