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KCNE2


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Symbol:KCNE2
Name(s):potassium voltage-gated channel, Isk-related family, member 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:LQT5, LQT6, MGC138292, MIRP1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11289718 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
14661677 Observational study of gene-disease association. (HuGE Navigator)
14760488 Observational study of gene-disease association. (HuGE Navigator)
15051636 Observational study of gene-disease association. (HuGE Navigator)
15176425 Observational study of genotype prevalence. (HuGE Navigator)
15746444 Observational study of gene-disease association. (HuGE Navigator)
15840476 Observational study of gene-disease association. (HuGE Navigator)
16414944 Observational study of genotype prevalence and genetic testing. (HuGE Navigator)
16487223 Observational study of genotype prevalence. (HuGE Navigator)
16487842 Observational study of genetic testing. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDPotassium channel, voltage gated subfamily H, member 2potassium voltage-gated channel, Isk-related family, member 2--Pubmed
HPRDvoltage-gated potassium channel, subfamily H, member 2 isoform aPotassium channel, voltage gated, ISK related subfamily, member 2--Pubmed
HPRDPotassium channel, voltage gated, KQT like subfamily,1potassium voltage-gated channel, Isk-related family, member 2--Pubmed
HPRDpotassium voltage-gated channel, KQT-like subfamily precursor, member 1Potassium channel, voltage gated, ISK related subfamily, member 2--Pubmed

Recent Publications on KCNE2:

Pubmed Logo
Neonatal seizures and Long QT Syndrome: A cardiocerebral channelopathy?
Summary We identified a patient with electrophysiologically verified...
30th October, 2009
SA Pathology at Women's and Children's Hospital, North Adelaide, SA, Epilepsia. 2009 Oct 27.
DOI Direct Link
KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating.
Voltage-dependent potassium channels (Kv) play a crucial role in the...
24th September, 2009
Departament de Bioquimica i Biologia Molecular, Molecular Physiology J Cell Sci. 2009 Oct 15;122(Pt 20):3738-48. Epub 2009 Sep 22.
DOI Direct Link
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis.
Thyroid dysfunction is a global health concern, causing defects including...
22nd September, 2009
Greenberg Division of Cardiology, Department of Medicine and Department of Nat Med. 2009 Oct;15(10):1186-94. Epub 2009 Sep 20.
DOI Direct Link
Contribution of long-QT syndrome genetic variants in sudden infant death syndrome.
A cohort of 52 French unrelated infant cases who died unexpectedly before...
16th September, 2009
Laboratoire de Cardiogenetique Moleculaire, Centre de Biologie et Pediatr Cardiol. 2009 May;30(4):502-9. Epub 2009 Mar 26.
DOI Direct Link
Labour pains: giving birth to new mechanisms for the regulation of myometrial contractility.
BACKGROUND: Long QT syndrome (LQTS) is a potentially lethal, highly...
4th September, 2009
Department of Pharmacology, Loyola University Chicago, Maywood, IL 60153, J Physiol. 2009 May 15;587(Pt 10):2109-10.
DOI Direct Link

View more research publications.

BioNews Results for KCNE2

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Scientists find new genetic link between cardiac arrhythmias and thyroid dysfunction
Webindia123:  Sep 21 2009 1:46PM Matching: kcne2

Patents:

Patents logo
US Patent No.Title
7548780 Cell therapy and neural stimulation for cardiac repair
6849611 Implantation of biological pacemaker that is molecularly determined
6838243 Methods and compositions for polynucleotide analysis using generic capture sequences
6787309 Alterations in the long QT syndrome genes KVLQT1 and SCN5A and methods for detecting same
6653080 Loop probe hybridization assay for polynucleotide analysis

View more patents.

KCNE2 results (if any) from reagent suppliers

Google CSE Logo
K+ Channels in Cardiomyocytes
(immunoprecipitation) with KCNE2 in both healthy and diseased dogs ventricles.9 Anti KV11.1 ..... coimmunoprecipitation of ERG with KCNE2 using Anti- ...
http://www.alomone.com/system/UpLoadFiles/DGallery/Docs/K%20...

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MiRP1 (C-20) Antibody sc-16350
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, KCNE2, 9992, 21q22.11, NM_172201 ...
http://www.scbt.com/datasheet-16350-mirp1-c-20-antibody.html...

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MB-MN
KCNE2(9992) rat ... Kcne2(171138), rat, IHC, WB, pricing. M7273, Anti- Microtubule-Associated Proteins (MAPs) antibody produced in rabbit, (polyclonal)
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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MiRP Antibody / MiRP Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. MiRP1 (C-20) Antibody, sc-16350, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-mirp.html...

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Anti-Potassium Channel KCNE3 (MiRP2) (K0140) - Data Sheet
(IsK, MiNK), KCNE2 (MiRP1), KCNE4 (MiRP3) and. KCNE5 (MiRP4). KCNE1 is the founding member of the family and was initially believed to form a K+ channel
...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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05 HCN family the pacemaking channel.FH10
KCNE2. To date, four different HCN channels (HCN1-4), have been identified in mammals. When functionally expressed, they give rise to Ih-like ...
http://www.alomone.com/System/UpLoadFiles/DGallery/Docs/05HC...

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Complete Solutions for Ion Channels
... voltage-gated channel: Isk-related family: member 1, P3709. KCNE2, NM_172201 , potassium voltage-gated channel: Isk-related family: member 2, M3318 ...
http://www.sigmaaldrich.com/life-science/functional-genomics...

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