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Adenosine

Adenosine is a nucleoside composed of adenine attached to a ribose moiety via a β-N9-glycosidic bond.Adenosine plays an important role in biochemical processes, such as energy transfer - as adenosine triphosphate and adenosine diphosphate - as well as in signal transduction as cyclic adenosine monophosphate, cAMP. It is also an inhibitory neurotransmitter, believed to play a role in promoting sleep and suppressing arousal, with levels increasing with each hour an organism is awake. (From the Wikpedia article Adenosine.)

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Recent Publications on Adenosine:

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A new angiographic method to assess coronary flow reserve-Validation in humans.
Background: Coronary flow reserve (CFR) is defined as the ratio between...
20th November, 2009
Medizinische Klinik II, Klinikum Coburg gGmbH, Coburg, Germany. Catheter Cardiovasc Interv. 2009 Aug 31.
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Sex Steroids Inhibit Osmotic Swelling of Retinal Glial Cells.
Osmotic swelling of glial cells may contribute to the development of...
20th November, 2009
Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Neurochem Res. 2009 Nov 19.
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Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells.
Nuclear factor-kappaB (NF-kappaB) is involved in multiple aspects of...
20th November, 2009
[1] Department of Biology, University of Rome Tor Vergata, Via della Leukemia. 2009 Nov 19.
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Cyclic nucleotide signaling in polycystic kidney disease.
Increased levels of 3'-5'-cyclic adenosine monophosphate (cAMP) stimulate...
20th November, 2009
Division of Nephrology and Hypertension, Department of Medicine, Mayo Kidney Int. 2009 Nov 18.
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ADENOSINE A2A RECEPTOR SELECTIVE STIMULATION REDUCES SIGNALING PATHWAYS INVOLVED IN THE DEVELOPMENT OF INTESTINE ISCHEMIA AND REPERFUSION INJURY.
In the present study, we tested the efficacy of treatment with the...
20th November, 2009
*IRCCS Centro Neurolesi "Bonino-Pulejo", Messina, Italy section Shock. 2009 Nov 17.
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Press Releases About Adenosine:

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Reportlinker Adds Alzheimer's and Parkinson's Diseases - A Global Update of Market Trends & Opportunities 18th November, 2009 Reportlinker
NEW YORK, Nov. 18 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Alzheimer's and Parkinson's Diseases - A Global Update of Market
Video: New Analysis Supports Tolerability of Lexiscan(R) (regadenoson) Injection for Pharmacologic Myocardial Perfusion Imaging Studies 2nd October, 2009 Astellas Pharma US, Inc.
MINNEAPOLIS, Oct. 2 /PRNewswire/ -- A new analysis reaffirms that Lexiscan® (regadenoson) Injection, the first selective A2A adenosine receptor agonist approved for use as a pharmacologic stress
PeriCor Therapeutics Reports Positive Preclinical Results of GP531 at the European Heart Failure Congress in Nice 3rd June, 2009 PeriCor Therapeutics, Inc.
Adenosine Regulation with GP531 Improves the Heart's Pumping Function in Dogs with Advanced Chronic Heart Failure NEW YORK, June 3 /PRNewswire/ -- PeriCor Therapeutics, Inc. announced today that
Lotus Pharmaceuticals, Inc. Reports Strong 2008 Financial Results 22nd April, 2009 Lotus Pharmaceuticals, Inc.
BEIJING, April 22 /PRNewswire-Asia-FirstCall/ -- -- Revenues of $73.8 million -- Gross Profit of $33.4 million -- Net income of $12.8 million or $0.27 per diluted share Lotus
CV Therapeutics Announces Presentations at American Heart Association Scientific Sessions 2008 21st October, 2008 CV Therapeutics, Inc.
PALO ALTO, Calif., Oct. 21 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX) announced today that five clinical and preclinical abstracts have been accepted for presentation at the

BioNews Results for Adenosine:

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Role of Adenosine Signaling in Penile Erection and Erectile Disorders
MDLinx:  Nov 5 2009 10:25AM Matching: adenosine
Astex Therapeutics signs wide-ranging US cancer deal
Business Weekly UK:  Nov 3 2009 3:58PM Matching: adenosine
Head to Head Comparisons of Two Modalities of Adenosine Stress Echocardiography with Simultaneous SPECT
Medscape:  Nov 2 2009 10:05PM Matching: adenosine
Scientists at Karolinska University publish research in cytokines
Pharmacy Choice:  Oct 29 2009 11:03AM Matching: adenosine
Medical News: That '4 Hour Erection': New Discovery May Help Prevent A Complication Of Priapism
Medical News Today:  Oct 28 2009 11:05AM Matching: adenosine
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Adenosine Clinical Trials:

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Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia

Adenosine Patents:

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US Patent No.Title
7612196 siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
7615535 Inhibiting GS-FDH to modulate no bioactivity
7615536 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic
7615541 siRNA targeting TIE-2
7615546 Topical delivery system for phytosterols

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Companies working in the area of Adenosine from Bioportfolio's Biocorporate database :

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Medco Research Incorporated

Medco Research, Inc. is a pharmaceutical company dedicated to being a leader in the global commercialization of cardiovascular medicines and adenosine-receptor technologies leading to superior...
www.medcores.com/        View full profile
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Receptor Biology Incorporated

Receptor Biology Inc. produce cloned receptors for pharmacology studies and drug discovery, products include adenosine, cannabinoid, dopamine, muscarinic, serotonin, opoid, bradykinin, transporter,...
www.biolog.com/        View full profile
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Jinan Lekangxin Pharmacy Co.,Ltd

We are pleased to introduce our company, Jinan Lekangxin Pharmacy Co., Ltd as one of the leading producer and exporters of APIs(active pharmaceutical ingredients) and intermediates in China.Presently...
www.jnjz.com        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Adenosine scientists - we have details of around 18561 individuals working on Adenosine .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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