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Anthrax Anthrax is an acute disease in humans and animals that is caused by the bacterium Bacillus anthracis and is highly lethal in some forms. Anthrax is one of only a few bacteria that can form long-lived spores. When the bacteria’s life cycle is threatened by factors such as lack of food caused by their host dying or by a change of temperature, the bacteria turn themselves into more or less dormant spores to wait for another host to continue their life cycle.On breathing, ingesting or getting spores in a cut in the skin, a new host allows these spores to reactivate themselves and multiply in their new host very rapidly. The anthrax spores in soil are very tough and can live many decades and perhaps centuries and are known to occur on all continents except Antarctica. Anthrax most commonly occurs in wild and domestic grass-eating mammals who ingest or breathe in the spores while eating grass. Anthrax can also be caught by humans when they are exposed to dead infected pigs, eat tissue from infected animals, or are exposed to a high density of anthrax spores from an animal's fur, hide, or wool. Anthrax spores can be grown outside the body and used as a biological weapon. Anthrax cannot spread directly from human to human; but anthrax spores can be transported by human clothing, shoes etc. and if a person dies of anthrax their body can be a very dangerous source of anthrax spores. The word anthrax is the Greek word for coal, the germ's name is derived from anthrakitis, the Greek word for anthracite, in reference to the black skin lesions victims develop in a cutaneous skin infection. (From the Wikpedia article Anthrax.) Download PDF containing detailed information.
Recent Publications on Anthrax: |  |
Anthrax Lethal Toxin Induced Lysosomal Membrane Permeabilization and Cytosolic Cathepsin Release Is Nlrp1b/Nalp1b-Dependent.
NOD-like receptors (NLRs) are a group of cytoplasmic molecules that... | 20th November, 2009
| Department of Microbiology, Immunology & Molecular Genetics, University of
| PLoS One. 2009 Nov 18;4(11):e7913.
DOI Direct Link |
An anthrax lethal factor mutant that is defective at causing pyroptosis retains proapoptotic activity.
Anthrax lethal toxin triggers death in some cell types, such as... | 20th November, 2009
| Department of Laboratory Medicine and Pathobiology, University of Toronto,
| FEBS J. 2009 Nov 18.
DOI Direct Link |
Anthrax letters: personal exposure, building contamination, and effectiveness of immediate mitigation measures.
This report is the first detailed and quantitative study of potential... | 17th November, 2009
| Defence R&D Canada - Suffield, Medicine Hat, Alberta, Canada.
| J Occup Environ Hyg. 2010 Feb;7(2):71-9.
DOI Direct Link |
Detection of B. anthracis spores and vegetative cells with the same monoclonal antibodies.
Bacillus anthracis, the causative agent of anthrax disease, could be used... | 17th November, 2009
| State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese
| PLoS One. 2009 Nov 13;4(11):e7810.
DOI Direct Link |
[Production and characteristics of monoclonal antibodies to the diphtheria toxin.]
Monoclonal antibodies to the diphtheria toxin were produced without cross... | 17th November, 2009
| Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy
| Bioorg Khim. 2009 Sep-Oct;35(5):618-28.
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→View more research publications. |
Press Releases About Anthrax:
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| PharmAthene Reports Third Quarter 2009 Financial and Operational Results |
12th November, 2009 |
PharmAthene, Inc. |
-- RypVax(TM) - a recombinant dual antigen vaccine for plague
For more information about PharmAthene, please visit www.PharmAthene.com.
Statement on Cautionary Factors
Except for the
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| PharmAthene Executives Featured in Anthrax Pathogen Training Video for U.S. Department of Homeland Security |
5th October, 2009 |
PharmAthene, Inc. |
-- Protexia® - a novel bioscavenger for the prevention and treatment of
morbidity and mortality associated with exposure to chemical nerve
agents
For more information about
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| PharmAthene's 2nd Generation rPA Anthrax Vaccine, SparVax(TM), Completes FDA Regulatory Strategy Review |
9th July, 2009 |
PharmAthene, Inc. |
ANNAPOLIS, Md., July 9 /PRNewswire-FirstCall/ -- PharmAthene, Inc. (NYSE Amex: PIP), a biodefense company developing medical countermeasures against biological and chemical threats, today announced
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| Data Published in The New England Journal of Medicine Support Use of Raxibacumab (ABthrax(TM)) for the Treatment of Inhalation Anthrax |
9th July, 2009 |
Human Genome Sciences, Inc. |
ROCKVILLE, Md., July 9 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI) today announced publication by The New England Journal of Medicine of the results of two pivotal animal
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| Independent U.S. Study Confirms Veritide's Ceeker(TM) Handheld Device Detects Anthrax With Outstanding Accuracy and Reliability |
25th June, 2009 |
Veritide Ltd. |
--In Testing Conducted by a U.S. Research Institute, Ceeker Correctly Detected Anthrax 100% of the Time--
--Provides First Responders with a Simple and Reliable Tool to Help Quickly Distinguish
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Companies working in the area of Anthrax from Bioportfolio's Biocorporate database : | |
| Company Name | |
ASCIInc is a premiere Healthcare and Life Science Company that understands the labyrinth of possibilities involving immunization and vaccination programs utilizes an intelligent eidetic system...
www.asciinc.com View full profile
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Emergent BioSolutions Inc. is a biopharmaceutical company dedicated to one simple mission—to protect life. We develop, manufacture and commercialize immunobiotics, consisting of vaccines and...
www.antexbio.com/default.aspx View full profile
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Cangene is a world leader in the development , manufacture, and commercialization of specialty hyperimmune plasma and biotechnology products. Cangene has built two decades of success with the life...
www.cangene.com/ View full profile
| | →View more Anthrax related companies. |
BioPortfolio Ltd. offers e-mail and postal lists for Anthrax scientists - we have details of around 420 individuals working on Anthrax .
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
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