Acetylesterase

In enzymology, an acetylesterase is an enzyme that catalyzes the chemical reaction:an acetic ester + H₂O $ightleftharpoons$ an alcohol + acetateThus, the two substrates of this enzyme are acetic ester and H₂O, whereas its two products are alcohol and acetate.This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is acetic-ester acetylhydrolase. Other names in common use include C-esterase , acetic ester hydrolase, chloroesterase, p-nitrophenyl acetate esterase, and Citrus acetylesterase. (From the Wikpedia article Acetylesterase.)

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Recent Publications on Acetylesterase:
Determination and Isolation of a Thioesterase from Passion Fruit (Passiflora edulis Sims) That Hydrolyzes Volatile Thioesters. Volatile organosulfur compounds (VOSCs) are high impact aroma chemicals...	11th July, 2008		J Agric Food Chem. 2008 Jul 10;. DOI Direct Link
Characterization of a new rhamnogalacturonan acetyl esterase from Bacillus halodurans C-125 with a new putative carbohydrate binding domain. BH1115 is a gene from Bacillus halodurans strain C-125 that hypothetically...	3rd July, 2008	Department of Biochemistry and Molecular Biology-A, Faculty of Biology,	J Bacteriol. 2008 Feb;190(4):1375-82. Epub 2007 Dec 14. DOI Direct Link
Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution. The hemagglutinin-esterases (HEs) are a family of viral envelope...	14th June, 2008	Crystal and Structural Chemistry, Bijvoet Center for Biomolecular	Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9065-9. Epub 2008 Jun 11. DOI Direct Link
An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum. The soft-rot fungus Penicillium purpurogenum secretes to the culture...	5th June, 2008	Departamento de Genetica Molecular y Microbiologia, Pontificia Universidad	J Comput Aided Mol Des. 2008 Jan;22(1):19-28. Epub 2007 Dec 1. DOI Direct Link
The ability to utilize mucin affects the regulation of virulence gene expression in Streptococcus pneumoniae. Streptococcus pneumoniae colonizes the mucin-rich environment of the...	3rd June, 2008		FEMS Microbiol Lett. 2008 Jan;278(2):231-5. Epub 2007 Dec 5. DOI Direct Link
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Acetylesterase Clinical Trials:
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	Myelodysplastic Syndromes

Acetylesterase Patents:
US Patent No.	Title
6184028	Polypeptides having pectin acetylesterase activity and nucleic acids encoding same
6465233	Nucleic acid molecule encoding a cephalosporin acetylesterase
6472205	Cytosolic forms for .beta.-lactamase and uses thereof
6485954	Enzyme with galactanase activity
6489279	Laundry and cleaning compositions containing xyloglucanase enzymes
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BioPortfolio Ltd. offers e-mail and postal lists for Acetylesterase scientists - we have details of around 50 individuals working on Acetylesterase .

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