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AmyloidosisIn medicine, amyloidosis refers to a variety of conditions in which amyloid proteins are abnormally deposited in organs and/or tissues, causing disease. A protein is amyloid if, due to an alteration in its secondary structure, it takes on a particular insoluble form, called the beta-pleated sheet.Approximately 25 different proteins are known that can form amyloid in humans. Most of them are constituents of the plasma.Different amyloidoses can be systemic or organ-specific. Some are inherited, due to mutations in the precursor protein. Other, secondary forms are due to different diseases causing overabundant or abnormal protein production-such as with over production of immunoglobulin light chains in multiple myeloma , or with continuous overproduction of acute phase proteins in chronic inflammation . (From the Wikpedia article Amyloidosis.) Download PDF containing detailed information.
Recent Publications on Amyloidosis: |  |
Amyloidosis and Neurodegenerative Diseases: Current Treatments and New Pharmacological Options.
Most neurodegenerative diseases share several clinical, genetic and... | 20th November, 2009
| Academie Nationale de Medecine Paris, Paris, France.
| Pharmacology. 2009 Nov 18;85(1):1-17.
DOI Direct Link |
Marked shrinkage of amyloid lymphadenopathy after an intensive chemotherapy in a patient with IgM-associated AL amyloidosis.
A male patient with primary AL amyloidosis who had been suffering from... | 20th November, 2009
| Department of Medicine (Neurology and Rheumatologoy), Shinshu University
| Amyloid. 2009 Dec;16(4):243-245.
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Primary systemic amyloidosis and persistent pleural effusions.
Persistent pleural effusions are not common in patients with primary... | 20th November, 2009
| Alpert School of Medicine, Brown University, Providence, Rhode Island,
| Amyloid. 2009 Dec;16(4):239-242.
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Usefulness of labial salivary gland biopsy in familial amyloid polyneuropathy Portuguese type.
Background. The diagnosis of amyloidosis of all types is definitively made... | 20th November, 2009
| Department of Stomatology and Maxillofacial Surgery, Hospital de Santo
| Amyloid. 2009 Dec;16(4):232-238.
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Amyloid arthropathy mimicking seronegative rheumatoid arthritis in multiple myeloma: case reports and review of the literature.
We report two patients who suffered from symmetrical polyarthritis... | 20th November, 2009
| Department of Internal Medicine.
| Amyloid. 2009 Dec;16(4):226-231.
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→View more research publications. |
Press Releases About Amyloidosis:
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| Onyx Pharmaceuticals Announces Data Presentations Highlighting Carfilzomib and ONX 0803 at 51st American Society of Hematology Annual Meeting |
10th November, 2009 |
Onyx Pharmaceuticals, Inc. |
-- Abstract # 302
-- PX-171-004, an Ongoing Open-Label, Phase II Study of Single-Agent
Carfilzomib (CFZ) in Patients with Relapsed or Refractory Myeloma (MM);
Updated
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| One-Year Phase III Study Confirms Ilaris(R) Offers Long-Term Remission in Patients With CAPS, a Severe Lifelong Auto-Inflammatory Disease |
3rd June, 2009 |
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BASEL, Switzerland, June 3 /PRNewswire/ -- New results from a one-year Phase III study have confirmed
that the investigational biological therapy Ilaris(R) (canakinumab, formerly
ACZ885)[*] produced
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| ProteoTech to Present at 9th International Conference for Alzheimer's and Parkinson's Disease - Prague, Czech Republic, March 11-15, 2009 |
9th March, 2009 |
ProteoTech Inc. |
KIRKLAND, Wash., March 9 /PRNewswire/ -- ProteoTech Inc. announced today that both Dr. Alan D. Snow, Chairman, President & CSO, and Dr. Luke Esposito, Director of In Vitro Screening, will present
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| ProteoTech Receives Funding From The Michael J. Fox Foundation for Parkinson's Disease Research to Develop Tolls for Imaging Alpha-Synuclein Aggregation in Living Parkinson's Brain |
26th February, 2009 |
ProteoTech Inc. |
KIRKLAND, Wash., Feb 26 /PRNewswire/ -- ProteoTech Inc. announced today that it has been awarded a grant from The Michael J. Fox Foundation for Parkinson's Disease Research. In collaboration with
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| ProteoTech to Present at Rodman & Renshaw's 10th Annual Healthcare Conference |
10th November, 2008 |
ProteoTech, Inc. |
KIRKLAND, Wash., Nov. 10 /PRNewswire/ -- ProteoTech, Inc. announced today
that the Company Chief Executive Officer, Steve Runnels, will present an
overview of ProteoTech's drug development
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Companies working in the area of Amyloidosis from Bioportfolio's Biocorporate database : | |
| Company Name | |
Nephros, Inc. was founded in 1997 by Columbia University health professionals, scientists and engineers to improve the quality of life for the End Stage Renal Disease (ESRD) patient, while addressing...
www.nephros.com/ View full profile
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Neurochem Inc. is a dynamic, highly energized biopharmaceutical company with an exciting vision and future, located in the Parc scientifique et de haute technologie de Laval, in Quebec, Canada.
www.neurochem.com/ View full profile
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Company Description: ProteoTech Inc. is a world leader in research and development of new therapeutics derived from proteoglycan and amyloid technologies for the treatment of major human diseases....
www.proteotech.com/ View full profile
| | →View more Amyloidosis related companies. |
BioPortfolio Ltd. offers e-mail and postal lists for Amyloidosis scientists - we have details of around 1739 individuals working on Amyloidosis .
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
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