Acrosome

In spermatozoa of many animals, the Acrosome is an organelle that develops over the anterior half of the sperm's head. It is a cap-like structure derived from the Golgi apparatus. Acrosome formation is completed during testicular maturation. In Eutherian mammals the acrosome contains digestive enzymes . These enzymes breakdown the outer membrane of the ovum called the zona pellucida, allowing the haploid nuclei in the sperm to join with the haploid nucleus found in the ova. (From the Wikpedia article Acrosome.)

Download PDF containing detailed information.

Recent Publications on Acrosome:
Effects of glycodelins on functional competence of spermatozoa. Glycodelin is a glycoprotein with 4 known glycoforms, namely glycodelin-S,...	28th October, 2009	Department of Obstetrics and Gynaecology, University of Hong Kong, Queen	J Reprod Immunol. 2009 Oct 24. DOI Direct Link
Transcription regulation in spermatogenesis. Spermatogenesis is a highly coordinated process in which diploid...	27th October, 2009	School of Biological Sciences, The University of Hong Kong, Pokfulam Road,	Adv Exp Med Biol. 2009;636:115-32. DOI Direct Link
The sperm proteasome during sperm capacitation and fertilization. The 26S proteasome is a multi-subunit protease specifically targeting...	27th October, 2009	Division of Animal Sciences and Department of Obstetrics, Gynecology &	J Reprod Immunol. 2009 Oct 21. DOI Direct Link
Characterization of Mithun (Bos frontalis) ejaculates and fertility of cryopreserved sperm. Technologies for conservation and propagation of genetic resources in the...	24th October, 2009	National Research Centre on Mithun (ICAR), Jharnapani, Medziphema,	Anim Reprod Sci. 2009 Sep 30. DOI Direct Link
Human zona pellucida glycoproteins: functional relevance during fertilization. The zona pellucida (ZP), a glycoproteinaceous matrix surrounding the...	24th October, 2009	Reproductive Cell Biology Laboratory, National Institute of Immunology,	J Reprod Immunol. 2009 Oct 20. DOI Direct Link
→View more research publications.

Acrosome Clinical Trials:
Human Sperm Binding to Transgenic Mouse Eggs

Acrosome Patents:
US Patent No.	Title
7169548	Sperm cell processing and preservation systems
7262039	Polypeptide
7271243	Full-length human cDNAs encoding potentially secreted proteins
7273694	Method and apparatus for reducing pathogens in a biological sample
7276329	Method of sorting cells
→View more patents.

BioPortfolio Ltd. offers e-mail and postal lists for Acrosome scientists - we have details of around 558 individuals working on Acrosome .