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Butyrylcholinesterase

Butyrylcholinesterase, also known as BCHE, is a human gene. Butyrylcholinesterase is also called serum cholinesterase. It is very similar to the neuronal acetylcholinesterase. Butyrylcholine is a synthetic compound and does not occur in the body naturally. It is used as a tool to distinguish between acetyl- and butyrylcholinesterase.}} (From the Wikpedia article Butyrylcholinesterase.)

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Recent Publications on Butyrylcholinesterase:

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BuChE-K and APOE epsilon4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline.
Apolipoprotein E (APOE) epsilon4 and butyrylcholinesterase-K (BuChE-K) are...
14th November, 2008
Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA. Mov Disord. 2008 Nov 12.
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The effect of HI-6 on cholinesterases and on the cholinergic system of the rat bladder.
OBJECTIVES: The current standard treatment of organophosphate poisoning...
7th November, 2008
Department of Toxicology, Faculty of Military Health Sciences, University Neuro Endocrinol Lett. 2008 Oct 11;29(5):759-762.
Influence of differential expression of acetylcholinesterase in brain and muscle on respiration.
A mouse strain with a deleted acetylcholinesterase (AChE) gene (AChE...
4th November, 2008
Neurobiologie Genetique et Integrative, Institut de Neurobiologie Alfred Respir Physiol Neurobiol. 2008 Oct 11.
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Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.
Human butyrylcholinesterase (hBChE) hydrolyzes or scavenges a wide range...
4th November, 2008
J Am Chem Soc. 2008 Nov 1.
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Multienzyme electrochemical array sensor for determination of phenols and pesticides.
The screen-printed four-electrode system was used as the amperometric...
31st October, 2008
Department of Biochemistry, Masaryk University, Kotlarska 2, 61137 Brno, Talanta. 2005 Jan 30;65(2):349-57.
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BioNews Results for Butyrylcholinesterase:

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PharmAthene Presents Data for Protexia and Valortim at 2008 BARDA Industry Conference / PHEMCE Stakeholders Wo
Pharma Live:  Sep 24 2008 2:19PM Matching: butyrylcholinesterase

Butyrylcholinesterase Clinical Trials:

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A Study of Plasma-Derived Human Butyrylcholinesterase Administered Intramuscularly
Healthy Interventions: Drug: Human butyrylcholinesterase (HuBChE) derived from human plasma;   Drug: Placebo: Normal saline

Butyrylcholinesterase Patents:

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US Patent No.Title
6642037 Preparation of enzymatically active sponges or foams for detoxification of hazardous compounds
6770799 Expression of recombinant human acetylcholinesterase in transgenic plants
6835569 Amino polyol oxidase amine polynucleotides and related polypeptides and methods of use
6849376 Polymers and photoresist compositions comprising same
6852525 Mammalian cell culture chamber

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.

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