Ascariasis

Ascariasis is a human disease caused by the parasitic roundworm Ascaris lumbricoides. Perhaps as many as one quarter of the world's people are infected[http://www.pnas.org/cgi/content/full/99/8/5533], and ascariasis is particularly prevalent in tropical regions and in areas of poor hygiene. Other species of the genus Ascaris are parasitic and can cause disease in domestic animals.Infection occurs through ingestion of food contaminated with fecal matter containing Ascaris eggs. The larvae hatch, burrow through the intestine, reach the lungs, and finally migrate up the respiratory tract. From there they are then reswallowed and mature in the intestine, growing up to 30 cm in length and anchoring themselves to the intestinal wall.Infections are usually asymptomatic, especially if the number of worms is small. They may however be accompanied by inflammation, fever, and diarrhea, and serious problems may develop if the worms migrate to other parts of the body. (From the Wikpedia article Ascariasis.)

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Recent Publications on Ascariasis:
Soil-transmitted helminths in relation to hemoglobin status among school children of the Kashmir Valley. Soil-transmitted helminths (STHs) remain a major threat to the health of...	22nd August, 2008	PG Department of Zoology, University of Kashmir, Srinagar, India.	J Parasitol. 2008 Jun;94(3):591-3. DOI Direct Link
Eosinophilic cholecystitis caused by Ascaris lumbricoides. Eosinophilic cholecystitis is caused by the accumulation of eosinophils in...	21st August, 2008		World J Gastroenterol. 2008 May 7;14(17):2783.
A randomized, double-blind, multicenter clinical trial on the efficacy of ivermectin against intestinal nematode infections in China. To assess the efficacy of ivermectin against intestinal nematode...	13th August, 2008	Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, WHO	Acta Trop. 2008 Jun;106(3):190-4. Epub 2008 Mar 27. DOI Direct Link
[Prediction of the time of development and survival of ascarid eggs in the soil in the Kursk Region] The paper shows that the currently available methods used to predict the...	23rd July, 2008		Med Parazitol (Mosk). 2008 Apr-Jun;(2):21-5.
Ascaris lumbricoides-induced interleukin-10 is not associated with atopy in schoolchildren in a rural area of the tropics. BACKGROUND: In areas where intestinal helminth infections are endemic,...	22nd July, 2008	Laboratorio de Investigaciones, Hospital Pedro Vicente Maldonado,	J Infect Dis. 2008 May 1;197(9):1333-40. DOI Direct Link
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Ascariasis Clinical Trials:
Efficacy Albendazole and Levamisole Against STH on Unguja	Ascariasis;   Trichuriasis

Ascariasis Patents:
US Patent No.	Title
7208470	Method of treating reproductive system cancer by administering follistatin-3
7247725	Gamma-aminoamide modulators of chemokine receptor activity
7265201	Human chemotactic cytokine
7273613	Diagnostics and therapy of Epstein-Barr virus in autoimmune disorders
7273852	Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases
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