Acrosome

In spermatozoa of many animals, the Acrosome is an organelle that develops over the anterior half of the sperm's head. It is a cap-like structure derived from the Golgi apparatus. Acrosome formation is completed during testicular maturation. In Eutherian mammals the acrosome contains digestive enzymes . These enzymes breakdown the outer membrane of the ovum called the zona pellucida, allowing the haploid nuclei in the sperm to join with the haploid nucleus found in the ova. (From the Wikpedia article Acrosome.)

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Recent Publications on Acrosome:
The "switching on" of mammalian spermatozoa: Molecular events involved in promotion and regulation of capacitation. Following the discovery of mammalian sperm capacitation and its...	13th November, 2009	Division of Reproduction and Endocrinology, School of Biomedical and	Mol Reprod Dev. 2009 Nov 11. DOI Direct Link
In Vitro Fertilization and Sperm Cryopreservation in the Black-Footed Cat (Felis nigripes) and Sand Cat (Felis margarita). Studies of in vitro fertilization (IVF) and sperm cryopreservation have...	13th November, 2009		Biol Reprod. 2009 Nov 11. DOI Direct Link
Use of the hypo-osmotic swelling test and aniline blue staining to improve the evaluation of seasonal sperm variation in native Spanish free-range poultry. The season may affect the values of fresh semen variables and therefore...	12th November, 2009	Departamento de Reproduccion Animal, and.	Poult Sci. 2009 Dec;88(12):2661-9. DOI Direct Link
Antifertility Characteristics of the N-terminal Region of Mouse Equatorial Segment Protein. To investigate antifertility characteristics of the equatorial segment...	10th November, 2009	Department of Histology and Embryology, Shanghai Jiao Tong University	Anat Rec (Hoboken). 2009 Nov 6. DOI Direct Link
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse. Polyamines are known to play important roles in the proliferation and...	7th November, 2009	TANAKA Project, Center for Advanced Science and Innovation, Osaka	PLoS Genet. 2009 Nov;5(11):e1000712. Epub 2009 Nov 6. DOI Direct Link
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Acrosome Clinical Trials:
Human Sperm Binding to Transgenic Mouse Eggs

Acrosome Patents:
US Patent No.	Title
7169548	Sperm cell processing and preservation systems
7262039	Polypeptide
7271243	Full-length human cDNAs encoding potentially secreted proteins
7273694	Method and apparatus for reducing pathogens in a biological sample
7276329	Method of sorting cells
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BioPortfolio Ltd. offers e-mail and postal lists for Acrosome scientists - we have details of around 558 individuals working on Acrosome .