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Acetogenins

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Recent Publications on Acetogenins:

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Polyketides in insects: ecological role of these widespread chemicals and evolutionary aspects of their biogenesis.
Polyketides are known to be used by insects for pheromone communication...
9th July, 2008
Freie Universitat Berlin, Institute of Biology, Haderslebener Str. 9, Biol Rev Camb Philos Soc. 2008 May;83(2):209-26. Epub 2008 Apr 10.
DOI Direct Link
Paw Paw and Cancer: Annonaceous Acetogenins from Discovery to Commercial Products.
Extracts of paw paw ( Asimina triloba, Annonaceae) are among the most...
5th July, 2008
J Nat Prod. 2008 Jul 4;.
DOI Direct Link
Synthesis of hybrid acetogenins, alpha,beta-unsaturated-gamma-lactone-free nitrogen-containing heterocyclic analogues, and their cytotoxicity against human cancer cell lines.
A series of alpha,beta-unsaturated-gamma-lactone-free nitrogen-containing...
20th May, 2008
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Bioorg Med Chem Lett. 2008 Mar 1;18(5):1637-41. Epub 2008 Jan 19.
DOI Direct Link
Synthesis of pyranicin and its inhibitory action with bovine heart mitochondrial complex I.
Total synthesis of pyranicin was achieved using Cl2Pd(CH3CN)2-catalyzed...
16th May, 2008
Interdisciplinary Graduate School of Science and Technology, Shinshu Org Lett. 2008 Mar 6;10(5):717-20. Epub 2008 Feb 6.
DOI Direct Link
Dynamic function of the spacer region of acetogenins in the inhibition of bovine mitochondrial NADH-ubiquinone oxidoreductase (complex I).
Studies of the action mechanism of acetogenins, the most potent and...
15th May, 2008
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto Biochemistry. 2008 Jun 10;47(23):6260-6. Epub 2008 May 14.
DOI Direct Link

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Acetogenins Patents:

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US Patent No.Title
5780515 Benzoquinone and hydroquinone derivatives for use as insect feeding deterrents
6258841 Tubulin binding compounds (COBRA)
6326152 Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes
6329420 Tubulin binding compounds (COBRA)
6359000 Anticancer agent

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