Bronchiectasis

Bronchiectasis is a disease that causes localized, irreversible dilatation of part of the bronchial tree. Involved bronchi are dilated, inflamed, and easily collapsible, resulting in airflow obstruction and impaired clearance of secretions. Bronchiectasis is associated with a wide range of disorders, but it usually results from necrotizing bacterial infections, such as infections caused by the Staphylococcus or Klebsiella species or Bordetella pertussis.Rene Theophile Hyacinthe Laënnec, the man who invented the stethoscope, used his creation to first discover bronchiectasis in 1819.. The disease was researched in greater detail by Sir William Osler in the late 1800s; in fact, it is suspected that Osler actually died of complications from undiagnosed bronchiectasis. (From the Wikpedia article Bronchiectasis.)

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Recent Publications on Bronchiectasis:
[Primary ciliary dyskinesia (Pcd) in Austria.] INTRODUCTION: Primary ciliary dyskinesia (PCD) is a rare hereditary...	19th November, 2009	Medizinische Universitat Wien, Universitatsklinik fur Kinder- und	Wien Klin Wochenschr. 2009 Oct;121(19-20):616-622. DOI Direct Link
Primary IgA and IgG subclass deficiency in a 17-year-old Pakistani girl: a case report. Primary immunodeficiency disorders pose a diagnostic dilemma for...	18th November, 2009		Cases J. 2009 Aug 10;2:6785. DOI Direct Link
Echocardiographic abnormalities and their correlation with bronchiectasis score in primary antibody deficiencies. BACKGROUND: Primary antibody deficiencies are characterized by defective...	18th November, 2009	aGrowth and Development Research Center, Iran bDepartment of Pediatrics,	J Cardiovasc Med (Hagerstown). 2009 Nov 13. DOI Direct Link
Effect of mannitol and repetitive coughing on the sputum properties in bronchiectasis. Mucociliary clearance increases with increasing doses of mannitol and...	17th November, 2009	Department of Respiratory & Sleep Medicine, Royal Prince Alfred Hospital,	Respir Med. 2009 Nov 13. DOI Direct Link
Detection of pulmonary complications in common variable immunodeficiency. Touw CML, van de Ven AA, de Jong PA, Terheggen-Lagro S, Beek E, Sanders...	17th November, 2009	Department of Pediatric Immunology and Infectious Diseases, University	Pediatr Allergy Immunol. 2009 Nov 13. DOI Direct Link
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Press Releases About Bronchiectasis:
Transave Completes Enrollment in Arikace(TM) Phase II Bronchiectasis Study	21st April, 2009	Transave, Inc.	Presently No Approved Treatments MONMOUTH JUNCTION, N.J., April 21 /PRNewswire/ -- Transave, Inc., today reported completion of patient enrollment in a Phase II study evaluating the safety and
Transave, Inc. Secures $12.5 Million in New Financing	2nd October, 2008	Transave, Inc.	STRENGTH OF PHASE II DATA FOR LEAD DRUG CANDIDATE ARIKACE(TM) DRIVES CONTINUED CLINICAL EXPANSION MONMOUTH JUNCTION, N.J., Oct. 2 /PRNewswire/ -- Transave, Inc., a biopharmaceutical company focused

BioNews Results for Bronchiectasis:
Aradigm Doses First Patient in Long-Term Phase 2 Study of a Novel Inhaled Ciprofloxacin Formulation for the Management of Respiratory Infections in Br	Yahoo! Canada:  Nov 16 2009 2:27PM Matching: bronchiectasis
New Lung Health Research Presented At CHEST 2009	Medical News Today:  Nov 5 2009 12:46PM Matching: bronchiectasis
UIC Pulmonologist Named President of Thoracic Society	Newswise:  Oct 27 2009 4:46PM Matching: bronchiectasis

Bronchiectasis Patents:
US Patent No.	Title
7534438	Product and process for liquefaction of mucus or sputum
7553828	9-aminomethyl substituted minocycline compounds
7553944	Human virus causing respiratory tract infection and uses thereof
7553966	Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
7557185	Moraxella catarrhalis proteins
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