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Batroxobin

Batroxobin is a serine protease derived from the venom of Bothrops atrox. (From the Wikpedia article Batroxobin.)

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Recent Publications on Batroxobin:

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Influence of direct thrombin inhibitor argatroban on coagulation assays in healthy individuals, patients under oral anticoagulation therapy and patients with liver dysfunction.
We assumed that argatroban, a direct thrombin inhibitor, has a strong...
18th July, 2008
Institut fur Klinische Chemie und Laboratoriumsdiagnostik, Blood Coagul Fibrinolysis. 2008 Jun;19(4):288-93.
DOI Direct Link
Effect of hemocoagulase for prevention of pulmonary hemorrhage in critical newborns on mechanical ventilation: a randomized controlled trial.
OBJECTIVE: To investigate the role of hemocoagulase to prevent pulmonary...
11th July, 2008
Department of Pediatrics, Research Institute of Surgery and Daping Indian Pediatr. 2008 Mar;45(3):199-202.
Immune complex-mediated glomerulonephritis is ameliorated by thrombin-activatable fibrinolysis inhibitor deficiency.
The activity of plasmin plays a critical role in the development of...
10th July, 2008
Department of Immunology, Mie University Graduate School of Medicine, Thromb Haemost. 2008 Jul;100(1):90-100.
Cleavage of factor XIII by human neutrophil elastase results in a novel active truncated form of factor XIII A subunit.
The first step in the activation of plasma factor XIII (FXIII) is the...
28th June, 2008
University of Debrecen, Medical and Health Science Center, Clinical Thromb Haemost. 2008 Apr;99(4):668-74.
GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans.
Mass spectrometry is the main analytical technique currently used to...
24th June, 2008
Division of Molecular Biosciences, Imperial College London, London SW72AZ, J Proteome Res. 2008 Apr;7(4):1650-9. Epub 2008 Mar 1.
DOI Direct Link

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Batroxobin Patents:

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US Patent No.Title
6395889 Nucleic acid molecules encoding human protease homologs
6627215 Devices for improved wound management
6630139 Fibrinogenolytic proteases with thrombolytic and antihypertensive activities: medical application and novel process of expression and production
6682520 Tissue volume reduction
6699484 Fibrin sealants or adhesives comprising a hyaluronic acid derivative material

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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