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MAGI2


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Symbol:MAGI2
Name(s):membrane associated guanylate kinase, WW and PDZ domain containing 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:ACVRIP1, AIP1, ARIP1, MAGI-2, SSCAM
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17989107 Observational study of gene-disease association. (HuGE Navigator)
17880912 PTEN plays a critical role in MAGI-2-induced inhibition of cell migration and proliferation in human hepatocarcinoma cells

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDActivin A receptor, type IImembrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
HPRDbeta-1-adrenergic receptormembrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
HPRDcatenin, beta 1, 88kDamembrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
BINDHuman atrophin-1 mRNA, and translated productsmembrane associated guanylate kinase, WW and PDZ domain containing 2Atrophin-1 interacts with AIP1.-Pubmed
HPRDatrophin-1membrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
HPRDSMAD3membrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
HPRDphosphatase and tensin homologmembrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
HPRDmembrane associated guanylate kinase, WW and PDZ domain containing 2membrane associated guanylate kinase, WW and PDZ domain containing 2--Pubmed
HPRDmembrane associated guanylate kinase, WW and PDZ domain containing 2Down syndrome cell adhesion molecule like 1--Pubmed
HPRDmembrane associated guanylate kinase, WW and PDZ domain containing 2Down syndrome cell adhesion molecule like 1--Pubmed

Recent Publications on MAGI2:

Pubmed Logo
Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.
BACKGROUND: With the exception of APOE epsilon4 allele, the common genetic...
12th August, 2009
Department of Psychiatry and Human Behavior, University of California PLoS One. 2009 Aug 7;4(8):e6501.
DOI Direct Link
MAGI2 genetic variation and inflammatory bowel disease.
BACKGROUND: Despite recent advances the majority of inflammatory bowel...
13th March, 2009
Medical Genetics Institute & Inflammatory Bowel Disease Center, Inflamm Bowel Dis. 2009 Jan;15(1):75-83.
DOI Direct Link
No association between the protein tyrosine phosphatase, receptor-type, Z Polypeptide 1 (PTPRZ1) gene and schizophrenia in the Japanese population.
NRG1-ERBB signaling influences the risk for schizophrenia pathology. A...
18th November, 2008
Department of Psychiatry, Nagoya University Graduate School of Medicine, Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5;147B(7):1013-8.
DOI Direct Link
Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11.
Infantile spasms (IS) is the most severe and common form of epilepsy...
30th July, 2008
Program in Genetics & Genomic Biology and The Centre for Applied Genomics, Am J Hum Genet. 2008 Jul;83(1):106-11. Epub 2008 Jun 19.
DOI Direct Link
Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis.
BACKGROUND: Coeliac disease (gluten-sensitive enteropathy; GSE) and...
29th March, 2008
Genetics Department, University Medical Center Groningen, PO Box 30001, Gut. 2008 Apr;57(4):463-7. Epub 2007 Nov 7.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7595152 Detection of influenza virus
7595151 Methods and compositions for diagnosis and treatment of influenza
7538183 HPV vaccine comprising peptides from host cell proteins

MAGI2 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to MAGI-1, MAGI-2, MAGI-3/SLIPR
Antibodies to MAGI-1, MAGI-2, MAGI-3/SLIPR feature article is spotlighted at Sigma-Aldrich online. The MAGUK family of proteins, whose prototypic member is
...
http://www.sigmaaldrich.com/life-science/cell-biology/antibo...

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MAGI-2 (D-15) Antibody sc-11528
goat polyclonal IgG, 200 µg/ml; epitope mapping within an internal region of MAGI-2 of human origin; recommended for detection of MAGI-2 of human origin by
...
http://www.scbt.com/datasheet-11528-magi-2-d-15-antibody.htm...

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Anti-MAGI-2 antibody produced in rabbit (M2441) - Datasheet
MAGI-2 was first identified in rat, as a protein interacting with N-methyl-D- aspartate receptors ... respectively.10 MAGI-2 as well as MAGI-3, was shown to
...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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MAGI Antibody / MAGI Antibodies
MAGI-2 (V-15) Antibody, sc-11527, goat IgG, N-terminus (h), WB, IF, ... MAGI-2 ( C-17) Antibody, sc-11529, goat IgG, C-terminus (h), WB, IF, ELISA, human ...
http://www.scbt.com/table-magi.html...

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New Product Highlights
MAGI-2/rSCAM and Slipr/MAGI-3. Similar to other ... Antibodies to MAGI-1, MAGI-2 , Slipr/MAGI-3: Assemblers of multiprotein complexes. New Product Highlights ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/General_...

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Purified Anti-PTEN Antibody - BioLegend
PTEN has been shown to interact with phosphatidylinositol 3,4-bisphosphate, PtdIns(3,4,5)P(3), MAGI-1, MAGI-2, MAGI -3, hDLG, and MAST205. ...
http://www.biolegend.com/purified-anti-pten-antibody-2138.ht...

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MAGI-2 siRNA (m) sc-42003
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: MAGI-2 (m)-PR: sc-42003-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-42003-magi-2-sirna-m.html...

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