Ameloblastoma

Ameloblastoma is a rare, benign tumor of odontogenic epithelium much more commonly appearing in the mandible than the maxilla. While these tumors are rarely malignant or metastatic , and progress slowly, the resulting lesions can cause severe abnormalities of the face and jaw. Additionally, because abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder. Further, dentists caution that wide surgical excision is not invasive enough to adequately treat this disorder. (From the Wikpedia article Ameloblastoma.)

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Recent Publications on Ameloblastoma:
Radiographic interpretation of unilocular radiolucent mandibular lesions. The main goal of this study was to identify the main distinctive...	21st October, 2009	Oral Radiology Division, School of Dentistry, University of Sao Paulo,	Acta Odontol Latinoam. 2009;22(2):123-8.
Immortalization of ameloblastoma cells via reactivation of telomerase function: Phenotypic and molecular characteristics. Ameloblastoma (AM) is recognized as a benign tumour but locally invasive...	17th October, 2009	Department of Oral and maxillofacial Surgery, Guanghua School and Hospital	Oral Oncol. 2009 Oct 13. DOI Direct Link
The expression of nr0b1, the earliest gene in zebrafish tooth development, is a marker for human tooth and ameloblastoma formation. Zebrafish teeth develop on pharyngeal jaws in the 5th branchial arch, but...	15th October, 2009	Department of Pediatrics, David Geffen School of Medicine, UCLA, 10833 Le	Dev Genes Evol. 2009 Oct 14. DOI Direct Link
Ameloblastic carcinoma: An analysis of 6 cases with review of the literature. OBJECTIVES: The purpose of this study is to report 6 cases of ameloblastic...	6th October, 2009	Clinical lecturer, Department of Oral Pathology, Seoul, Korea.	Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Oct 1. DOI Direct Link
Ameloblastoma in children and adolescents. This study first reviewed the data of 37 patients aged 18 years and...	29th September, 2009	Department of Orthodontics, School of Stomatology, The Fourth Military	Br J Oral Maxillofac Surg. 2009 Sep 22. DOI Direct Link
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Ameloblastoma Patents:
US Patent No.	Title
5863726	Telomerase activity assays
6551774	Diagnostic methods for conditions associated with elevated cellular levels of telomerase activity
6596503	Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
6610839	Promoter for telomerase reverse transcriptase
6617110	Cells immortalized with telomerase reverse transcriptase for use in drug screening
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