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CDH1
| Symbol: | CDH1 | | Name(s): | cadherin 1, type 1, E-cadherin (epithelial) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | Arc-1, CD324, CDHE, ECAD, LCAM, UVO | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18065418 |
the CaR regulates cell survival and Ca(2+)(o)-induced differentiation in keratinocytes at least in part by activating the E-cadherin/PI3K pathway through a Src family tyrosine kinase-mediated signaling |
| 18197935 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 18342503 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 17685455 |
The E-cadherin gene methylation presence in tumors with lowest invasive and metastatic potential suggests the early involvement of this epigenetic event in the multistep progression of the oral carcinogenesis |
| 18174259 |
the APC has a novel role in UV-induced cell death; APC/CDH1 is regulated through proteolysis |
| 18223216 |
Noncohesive pancreatic cancers were characterized by the loss of E-cadherin protein expression. Promoter hypermethylation is a possible mechanism of E-cadherin gene silencing in a subset of these cancers. |
| 18245470 |
study describes activation of EGFR by mutant E-cadherin as a novel mechanism in tumor cells that explains the enhanced motility of tumor cells in the presence of an extracellular mutation of E-cadherin |
| 18235976 |
E-cadherin mutant missing N-glycans at Asn554, Asn566 and Asn618 failed to induce cell cycle arrest in G1 phase and to suppress cell proliferation in comparison with wild-type E-cadherin. |
| 11158177 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11705864 |
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) | →View more information from publications. |
Recent Publications on CDH1: |  |
Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis.
The anaphase-promoting complex/cyclosome (APC/C) is essential for... | 29th October, 2009
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| J Cell Sci. 2009 Oct 27.
DOI Direct Link |
Epithelial-mesenchymal transition with expression of SNAI1-induced chemoresistance in colorectal cancer.
BACKGROUND: Previous reports have demonstrated that SNAI1 plays a role in... | 29th October, 2009
| Department of Gastroenterological Surgery, Osaka University Graduate
| Biochem Biophys Res Commun. 2009 Oct 25.
DOI Direct Link |
[Hereditary non-polyposis colorectal cancer associated with hereditary gastric cancer. A case report.]
The information regarding the association of gastric cancer and type 2... | 28th October, 2009
| Medico pasante del Servicio Social, Instituto Nacional de Ciencias Medicas
| Rev Gastroenterol Mex. 2009 Jul-Sep;74(3):256-8.
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DNA damage checkpoint maintains CDH1 in an active state to inhibit anaphase progression.
DNA damage checkpoint prevents segregation of damaged chromosomes by... | 27th October, 2009
| Institute of Molecular and Cell Biology, A*STAR (Agency for Science,
| Dev Cell. 2009 Oct;17(4):541-51.
DOI Direct Link |
Assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens.
OBJECTIVE: DNA methylation is an early event in carcinogenesis. Testing... | 20th October, 2009
| Department of Pathology, Chonnam National University Medical School and
| Gynecol Oncol. 2009 Oct 14.
DOI Direct Link |
→View more research publications. |
CDH1 results (if any) from reagent suppliers | 
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CDH1 antibody [DH01 (DCS-266)] (ab3242) | Abcam
Cdh1 protein is a limiting, substrate-specific activator of anaphase-promoting complex (APC)-dependent proteolysis and it is required for the degradat...
http://www.abcam.com/CDH1-antibody-DH01-DCS-266-ab3242.html...
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C7855 Monoclonal Anti-Cdh1 antibody produced in mouse ~2 mg/mL ...
C7855 Monoclonal Anti-Cdh1 antibody produced in mouse ~2mg/mL, clone DCS-266, purified immunoglobulin, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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The Abcam catalog
CDH1 antibodies. ... CDH1 antibody [AR38.2]. WB, ELISA. Mouse monoclonal. Reacts with: Hu, Ms. ab3242 · CDH1 antibody [DH01 (DCS-266)]. IP, WB ...
http://www.abcam.com/index.html?t=11007&pt=1&c=1010...
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CDH1 Antibody
Specific antibody for the gene product of CDH1, the protein Cadherin 1. Validated for specificity by gene-silencing with siRNA followed by Western blot
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http://www.piercenet.com/products/Browse.cfm?fldID=E32F8415-...
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E Cadherin (CDH1) Antibody (C-term)
E Cadherin (CDH1) Antibody (C-term) Cell Function, E Cadherin (CDH1) Antibody (C -term) Stem Cell, E Cadherin (CDH1) Antibody (C-term) Cancer, E Cadherin ...
http://www.abgent.com/products/catalog_no/AP1477b...
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Protein and Antibody Solutions Provider - GenWay
Rabbit polyclonal to E Cadherin prediluted; 999; CDH1; 137215; P12830; Arc-1; CDHE; ... Rat monoclonal [DECMA - 1] to E Cadherin; 12550; Cdh1; AA960649; ...
http://www.genwaybio.com/advanced_search_result.php?so=c&igg...
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MONOCLONAL ANTI-CDH1 CLONE DCS-266 Purified Mouse Immunoglobulin ...
Cdh1. The product is useful in immunoblotting (a single or doublet band at approximately 50 kDa) ... Monoclonal antibody reacting specifically with Cdh1 is
...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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