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Blepharospasm

A blepharospasm is any abnormal tic or twitch of the eyelid . However, it is normally distinguished from less serious disorders and refers to Benign Essential Blepharospasm, a focal dystonia of the muscles around the eyes. The cause is often undetermined, but fatigue or an irritant are possible contributing factors. Symptoms usually last for a few days then disappear without treatment, but in some cases the twitching is chronic and persistent. Occasionally, the symptoms are severe enough to result in effective blindness. (From the Wikpedia article Blepharospasm.)

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Recent Publications on Blepharospasm:

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A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation.
To evaluate pallidal DBS in a non-DYT1 form of hereditary dystonia. We...
6th November, 2009
Department of Neurosurgery, University Hospital of Northern Sweden, Umea, Mov Disord. 2009 Nov 4.
DOI Direct Link
Use of Botulinum A Toxin (BOTOX) in Different Types of Facial Dystonia.
This study was carried out in the Eye Departments of Combined Military...
6th November, 2009
Department of Ophthalmology, Combined Military Hospital, Kharian Cantt. J Coll Physicians Surg Pak. 2009 Nov;19(11):742-3.
DOI Direct Link
[5/6 Care and treatment of the aged]
Botulism is a severe neuroparalytic disease caused by toxins produced by...
5th November, 2009
Soins Gerontol. 2009 Sep-Oct;(79):45-6.
Feline entropion: a case series of 50 affected animals (2003-2008).
AIM: To evaluate the signalment, clinical signs, and etiopathogenesis of...
29th October, 2009
Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 Vet Ophthalmol. 2009 Jul-Aug;12(4):221-6.
DOI Direct Link
Botulinum toxin in facial rejuvenation: an update.
Since its initial approval by the US Food and Drug Administration (FDA) 20...
24th October, 2009
Department of Ophthalmology and Visual Sciences, University of British Dermatol Clin. 2009 Oct;27(4):417-25, v.
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Press Releases About Blepharospasm:

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Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients 28th April, 2009 Merz Pharmaceuticals
SEATTLE, April 28 /PRNewswire/ -- Results from two prospective, double-blind placebo controlled multi-center studies in patients with cervical dystonia and blepharospasm, and pooled European efficacy

BioNews Results for Blepharospasm:

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Xeomin receives approval for post-stroke spasticity of upper limb in European countries
News-Medical.Net:  Nov 19 2009 6:54AM Matching: blepharospasm
Merz Pharmaceuticals Announces Approval of Post-stroke Upper Limb Spasticity Indication for Xeomin in the EU
Pharma Live:  Nov 19 2009 12:45AM Matching: blepharospasm
Extension Application for Xeomin for the New Indication Spasticity was Approved in Various European Countries
Pharma Live:  Nov 18 2009 7:41PM Matching: blepharospasm
Merz Pharmaceuticals Announces Approval of Post-stroke Upper Limb Spasticity Indication for Xeomin(R) in the EU
Red Orbit:  Nov 18 2009 7:27PM Matching: blepharospasm
Merz Pharmaceuticals Announces Approval of Post-stroke Upper Limb Spasticity Indication for Xeomin(R) in the E
NewsBlaze:  Nov 18 2009 1:35PM Matching: blepharospasm
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Blepharospasm Patents:

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US Patent No.Title
7404969 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
7462699 BoNT/A peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy
7465458 Methods for treating eye disorders
7468188 Multi-step therapy for injured muscles
7468189 Neuropathic pain treatment method

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BioPortfolio Ltd. offers e-mail and postal lists for Blepharospasm scientists - we have details of around 130 individuals working on Blepharospasm .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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