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Cachexia

Cachexia is loss of weight, muscle atrophy, fatigue, weakness and significant loss of appetite in someone who is not actively trying to lose weight. It can be a sign of various underlying disorders; when a patient presents with cachexia, a doctor will generally consider the possibility of cancer, certain infectious diseases and some autoimmune disorders, or addiction to drugs such as amphetamines or cocaine.Cachexia physically weakens patients to a state of immobility stemming from loss of appetite, asthenia, and anemia, and response to standard treatment is usually poor. (From the Wikpedia article Cachexia.)

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Recent Publications on Cachexia:

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An Innovative Treatment Approach for Cancer-Related Anorexia/Cachexia and Oxidative Stress: Background and Design of an Ongoing, Phase III, Randomized Clinical Trial.
BACKGROUND: -The Stent or Surgery Trial is a randomized, controlled trial...
18th July, 2008
Department of Medical Oncology, University of Cagliari, Italy. Support Cancer Ther. 2007 May 1;4(3):163-7.
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Evaluation of nutritional status and dietary intake in patients with advanced cancer on palliative care.
AIM: Cancer cachexia and malnutrition are very common in patients...
11th July, 2008
Metabolic-Nutritional Unit, Salvatore Maugeri Foundation, IRCCS Minerva Gastroenterol Dietol. 2008 Sep;54(3):243-50.
Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia.
Purpose. Cancer-related cachexia is an obscure syndrome leading to muscle...
9th July, 2008
Department of Radiology, German Cancer Research Center (dkfz), Heidelberg, Acta Oncol. 2008 May 19;:1-9.
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Electrical stimulation and muscle strengthening.
OBJECTIVES: To identify the effects of application methods and indications...
8th July, 2008
EA 4136 handicap et systeme nerveux, service de medecine physique et Ann Readapt Med Phys. 2008 Jun 18;.
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mPGES-1 knock-out mice are resistant to cancer-induced anorexia despite the absence of central mPGES-1 up-regulation in wild-type anorexic mice.
Anorexia-cachexia syndrome is a very common symptom observed in...
8th July, 2008
Centre de Recherche en Neurobiologie-Neurophysiologie de Marseille J Neuroimmunol. 2008 Jul 3;.
DOI Direct Link

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BioNews Results for Cachexia:

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Effects of Lung Volume Reduction Surgery for Emphysema on Glycolipidic Hormones
CHEST:  Jul 15 2008 4:38PM Matching: cachexia
Advanced Viral Receives Notice of Allowance for Patents
Genetic Engineering News:  Jul 14 2008 4:30PM Matching: cachexia
Advanced Viral Receives Notice of Allowance for Patents
NewsBlaze:  Jul 14 2008 4:09PM Matching: cachexia
Inovio Biomedical and VGX Pharmaceuticals Sign
Citybizlist:  Jul 8 2008 5:21PM Matching: cachexia
Stem Cell Transplant Effective For Mngie
Neurology Today:  Jul 8 2008 2:22PM Matching: cachexia
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Cachexia Clinical Trials:

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Multimodal Treatment Strategy for Cancer Cachexia
Advanced Cancer;   Cachexia

Cachexia Patents:

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US Patent No.Title
7381738 Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity
7388009 Heteroaryl-substituted pyrrolo-triazine compounds useful as kinase inhibitors
7388027 Bicyclic compounds as modulators of androgen receptor function and method
7390519 Probiotic Lactobacillus salivarius strains
7390619 Optimization of immunomodulatory properties of genetic vaccines

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Companies working in the area of Cachexia from Bioportfolio's Biocorporate database :

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GTX

GTx, Inc., headquartered in Memphis, Tennessee, is a biopharmaceutical company dedicated to the discovery, development and commercialization of novel hormonal therapeutics for cancer and serious...
www.gtxinc.com/        View full profile
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Palatin Technologies

Palatin Technologies (AMEX:PTN) is a biopharmaceutical company primarily focused on discovering and developing targeted, receptor-specific small molecule and peptide therapeutics, including...
www.palatin.com/        View full profile
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Santhera Pharmaceuticals Holding Ltd

Santhera Pharmaceuticals is a Swiss biopharmaceutical company focusing on the discovery, development and marketing of small molecule pharmaceutical products for the treatment of neuromuscular diseases...
www.santhera.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Cachexia scientists - we have details of around 460 individuals working on Cachexia .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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