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EDEM1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17360537 |
the endoplasmic reticulum quality control vesicular transport pathway using EDEM1 does not involve the COPII exit sites |
| 15579471 |
EDEM1 is a soluble protein of the ER lumen in HEK293 cells |
| 16629899 |
These results indicate that EDEM may maintain the retrotranslocation competence of NHK by inhibiting aggregation so that unstable misfolded proteins can be accommodated by the dislocon for ERAD. |
| 12610306 |
EDEM was shown to extract misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle [EDEM] |
Recent Publications on EDEM1: |  |
Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans.
Exposure to sub-lethal levels of stress, or hormesis, was a means to... | 27th October, 2009
| Department of Life Science and Institute of Biotechnology, National Tsing
| Aging Cell. 2009 Aug;8(4):370-9. Epub 2009 Mar 16.
DOI Direct Link |
EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex.
Terminally misfolded or unassembled secretory proteins are retained in the... | 18th July, 2009
| Department of Biochemistry and Molecular Biology, University of
| Mol Cell. 2009 Jun 12;34(5):627-33.
DOI Direct Link |
The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I.
The secretory pathway provides a physical route through which only... | 12th June, 2009
| Department of Pathology, Baylor College of Medicine, Houston, TX 77030,
| J Cell Sci. 2009 Apr 1;122(Pt 7):976-84. Epub 2009 Mar 3.
DOI Direct Link |
Basal autophagy is involved in the degradation of the ERAD component EDEM1.
Little is known about the fate of machinery proteins of the protein... | 9th May, 2009
| Department of Pathology, University of Zurich, Switzerland.
| Cell Mol Life Sci. 2009 Apr;66(8):1434-45.
DOI Direct Link |
Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.
OBJECTIVE: Cytokines contribute to beta-cell destruction in type 1... | 1st January, 2009
| Diabetes and Obesity Research Program, Garvan Institute of Medical
| Diabetes. 2008 Nov;57(11):3034-44. Epub 2008 Jun 30.
DOI Direct Link |
→View more research publications. |
EDEM1 results (if any) from reagent suppliers | 
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Antibodies to Oxidative Stress Proteins
E8406, Anti-EDEM1 antibody produced in rabbit, affinity isolated antibody, mouse ... Pvalb(19293) human ... EDEM1(9695), human, mouse, IP, WB, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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EDEM (C-19) Antibody sc-27391
Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates ... EDEM1 reveals a quality control vesicular transport pathway out of the ...
http://www.scbt.com/ko/datasheet-27391-edem-c-19-antibody.ht...
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Anti-EDEM3 (E8906) - Data Sheet
cells, EDEM1 is localized to the ER, mainly as a soluble glycoprotein, and interacts with the ... glycoproteins as well, but in contrast to EDEM1, it ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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EDEM Antibody / EDEM Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. EDEM (C-19) Antibody, sc-27391, goat IgG, C-terminus (h), WB, IP, IF, ELISA, m, r, h ...
http://www.scbt.com/table-edem.html...
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Abcam antibodies and reagents product map
... DERL3 antibodies (3) · DPM3 antibodies (1) · EDEM1 antibodies (2) · EDEM3 antibodies (2) · EPM2AIP1 antibodies (2) · EPM2AIP1 proteins and peptides (1)
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http://www.abcam.com/index.html?cl=2105&pageconfig=productma...
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