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KIF14


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Gene DB Home
Symbol:KIF14
Name(s):kinesin family member 14
Type:protein-coding
Organism:Homo sapiens
Synonyms:KIAA0042, MGC142302
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17962437 Overexpression of KIF14 was confirmed in primary human retinoblastoma and showed that patients with an older age at diagnosis express significantly higher levels of KIF14.
17545527 KIF14 is expressed most highly in squamous cell carcinoma, then in large-cell undifferentiated carcinoma, then adenocarcinoma
16431929 During cytokinesis, the localization of KIF14 and citron kinase to the central spindle and midbody is codependent, and they form a complex depending on the activation state of citron kinase.
16648480 RNA interference-mediated silencing of KIF14 disrupts cell cycle progression and induces cytokinesis failure.
17545527 KIF14 mRNA expression is prognostic for disease-free survival in non-small-cell lung cancer. Knockdown inhibits colony formation ability.
17099872 The KIF14 gene is amplified in retinoblastoma; likely an early genomic change in this cancer.
16570270 KIF14 is overexpressed in primary breast cancer; predicts disease-free and overall survival
15897902 Primary non-small-cell lung carcinoma overexpressing KIF14 showed a trend toward decreased survival.
15897902 Overexpressed in primary retinoblastoma and lung cancer, and in medulloblastoma and breast cancer cell lines. Low expression in normal adult tissue; highly expressed in fetal liver and thymus.

Recent Publications on KIF14:

Pubmed Logo
Consensus transcriptome signature of perineural invasion in pancreatic carcinoma.
Perineural invasion, the growth of tumor cells along nerves, is a key...
21st October, 2009
Department of General Surgery, Technische Universitat Munchen, Mol Cancer Ther. 2009 Jun;8(6):1494-504. Epub 2009 Jun 9.
DOI Direct Link
Gene expression profile analysis in laryngeal cancer by high-density oligonucleotide microarrays.
The assessment of gene expression profile in laryngeal cancer shall allow...
23rd July, 2009
ENT Department, Silesian Medical University, Katowice, Poland. J Physiol Pharmacol. 2009 May;60 Suppl 1:57-63.
Metal-proteinase ADAM12, kinesin 14 and checkpoint suppressor 1 as new molecular markers of laryngeal carcinoma.
The assessment of gene expression profile in laryngeal cancer allows...
18th July, 2009
ENT Department, Silesian Medical University, Francuska Str. 20-24, 40-270, Eur Arch Otorhinolaryngol. 2009 Oct;266(10):1501-7. Epub 2009 Jul 16.
DOI Direct Link
Three genetic developmental stages of papillary renal cell tumors: duplication of chromosome 1q marks fatal progression.
Papillary renal cell tumors (RCT) make up a cytomorphologically and...
3rd April, 2009
Laboratory of Molecular Oncology, Medical Faculty, Int J Cancer. 2009 May 1;124(9):2071-6.
DOI Direct Link
Diffusion and directed movement: in vitro motile properties of fission yeast kinesin-14 Pkl1.
Fission yeast Pkl1 is a kinesin-14A family member that is known to be...
14th March, 2009
Department of Life Sciences, Graduate School of Arts and Sciences, the J Biol Chem. 2008 Dec 26;283(52):36465-73. Epub 2008 Nov 4.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608739 Mitotic kinesin inhibitors
7307085 Mitotic kinesin inhibitors
7365178 Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis
7465746 Fluorinated 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP
7507858 Histone deacetylase inhibitors

View more patents.

KIF14 results (if any) from reagent suppliers

Google CSE Logo
KIF14 antibody (ab3747) | Abcam
Rabbit polyclonal to KIF14. KIF14 belongs to the kinesin-like protein family. It contains one FHA domain and one kinesin-motor domain.
http://www.abcam.com/KIF14-antibody-ab3747.html...

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KIF Antibody / KIF Antibodies
KIF14 (C-14) Antibody, sc-48559, goat IgG, Internal (h), WB, IF, ELISA, m, h .... KIF14 shRNA Plasmid (h): sc-60882-SH. KIF14 shRNA (h) ...
http://www.scbt.com/table-kif.html...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
Rabbit polyclonal to KIF14; KIAA0042; KIAA0042, IgG Polyclonal IP, WB, Source: Rabbit Reactivity: Human - Not yet tested in other species ...
https://www.genwaybio.com/all_polyclonal_antibodies.php?fl=K...

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KIF14 siRNA (m) sc-60883
Click here for details. suitable control antibody: KIF14 (K-20): sc-48562; sqRT- PCR Primer also available: KIF14 (m)-PR: sc-60883-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-60883-kif14-sirna-m.html...

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The Abcam catalog
KIF14 proteins and peptides. ... Image Abreview Publication. ab40360 · KIF14 peptide. IP, WB, ICC/IF, Dot. ab40361 · KIF14 peptide. IP, WB, ICC/IF, Dot ...
http://www.abcam.com/index.html?t=13942&pt=2&c=622...

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KIF14 (K-20) Antibody sc-48562
KIF14 (K-20) 抗体 sc-48562 KIF14 (K-20) Antibody sc-48562.
http://www.scbt.com/ja/datasheet-48562-kif14-k-20-antibody.h...

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Abcam antibodies and reagents product map
Dystrobrevin beta antibodies (2) · KIF14 antibodies (3) · KIF14 proteins and peptides (2) · KIF17 antibodies (1) · KIF3A antibodies (1) · KIF4A antibodies
...
http://www.abcam.com/index.html?c=2105...

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