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GAB2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18272374 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17553421 |
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) |
| 15750601 |
We show that Gab2 has a crucial role in the differentiation of human progenitor cells into osteoclasts. |
| 15010462 |
Hck-mediated phosphorylation of Gab1 and Gab2 docking proteins in IL-6-induced proliferation and survival of multiple myeloma cells. |
| 14687710 |
over-expression of GRB2 and FLICE2 in RA synovium is caused by TNF-alpha inducibility differentially regulated in RA synoviocytes and provide potential pathogenic roles of these genes in the hyperplasia of the RA synovium. |
| 16253990 |
role for Gab2 in mammary tumorigenesis |
| 11830491 |
GAB2 is the limiting component of the GAB2-SHP2 complex, signaling Erk MAP kinase activation and terminal differentiation of K562 CML cells. |
| 12140767 |
The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer. |
| 15356145 |
Serine residue 623 of Gab2 is a phosphorylation target for MAP kinase (ERK), with demonstrated biochemical consequences on activation of ERK itself and on activation of STAT5. |
| 16736498 |
GAB2 is a novel target of 11q amplification in acute myeloid leukemia and myelodysplastic syndrome. | →View more information from publications. |
Recent Publications on GAB2: |  |
Focal amplification and oncogene dependency of GAB2 in breast cancer.
DNA amplifications in breast cancer are frequent on chromosome 11q, in... | 3rd November, 2009
| Department of Pathology, Stanford University, Stanford, CA, USA.
| Oncogene. 2009 Nov 2.
DOI Direct Link |
A unique domain in RANK is required for Gab2 and PLCgamma2 binding to establish osteoclastogenic signals.
TRAF6 is essential for osteoclastogenesis and for both RANK- and... | 23rd October, 2009
| Division of Cellular and Molecular Biology, Department of Cancer Biology,
| Genes Cells. 2009 Oct 20.
DOI Direct Link |
The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer.
Acquisition of independence from anchorage to the extracellular matrix is... | 20th October, 2009
| Department of Oncological Sciences and Laboratory of Functional Genomics,
| Oncogene. 2009 Oct 19.
DOI Direct Link |
GAB2 amplifications refine molecular classification of melanoma.
PURPOSE: Gain-of-function mutations in BRAF, NRAS, or KIT are associated... | 20th October, 2009
| Departments of Dermatology and Pathology and Department of Biostatistics,
| Clin Cancer Res. 2009 Jul 1;15(13):4288-91. Epub 2009 Jun 9.
DOI Direct Link |
Genome-wide association studies in Alzheimer's disease.
Genome-wide association studies (GWAS) have gained considerable momentum... | 8th October, 2009
| Neuropsychiatric Genetics Group, Max-Planck Institute for Molecular
| Hum Mol Genet. 2009 Oct 15;18(R2):R137-45.
DOI Direct Link |
→View more research publications. |
GAB2 results (if any) from reagent suppliers | 
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GAB2 antibody [EP369Y] (ab32365) | Abcam
Rabbit monoclonal [EP369Y] to GAB2. Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its
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http://www.abcam.com/GAB2-antibody-EP369Y-ab32365.html...
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Phospho-Gab2 (Ser159) Antibody #3884
Phospho-Gab2 (Ser159) Antibody detects endogenous levels of Gab2 only when phosphorylated at serine 159. This antibody does not cross-react with Gab1 or
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http://www.cellsignal.com/products/3884.html...
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GAB2 antibodies: Cancer > Signal transduction > Other | Abcam
GAB2 antibodies. ... GAB2 antibody [EP369Y]. Flow Cyt, WB, ICC/IF, IP. Images · Specific publication references. Rabbit monoclonal ...
http://www.abcam.com/index.html?t=146496&pt=1&c=4295&ei=&mu=...
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Phospho-Gab2 (Tyr452) Antibody #3881
Phospho-Gab2 (Tyr452) Antibody detects endogenous levels of Gab2 only when phosphorylated at tyrosine 452. The antibody weakly cross-reacts with ...
http://www.cellsignal.com/products/3881.html...
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Gab 2 siRNA (h) sc-40606
Click here for details. suitable control antibody: Gab 2 (H-200): sc-25498; sqRT -PCR Primer also available: Gab 2 (h)-PR: sc-40606-PR, 20 µl ...
http://www.scbt.com/datasheet-40606-gab-2-sirna-h.html...
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Phospho-Gab2 (Tyr452) Antibody
Tyr452 of human Gab2. Antibodies are purified by protein A ... or treated with Flt3 ligand using Phospho-Gab2 (Tyr452). Antibody. ...
http://www.cellsignal.com/pdf/3881.pdf...
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Gab Antibody / Gab Antibodies
Gab 2 (H-200) Antibody, sc-25498, rabbit IgG, 121-320 (h), WB, IP, IF, ELISA ... Gab 2 (M-19) Antibody, sc-9313, goat IgG, C-terminus (m), WB, IP, IF, ELISA ...
http://www.scbt.com/ko/table-gab.html...
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