Arachnoiditis

Arachnoiditis is a neuropathic disease caused by the inflammation of the arachnoid, one of the membranes that surround and protect the nerves of the central nervous system, including the brain and spinal cord. The arachnoid can become inflamed because of an irritation from chemicals, infection from bacteria or viruses, as the result of direct injury to the spine, chronic compression of spinal nerves, or complications from spinal surgery or other invasive spinal procedures. Inflammation can sometimes lead to the formation of scar tissue and adhesions which can cause the spinal nerves to "stick" together. (From the Wikpedia article Arachnoiditis.)

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Recent Publications on Arachnoiditis:
Complications following large-volume epidural blood patches for postdural puncture headache. Lumbar subdural hematoma and arachnoiditis: initial cause or final effect? Significant complications following large-volume epidural blood patches...	18th November, 2009	Department of Anesthesiology, Critical Care, and Pain Management, Beth	J Clin Anesth. 2009 Aug;21(5):355-9. Epub 2009 Aug 22. DOI Direct Link
[Lumbosacral arachnoiditis secondary to a lumboperitoneal shunt] Pathologic processes within the cerebellopontine angle (CPA) may present...	28th October, 2009	Servicio de Neurocirugia, Complejo Hospitalario Universitario de Santiago	Rev Neurol. 2009 Nov 16-30;49(10):547-8.
[Arachnoiditis and tuberculuos cortical encephalitis in an HIV+ patient] HIV infection is a major risk factor for tuberculosis. We describe the...	1st October, 2009	Servicios de Medicina Interna, Division de Medicina Interna, Hospital	Gac Med Mex. 2009 May-Jun;145(3):239-40.
Pharmacokinetics and safety of intrathecal liposomal cytarabine in children aged <3 years. BACKGROUND AND OBJECTIVE: Liposomal cytarabine (DepoCyte) is a...	11th September, 2009	Department of Paediatrics, Medical University of Vienna, Vienna, Austria.	Clin Pharmacokinet. 2009;48(4):265-71. doi:
The neuraxial effects of intraspinal amitriptyline at low concentrations. BACKGROUND: As a result of amitriptyline's vast array of actions, it could...	10th September, 2009	Department of Anesthesiology, Sao Paulo State University-UNESP,	Anesth Analg. 2009 Sep;109(3):965-71. DOI Direct Link
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Press Releases About Arachnoiditis:
AIMSPRO is Awarded TGA Orphan Status for the Treatment of Amyotrophic Lateral Sclerosis	1st June, 2009		LONDON, June 1 /PRNewswire/ -- Privately owned UK biotech company Daval International Limited (http://www.davalinternational.com) has been informed by Australia's Therapeutic Goods Administration

Arachnoiditis Clinical Trials:
Use of Thalidomide in Patients With Arachnoiditis

Arachnoiditis Patents:
US Patent No.	Title
7404969	Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
7462622	Pyrrolo[2, 3-d] pyrimidine derivatives as corticotropin releasing factor antagonists
7462717	C6-and C9-substituted chromeno[4,3-c]isoxazoline derivatives and their use as anti-depressants
7465734	Methods and compositions for overcoming resistance to biologic and chemotherapy
7465741	C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
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BioPortfolio Ltd. offers e-mail and postal lists for Arachnoiditis scientists - we have details of around 165 individuals working on Arachnoiditis .