Friday November 27 2009 | Biotechnology feed | All feeds
|
|
|
AtherosclerosisAtherosclerosis is a disease affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part due to the deposition of lipoproteins . It is commonly referred to as a "hardening" or "furring" of the arteries. It is caused by the formation of multiple plaques within the arteries.The atheromatous plaque is divided into three distinct components:# The atheroma , which is the nodular accumulation of a soft, flaky, yellowish material at the center of large plaques, composed of macrophages nearest the lumen of the artery# Underlying areas of cholesterol crystals# Calcification at the outer base of older/more advanced lesions.The following terms are similar, yet distinct, in both spelling and meaning, and can be easily confused: arteriosclerosis, arteriolosclerosis, and atherosclerosis. Arteriosclerosis is a general term describing any hardening of medium or large arteries , arteriolosclerosis is any hardening of arterioles , atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. Therefore, atherosclerosis is a form of arteriosclerosis. Atherosclerosis causes two main problems. First, the atheromatous plaques, though long compensated for by artery enlargement, see IMT, eventually lead to plaque ruptures and stenosis of the artery and, therefore, an insufficient blood supply to the organ it feeds. If the compensating artery enlargement process is excessive, then a net aneurysm results.These complications are chronic, slowly progressing and cumulative. Most commonly, soft plaque suddenly ruptures , causing the formation of a thrombus that will rapidly slow or stop blood flow, that is, within 5 minutes, leading to death of the tissues fed by the artery. This catastrophic event is called an infarction. One of the most common recognized scenarios is called coronary thrombosis of a coronary artery, causing myocardial infarction . Another common scenario in very advanced disease is claudication from insufficient blood supply to the legs, typically due to a combination of both stenosis and aneurysmal segments narrowed with clots. Since atherosclerosis is a body-wide process, similar events occur also in the arteries to the brain, intestines, kidneys, legs, etc. (From the Wikpedia article Atherosclerosis.) Download PDF containing detailed information. Image ResultsLoading...
BioPortfolio Ltd. offers e-mail and postal lists for Atherosclerosis scientists - we have details of around 6229 individuals working on Atherosclerosis . This page has been viewed 458 times Recent Search Terms used to find this page: rome atherosclerosis research | medical school of vienna discovers hardened arteries | Modes of Defining Atherosclerosis in Mouse Models Relative Merits and Evolving Standards | atherosclerosis in depth | atherosclerosis company | atherosclerosis companies | atherosclerosis conference 2009 | atherosclerosis causes pdf | atherosclerosis companies | . Browse BioPortfolio's InDepth service - alphabetically: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z or by Most Publications, recently searched for, or most viewed. Search for Atherosclerosis across BioPortfolio, or for Atherosclerosis Research Reports Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Nothing in this website should be used in
place of personal medical advice from your own qualified medical
practitioner. |
All rights reserved. All other trademarks recognized. |
|
