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CDC2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18356527 |
findings define a conserved signaling link between Cdk1 and FOXO1 that may have a key role in diverse biological processes, including the degeneration of postmitotic neurons |
| 17960875 |
Cdc2 and homeodomain-interacting protein kinase-2 (HIPK2) phosphorylate chromosomal high-mobility group A protein HMGA1 at the same site but show different site preferences. |
| 18003885 |
cdk phosphorylation of RUNX1 potentially couples stem/progenitor proliferation and lineage progression |
| 17636382 |
These findings suggest novel Cdk1/cyclin A phosphorylation sites, which appear to be associated with p53-independent cell death following etoposide treatment. |
| 18195732 |
the correct attachment of microtubules to kinetochores and efficient alignment of the chromosomes, most likely through localized phosphorylation of specific substrates by cyclin B1-CDK1. |
| 12648761 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16192727 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17159347 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17373700 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17498878 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | →View more information from publications. |
Recent Publications on CDC2: |  |
Cytotoxicity mechanisms of pyrazino[1,2-b]isoquinoline-4-ones and SAR studies.
The cytotoxicity showed by 1b, an interesting representant of the title... | 31st October, 2009
| Departamento de Quimica Organica y Farmaceutica, Facultad de Farmacia,
| Bioorg Med Chem. 2009 Oct 9.
DOI Direct Link |
2'-epi-2'-O-Acetylthevetin B extracted from seeds ofCerbera manghasL. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
2'-epi-2'-O-Acetylthevetin B (GHSC-74) is a cardiac glycoside isolated... | 31st October, 2009
| Department of Biochemistry and Molecular Biology, Second Military Medical
| Chem Biol Interact. 2009 Oct 26.
DOI Direct Link |
Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.
Cell death by the process of apoptosis plays important roles in... | 29th October, 2009
| Biomedical Research Institute, School of Medicine, College of Medicine,
| FEBS J. 2009 Nov;276(21):6063-73. Epub 2009 Sep 29.
DOI Direct Link |
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk).
A series of substituted 6-arylquinazolin-4-amines were prepared and... | 20th October, 2009
| NIH Chemical Genomics Center, National Human Genome Research Institute,
| Bioorg Med Chem Lett. 2009 Oct 3.
DOI Direct Link |
Clinical, pathological, proliferative and molecular responses associated with neoadjuvant aromatase inhibitor treatment in breast cancer.
Neoadjuvant treatment provides an exception setting in which to monitor... | 20th October, 2009
| Breast Unit Research Group, University of Edinburgh, Western General
| J Steroid Biochem Mol Biol. 2009 Oct 26.
DOI Direct Link |
→View more research publications. |
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