Ascariasis

Ascariasis is a human disease caused by the parasitic roundworm Ascaris lumbricoides. Perhaps as many as one quarter of the world's people are infected[http://www.pnas.org/cgi/content/full/99/8/5533], and ascariasis is particularly prevalent in tropical regions and in areas of poor hygiene. Other species of the genus Ascaris are parasitic and can cause disease in domestic animals.Infection occurs through ingestion of food contaminated with fecal matter containing Ascaris eggs. The larvae hatch, burrow through the intestine, reach the lungs, and finally migrate up the respiratory tract. From there they are then reswallowed and mature in the intestine, growing up to 30 cm in length and anchoring themselves to the intestinal wall.Infections are usually asymptomatic, especially if the number of worms is small. They may however be accompanied by inflammation, fever, and diarrhea, and serious problems may develop if the worms migrate to other parts of the body. (From the Wikpedia article Ascariasis.)

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Recent Publications on Ascariasis:
Intestinal and biliary infection with Ascaris lumbricoides in gastrointestinal endoscopy. Two unusual autopsy cases of fatal Ascaris infection have been presented....	29th October, 2009	Service of Digestive Diseases, Hospital Rio Hortega, Valladolid, Spain.	Rev Esp Enferm Dig. 2009 Jun;101(6):427-8, 429.
Endoscopic ultrasound for ascariasis in common bile duct. Two unusual autopsy cases of fatal Ascaris infection have been presented....	24th October, 2009	Jaswant Rai Speciality Hospital, Saket, Meerut-250001, Uttar Pradesh,	Endoscopy. 2009;41 Suppl 2:E209-10. Epub 2009 Jul 27. DOI Direct Link
[Children's abdominal pain--from symptoms to diagnosis] Abdominal pain is an ambiguous symptom and for this reason it is a common...	7th October, 2009	Institute of Teaching Nursing, Medical University of Lodzi.	Pol Merkur Lekarski. 2009 May;26(155):358-61.
Surgical Diagnosis and Management of Intestinal Obstruction Due to Ascaris lumbricoides. Abstract Background: Ascariasis continues to be one of the most...	30th September, 2009	1 San Lorenzo Mother and Child Center, Universidad Nacional de Asuncion ,	Surg Infect (Larchmt). 2009 Sep 28. DOI Direct Link
Erythema nodosum caused by ascariasis and Chlamydophila pneumoniae pulmonary infection--a case report. Erythema nodosum belongs to a group of relatively common hypodermal...	29th September, 2009	Department of Dermatology, Silesian Medical University in Katowice,	FEMS Immunol Med Microbiol. 2009 Dec;57(3):236-8. Epub 2009 Aug 21. DOI Direct Link
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Ascariasis Patents:
US Patent No.	Title
7396840	Chemokine receptor binding heterocyclic compounds
7479496	Substituted spiro azabicyclics as modulators of chemokine receptor activity
7482013	Albumin fusion proteins
7482335	Cyclic derivatives as modulators of chemokine receptor activity
7491390	Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
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