Ameloblastoma

Ameloblastoma is a rare, benign tumor of odontogenic epithelium much more commonly appearing in the mandible than the maxilla. While these tumors are rarely malignant or metastatic , and progress slowly, the resulting lesions can cause severe abnormalities of the face and jaw. Additionally, because abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder. Further, dentists caution that wide surgical excision is not invasive enough to adequately treat this disorder. (From the Wikpedia article Ameloblastoma.)

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Recent Publications on Ameloblastoma:
Diffusion-Weighted MR Imaging of Ameloblastomas and Keratocystic Odontogenic Tumors: Differentiation by Apparent Diffusion Coefficients of Cystic Lesions. BACKGROUND AND PURPOSE: Ameloblastomas and keratocystic odontogenic tumors...	23rd August, 2008	Department of Radiology and Cancer Biology, Nagasaki University School of	AJNR Am J Neuroradiol. 2008 Aug 21. DOI Direct Link
[A case with malignant ameloblastoma of larynx] BACKGROUND AND PURPOSE: Ameloblastomas and keratocystic odontogenic tumors...	23rd August, 2008		Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008 May;43(5):389-90.
Usefulness of 18F-fluorodeoxyglucose positron emission tomography for detecting ameloblastoma, with special reference to glucose transporter-1 expression. The odontogenic tumors are an unusual group of lesions of the jaws derived...	22nd August, 2008	Department of Oral and Maxillofacial Surgery, Tokai University School of	J Oral Maxillofac Surg. 2008 Aug;66(8):1761-5. DOI Direct Link
Segmentally arranged basaloid follicular hamartomas with osseous, dental and cerebral anomalies: a distinct syndrome. A 39-year-old man presented with multiple basaloid follicular hamartomas...	19th August, 2008	Department of Dermatology, Philipp University of Marburg, Marburg,	Acta Derm Venereol. 2008;88(4):382-7. DOI Direct Link
Exophytic mass of lingual mandible. Peripheral ameloblastoma. A 39-year-old man presented with multiple basaloid follicular hamartomas...	8th August, 2008		Gen Dent. 2008 Jul-Aug;56(5):490, 492-3.
→View more research publications.

Ameloblastoma Patents:
US Patent No.	Title
5639613	Methods for cancer diagnosis and prognosis
5891639	Telomerase activity assays
5985266	Radiation enhanced therapy for tumors expressing a gene for viral thymidine kinase in the presence of a 5-halogengated pyrimidine
5989807	Detecting cancerous conditions by assaying for telomerase activity
6007989	Methods of screening for compounds that derepress or increase telomerase activity
→View more patents.

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