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Astrocytoma

Astrocytomas are primary intracranial tumors derived from astrocytes cells of the brain. They may arise in the cerebral hemispheres, in the posterior fossa, in the optic nerve, and rarely, the spinal cord. The WHO has given a four point scale depending on the histologic grade of the tumor . This article focuses on the well-differentiated astrocytoma. For grade 1 and 4 astrocytomas, see respective article headings: (From the Wikpedia article Astrocytoma.)

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Recent Publications on Astrocytoma:

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Extracellular Osmolarity Modulates G protein-Coupled Receptor Dependent ATP Release from 1321N1 Astrocytoma Cells.
We previously reported that ATP release from 1321N1 human astrocytoma...
13th November, 2009
1Case Western Reserve University. Am J Physiol Cell Physiol. 2009 Nov 11.
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Characterization of R132H Mutation-specific IDH1 Antibody Binding in Brain Tumors.
Heterozygous point mutations of isocitrate dehydrogenase (IDH)1 codon 132...
12th November, 2009
Department of Neuropathology, Institute of Pathology, Brain Pathol. 2009 Oct 27.
DOI Direct Link
Multiple extracranial metastases from secondary glioblastoma multiforme: a case report and review of the literature.
Extracranial metastasis of glioblastoma multiforme (GBM) is very rare, in...
10th November, 2009
Department of Radiation Oncology, Qilu Hospital, Shandong University, J Neurooncol. 2009 Nov 7.
DOI Direct Link
Primary spinal cord glioma: a Surveillance, Epidemiology, and End Results database study.
To characterize the overall survival (OS) and cause specific survival...
10th November, 2009
Department of Radiation Oncology, University of Rochester Medical Center, J Neurooncol. 2009 Nov 7.
DOI Direct Link
Treatment of malignant gliomas with TGF-beta2 antisense oligonucleotides.
Antisense oligodeoxynucleotides (AS-ODNs) have been widely used to...
10th November, 2009
Department of Neurology, University of Regensburg, Medical School, Expert Rev Anticancer Ther. 2009 Nov;9(11):1663-74.
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Press Releases About Astrocytoma:

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Clinical Proof of Concept for TGF-beta 2-Inhibitor AP 12009 in Phase Iib EMEA provides Guidance on Phase III Design and Approval Requirements 2nd June, 2008 Antisense Pharma GmbH
CHICAGO and REGENSBURG, Germany, June 2 /PRNewswire/ -- "A two-year survival rate of more than 80 percent in recurrent or refractory anaplastic astrocytoma suggests a breakthrough in this

BioNews Results for Astrocytoma:

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Research and Markets: Competitor Analysis: TGF-R Agonists and Antagonists - A Competitor Evaluation in the Field of Transforming Growth Factor Recepto
Yahoo! Canada:  Nov 11 2009 3:11PM Matching: astrocytoma
Findings May Spur Development of Drugs to Treat Brain Tumors in Infants
Biotech Daily:  Nov 9 2009 4:22PM Matching: astrocytoma
Caspase-dependent generation of reactive oxygen species in human astrocytoma cells contributes to resistance to TRAIL-mediated apoptosis
Cell Death and Differentiation:  Oct 30 2009 3:20PM Matching: astrocytoma
Mutation linked to pediatric brain tumor may pave way for targeted treatment
Washington University in St. Louis:  Oct 29 2009 10:24PM Matching: astrocytoma
Analysis of the mismatched manifestation between rCBF and rCBV maps in cerebral astrocytomas
Clinical Imaging:  Oct 28 2009 7:25AM Matching: astrocytoma
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Astrocytoma Clinical Trials:

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Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas

Astrocytoma Patents:

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US Patent No.Title
7595154 Method of detecting a neoplasia associated with an activating platelet derived growth factor receptor alpha (PDGFRA) mutation
7599745 Treating a tumor or the like with an electric field
7601355 Compositions and methods for altering immune function
7601359 Compositions and methods for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress proteins
7601496 Cleavage of nucleic acids

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Companies working in the area of Astrocytoma from Bioportfolio's Biocorporate database :

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Company Name

Protox Therapeutics Inc.

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases....
www.protoxtherapeutics.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Astrocytoma scientists - we have details of around 1338 individuals working on Astrocytoma .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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