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MAFB


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Gene DB Home
Symbol:MAFB
Name(s):v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
Type:protein-coding
Organism:Homo sapiens
Synonyms:KRML, MGC43127
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12542795 strong proliferative signals mediated by T-cell activation and interleukins (IL-4 and IL-12) downregulate the mafB messenger RNA transcript level when resting naive CD4+ T-helper cells enter the differentiation pathway in vitro.
12542796 Our data show that human monocytes, but not neutrophils, macrophages, dendritic or natural killer cells, downregulate the expression of Mac-1 after overnight exposure to surface-bound IgG.
15121870 novel role for MafB as a regulator of ERK-induced gene expression
16473681 Microarray analysis of Dupuytren's disease tissue has identified significant upregulated gene expression of MafB
15598817 high PU.1 activity favors dendritic cells at the expense of macrophage fate by inhibiting expression and activity of the macrophage factor MafB.
15135046 Low-density lipoprotein receptor-related protein intracellular domain co-localizes with MafB to the nucleus and negatively regulates its transcriptional activity
16456583 MafB is a key regulator of monocytopoiesis

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDtranscription factor MAFBtranscription factor MAFBMAFB interacts with MAFB-Pubmed

Recent Publications on MAFB:

Pubmed Logo
Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection.
Analyzing specialized cells in heterogeneous tissues is crucial for...
20th October, 2009
[1] Diabetes Branch, National Institute of Diabetes and Digestive and Nat Biotechnol. 2009 Oct 18.
DOI Direct Link
Developmental biology: Instructions writ in blood.
Analyzing specialized cells in heterogeneous tissues is crucial for...
7th October, 2009
Nature. 2009 Sep 10;461(7261):183-4.
DOI Direct Link
A vertebrate Polycomb response element governs segmentation of the posterior hindbrain.
Chromatin remodeling by Polycomb group (PcG) and trithorax group (trxG)...
1st October, 2009
Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, ON, M5G Cell. 2009 Sep 4;138(5):885-97.
DOI Direct Link
Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets.
BACKGROUND: Human peripheral blood monocytes (Mo) consist of subsets...
1st October, 2009
CRCHUM, Universite de Montreal, INSERM Unit 743, Montreal, Quebec, Canada. BMC Genomics. 2009 Aug 27;10:403.
DOI Direct Link
MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells.
While hematopoietic stem cell (HSC) self-renewal is well studied, it...
18th August, 2009
Centre d'Immunologie de Marseille-Luminy, Universite Aix-Marseille, Campus Cell. 2009 Jul 23;138(2):300-13.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5958671 Methods and compositions for regulating T cell subsets by modulating transcription factor activity
6579894 Prolines as antimicrobial agents
6586187 Methods for solid phase combinatorial synthesis of integrin inhibitors
6759233 Method of plasmid recovery and apparatus for doing so
6783942 Isolated polynucleotide associated with type II diabetes mellitus and methods of use thereof

View more patents.

MAFB results (if any) from reagent suppliers

Google CSE Logo
MafB (P-20) Antibody sc-10022
See how others have used MafB (P-20): sc-10022 antibody and or MafB (P-20) ... Western blot analysis of MafB expression in non-transfected: sc-117750 (A) ...
http://www.scbt.com/datasheet-10022-mafb-p-20-antibody.html...

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MafB antibodies: Chromatin and Nuclear Signaling > Transcription ...
MafB antibodies. ... MafB antibody. Flow Cyt, WB, ELISA, ICC/IF, IHC-P. Images · Customer Abreviews: 4 stars (out of 5) · Specific publication references ...
http://www.abcam.com/index.html?t=109903&pt=1&c=3579&ei=&mu=...

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Rabbit anti-c-Maf Antibody BL662, affinity purified
Detection of MafA, MafB and c-Maf by Western ... Binding of MafB and c-Maf within the enhancer ... purified rabbit anti-MafB antibody BL658 (Cat. No. ...
http://www.natutec.de/pdf_bethyl/A300-613A.pdf...

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Maf Antibody / Maf Antibodies
MafB (F-11) Antibody, sc-74521, mouse IgG2a, 111-210 (h), WB, IP, IF, ELISA, m, r, h ... MafB (P-20) Antibody, sc-10022, goat IgG, N-terminus (h), WB, IP, ...
http://www.scbt.com/table-maf.html...

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MAFA antibody - ChIP Grade (ab17976) | Abcam
Electrophoretic Mobility Shift of MafA, MafB and c-Maf. Samples: Nuclear extract (6 ug) from HeLa cells transfected with MafA, MafB or c-Maf expression ...
http://www.abcam.com/MAFA-antibody-ChIP-Grade-ab17976.html...

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MafB (h): 293 Lysate sc-111262
MafB (F-11): sc-74521. Western blot analysis of MafB expression in non- transfected: sc-110760 (A) and human MafB transfected: sc-111262 (B) 293 whole
cell ...
http://www.scbt.com/datasheet-111262-mafb-h-293-lysate.html...

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MafB - R&D Systems
MafB has been implicated in the regulation of hindbrain development. Heterodimers of MafK and p45 NF-E2, another bZIP factor, promote globin gene
expression ...
http://www.rndsystems.com/molecule_detail.aspx?m=3329...

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