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CD81
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12209363 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 17827389 |
In the plasma membrane, PrP(c) colocalizes with the tetraspanin CD81, sharing the same microdomain. |
| 17941058 |
CD81-independent routes of cell-cell transmission of hepatitis C virus exist. |
| 17407154 |
transferrin receptor and CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells |
| 17942559 |
CD81 is involved in Hepacivirus infection of human hepatocytes |
| 17507469 |
Results suggest that hepatitis C virus envelope glycoprotein E2 glycans modulate entry, CD81 binding, and neutralization by masking functionally important regions of E2 . |
| 17522207 |
Data show that HIV-1 envelope glycoprotein (Env) and core protein (Gag) colocalize strongly with CD63 and CD81 and less strongly with CD9, and suggest that HIV-1 promotes virus assembly and cell-cell transfer by targeting these plasma membrane proteins. |
| 15670777 |
These results suggest that the LEL has a more robust structure in the intact tetraspanin with regions outside the LEL contributing to CD81 dimerization. |
| 15767432 |
These findings suggest that engagement of CD81 decreases the signaling threshold required to initiate TCR/CD3-mediated induction of integrated HIV-1 proviral DNA in primary CD4+ T cells. |
| 15500552 |
binding with HCV E2 induces RANTES secretion and internalization of CCR5. | →View more information from publications. |
Recent Publications on CD81: |  |
Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility.
Glycosphingolipids NeuAcalpha3Galbeta4Glcbeta1Cer (GM3) and... | 31st October, 2009
| Division of Biomembrane Research, Pacific Northwest Research Institute,
| FEBS Lett. 2009 Oct 27.
DOI Direct Link |
Tetraspanin-induced death of myeloma cell lines is autophagic and involves increased UPR signalling.
BACKGROUND: Multiple myeloma (MM) therapy is hindered by the interaction... | 29th October, 2009
| Meir Medical Center, Kfar Saba, Israel.
| Br J Cancer. 2009 Oct 20;101(8):1402-9. Epub 2009 Sep 15.
DOI Direct Link |
Aberrant underexpression of CD81 in precursor B-cell acute lymphoblastic leukemia: utility in detection of minimal residual disease by flow cytometry.
We studied CD81 expression by flow cytometry (FC) on benign precursor B... | 23rd October, 2009
| Dept of Hematopathology, University of Texas M.D. Anderson Cancer Center,
| Am J Clin Pathol. 2009 Nov;132(5):692-8.
DOI Direct Link |
Regulation of NK cell trafficking by CD81.
NK cells, a heterogeneous sub-population of lymphocytes, are critically... | 16th October, 2009
| Department of Internal Medicine I, University of Bonn, Bonn, Germany.
| Eur J Immunol. 2009 Oct 14.
DOI Direct Link |
CD81 expression on CD19+ peripheral blood lymphocytes is associated with chronic HCV disease and increased risk for HCV infection: a putative role for inflammatory cytokines.
The level of CD81 cell surface expression, a cellular co-receptor for... | 16th October, 2009
| Department of Clinical Pathology and Microbiology, San Gallicano
| J Biol Regul Homeost Agents. 2009 Jul-Sep;23(3):155-64.
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→View more research publications. |
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