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Atrophy

Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, disuse or lack of exercise or disease intrinsic to the tissue itself. Hormonal and nerve inputs that maintain an organ or body part are referred to as trophic.Atrophy is a general physiological process of reabsorption and breakdown of tissues, involving apoptosis on a cellular level. When it occurs as a result of disease or loss of trophic support due to other disease, it is termed pathological atrophy, although it can be a part of normal body development and homeostasis as well. (From the Wikpedia article Atrophy.)

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Recent Publications on Atrophy:

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Executive control function, brain activation and white matter hyperintensities in older adults.
Context: Older adults responding to executive control function (ECF) tasks...
20th November, 2009
Department of Bioengineering, School of Engineering, University of Neuroimage. 2009 Nov 13.
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Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissue.
ABSTRACT: BACKGROUND: Oxaliplatin and related chemotherapeutic drugs cause...
20th November, 2009
Mol Pain. 2009 Nov 18;5(1):66.
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Genetic Study of Demyelinating form of Autosomal-Recessive Charcot-Marie-Tooth Diseases in a Turkish Family.
Charcot-Marie-Tooth (CMT) disease is a clinically and genetically...
20th November, 2009
Department of Medical Biology, Suleyman Demirel University, Faculty of Int J Neurosci. 2009;119(8):1179-1189.
SOD1 G93D mutation presenting as paucisymptomatic amyotrophic lateral sclerosis.
We describe a patient with a familial form of amyotrophic lateral...
20th November, 2009
Istituto di Neurologia. Amyotroph Lateral Scler. 2009;10(5-6):479-482.
The importance of the SMN genes in the genetics of sporadic ALS.
The human genome contains two SMN (survival motor neuron) genes: SMN1, the...
20th November, 2009
ALS Centre. Amyotroph Lateral Scler. 2009;10(5-6):436-440.

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Press Releases About Atrophy:

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Repligen Reports Second Quarter Fiscal Year 2010 Financial Results 5th November, 2009 Repligen Corporation
WALTHAM, Mass., Nov. 5 /PRNewswire-FirstCall/ -- Repligen Corporation (Nasdaq: RGEN) today reported results for the second quarter of fiscal year 2010, ended September 30, 2009. Total revenue for the
Families of Spinal Muscular Atrophy Licenses Potential Treatment for SMA to Repligen Corporation 22nd October, 2009 Families of Spinal Muscular Atrophy
ELK GROVE VILLAGE, Ill., Oct. 22 /PRNewswire-USNewswire/ -- Families of Spinal Muscular Atrophy (FSMA) announced today that it has entered into a groundbreaking exclusive license agreement with
Repligen Licenses Potential Treatment for Spinal Muscular Atrophy 22nd October, 2009 Repligen Corporation
WALTHAM, Mass., Oct. 22 /PRNewswire-FirstCall/ -- Repligen Corporation (Nasdaq: RGEN) announced today that it has entered into an exclusive license agreement with Families of Spinal Muscular Atrophy
Reportlinker Adds Therapeutics for Memory and Cognition Disorders Report 3rd September, 2009 Reportlinker
-- Analyzes the market outlook, trends, and challenges. Chapter-1: SUMMARY SUMMARY TABLE WORLDWIDE POTENTIAL MARKET FOR MEMORY/COGNITION THERAPEUTICS, BY DISEASE AREA, THROUGH 2014 ($
Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs 19th June, 2009 Families of Spinal Muscular Atrophy
LIBERTYVILLE, Ill., June 18 /PRNewswire-USNewswire/ -- Families of Spinal Muscular Atrophy has just released details of the latest developments for the Families of SMA funded therapeutic pipeline.

BioNews Results for Atrophy:

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White Matter Lesions and Lacunar Infarcts Are Independently and Differently Associated with Brain Atrophy: The SMART-MR Study
MDLinx:  Nov 18 2009 12:28PM Matching: atrophy
Cancer: Findings from University of Liverpool advance knowledge in cancer
NewsRX:  Nov 15 2009 6:05AM Matching: atrophy
Unique Therapeutic Candidate To Treat Spinal Muscular Atrophy Identified
MedIndia:  Nov 9 2009 1:27PM Matching: atrophy
Medical News: Drug Candidate For Treating Spinal Muscular Atrophy Identified By Researchers
BioFind:  Nov 5 2009 3:57PM Matching: atrophy
Drug Candidate For Treating Spinal Muscular Atrophy Identified By Researchers
Medical News Today:  Nov 5 2009 12:44PM Matching: atrophy
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Atrophy Patents:

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US Patent No.Title
7611847 Method for identifying an intestinal phenotype
7613343 Nosologic system of diagnosis
7613495 MRI detection and staging of Parkinson's disease and detection of progressive supranuclear palsy
7613515 High frequency vagal blockage therapy
7613516 Pelvic disorder treatment device

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Companies working in the area of Atrophy from Bioportfolio's Biocorporate database :

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Company Name

Neurotech USA, Inc

Neurotech is a biotechnology company dedicated to the development of sight-saving therapeutics for chronic retinal diseases. Retinal diseases represent significant unmet medical needs for which new...
www.neurotechusa.com/        View full profile
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QuatRx Pharmaceuticals

QuatRx Pharmaceuticals Company is a pharmaceutical company focused on discovering, licensing, developing and commercializing compounds in the endocrine, metabolic and cardiovascular therapeutic areas....
www.quatrx.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Atrophy scientists - we have details of around 6283 individuals working on Atrophy .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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