Saturday November 21 2009 | Biotechnology feed | All feeds
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AdenoviridaeAdenoviruses are medium-sized , nonenveloped icosahedral viruses containing double-stranded DNA. There are over 51 different serotypes in humans, which are responsible for 5–10% of upper respiratory infections in children, and many infections in adults as well. Viruses of the family Adenoviridae infect various species of animals, including humans. Adenoviruses were first isolated in human adenoids , from which the name is derived, and are classified as group I under the Baltimore classification scheme. Adenoviruses represent the largest nonenveloped viruses, because they are the maximum size able to be transported through the endosome . The virion also has a unique "spike" or fibre associated with each penton base of the capsid that aids in attachment to the host cell via the coxsackie-adenovirus receptor on the surface of the host cell. There are 51 immunologically distinct human adenovirus serotypes that can cause human infections ranging from respiratory disease , and conjunctivitis , to gastroenteritis . Adenoviruses are unusually stable to chemical or physical agents and adverse pH conditions, allowing for prolonged survival outside of the body and water. Adenoviruses are primarily spread via respiratory droplets, however they can also be spread by fecal routes as well.Most infections with adenovirus result in infections of the upper respiratory tract. Adenovirus infections often show up as conjunctivitis, tonsilitis , an ear infection, or croup. Adenoviruses can also cause gastroenteritis . A combination of conjunctivitis and tonsilitis is particularly common with adenovirus infections. Some children can develop adenovirus bronchiolitis or pneumonia, both of which can be severe. In babies, adenoviruses can also cause coughing fits that look almost exactly like whooping cough. Adenoviruses can also cause viral meningitis or encephalitis. Rarely, adenovirus can cause cystitis .Most people recover from adenovirus infections by themselves, but people with immunodeficiency sometimes die of adenovirus infections, and—rarely—even previously healthy people can die of these infections.Adenoviruses are often transmitted by coughed-out droplets, but can also be transmitted by contact with an infected person, or by virus particles left on objects such as towels and faucet handles. Some people with adenovirus gastroenteritis may shed the virus in their stools for months after getting over the symptoms. The virus can be passed from one person to another through some sexual practices, and through water in swimming pools that do not have enough chlorine in them. As with many other illnesses, good handwashing is one way to lessen the spread of adenoviruses from one person to another. Heat and bleach will kill adenoviruses on objects. As with all viruses, there are no antibiotics that help with an adenoviral infection, so treatment is largely directed at the symptoms . A doctor may give antibiotic eyedrops for conjunctivitis, since it takes a while to test to see if the eye infection is bacterial or viral and to help prevent secondary bacterial infections. In the past, US military recruits were vaccinated against two serotypes of adenotypes, with a corresponding decrease in illnesses caused by those serotypes. The vaccine is no longer manufactured, and there are currently no vaccines available to protect against the adenovirus. Good hygiene, including handwashing, is still the best way to avoid picking up the adenovirus from an infected person. (From the Wikpedia article Adenoviridae.) Download PDF containing detailed information.Image ResultsLoading...
BioPortfolio Ltd. offers e-mail and postal lists for Adenoviridae scientists - we have details of around 2095 individuals working on Adenoviridae . This page has been viewed 773 times Recent Search Terms used to find this page: how does adenoviridae spread | Adenoviridae Infection treatment | adenoviridae humans | where are adenoviridae viruses located | where are adenoviridae viruses located | Adenoviridae test | shed and spread capabilities of reconbinant adenovirus | Adenoviridae | conjunctivitis with Adenoviridae | . Browse BioPortfolio's InDepth service - alphabetically: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z or by Most Publications, recently searched for, or most viewed. Search for Adenoviridae across BioPortfolio, or for Adenoviridae Research Reports Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org | |||||||||||||||||||||||||||||||||||||||||||||||||||
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