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Alagille Syndrome

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Recent Publications on Alagille Syndrome:

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The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.
We previously determined that Notch2, and not Notch1 was required for...
17th November, 2009
Department of Developmental Biology, Washington University School of Dev Biol. 2009 Nov 12.
DOI Direct Link
The tetralogy of Fallot-associated G274D mutation impairs folding of the second epidermal growth factor repeat in Jagged-1.
Notch signaling controls spatial patterning and cell-fate decisions in all...
29th October, 2009
Protein Structure and Bioinformatics Group, International Centre for FEBS J. 2009 Nov;276(21):6247-57. Epub 2009 Sep 23.
DOI Direct Link
Novel human pathological mutations. Gene symbol: JAG1. Disease: Alagille syndrome.
Notch signaling controls spatial patterning and cell-fate decisions in all...
9th September, 2009
Lab. Genetica Molecolare, Ospedali Riuniti, Bergamo, Italy. Hum Genet. 2009 Aug;126(2):350-1.
Novel human pathological mutations. Gene symbol: JAG1. Disease: Alagille syndrome.
Notch signaling controls spatial patterning and cell-fate decisions in all...
9th September, 2009
Lab. Genetica Molecolare, Ospedali Riuniti, Bergamo, Italy. Hum Genet. 2009 Aug;126(2):350.
Novel human pathological mutations. Gene symbol: JAG1. Disease: Alagille syndrome.
Notch signaling controls spatial patterning and cell-fate decisions in all...
9th September, 2009
Lab. Genetica Molecolare, Ospedali Riuniti, Bergamo, Italy. Hum Genet. 2009 Aug;126(2):349-50.

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Press Releases About Alagille Syndrome:

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Merck Receives CHMP Positive Opinion for New Fertility Treatment, ELONVA(R) 20th November, 2009 Merck & Co., Inc.
WHITEHOUSE STATION, N.J., Nov. 20 /PRNewswire-FirstCall/ -- Merck & Co., Inc. today announced the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has
Viron reports positive Phase II data in Acute Coronary Syndromes (ACS) patients 18th November, 2009 Viron Therapeutics Inc.
VT-111 significantly reduces key cardiac enzymes at multiple time points after stent placement; Data presented at American Heart Association 2009 Scientific Sessions LONDON, ON, Nov. 18 /PRNewswire/
Oklahoma Medical Research Foundation Accelerates Discovery With Isilon IQ 18th November, 2009 Isilon Systems
SEATTLE, Nov. 18 /PRNewswire-FirstCall/ -- IsilonĀ® Systems (Nasdaq: ISLN) today announced that the Oklahoma Medical Research Foundation (OMRF), a nonprofit biomedical research institute, has
Albireo Announces Positive Clinical Data on A3309 in Patients with Chronic Idiopathic Constipation 18th November, 2009 Albireo
GOTHENBURG, Sweden, November 18 /PRNewswire/ -- Albireo today announced the completion of a phase 1b study showing a favorable tolerability and safety profile of A3309 in patients with chronic
Albireo Announces Positive Clinical Data on A3309 in Patients with Chronic Idiopathic Constipation 18th November, 2009
GOTHENBURG, Sweden, November 18 /PRNewswire/ -- Albireo today announced the completion of a phase 1b study showing a favourable tolerability and safety profile of A3309 in patients with chronic

BioNews Results for Alagille Syndrome:

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Swine flu update: Children from 6 months to 5 years invited
Irish Medical Times:  Nov 21 2009 4:50AM Matching: syndrome
China responds to underreporting claim
Reuters:  Nov 21 2009 12:32AM Matching: syndrome
Study Suggests Treatment for Down's Syndrome
Modern Medicine:  Nov 21 2009 12:05AM Matching: syndrome
Study Examines Challenges Of Diagnosing Neurofibromatosis Type 1-like Syndrome
Medical News Today:  Nov 21 2009 12:04AM Matching: syndrome
Study Finds Boosting Neurotransmitter Could Reverse Down Syndrome
MedIndia:  Nov 20 2009 5:13AM Matching: syndrome
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Alagille Syndrome Clinical Trials:

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Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

Alagille Syndrome Patents:

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US Patent No.Title
7014997 Chromosome structural abnormality localization with single copy probes
7262011 Screening of a novel hepatic syndrome and its uses
7273724 Polypeptide-human actin-binding protein 54 and a polynucleotide encoding the same
7279554 Notch receptor ligands and uses thereof
7332277 Methods for detection of genetic disorders

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BioPortfolio Ltd. offers e-mail and postal lists for Alagille Syndrome scientists - we have details of around 45 individuals working on Alagille Syndrome .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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