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Calciphylaxis

Calciphylaxis is a syndrome of vascular calcification and skin necrosis. It is seen almost exclusively in patients with end stage renal disease. It results in chronic non-healing wounds and requires parathyroidectomy and hyperbaric therapy. Calciphylaxis is a rare but serious disease. Calciphylaxis is one type of extraskeletal calcification. Similar extraskeletal calcifications are observed in some patients with hypercalcaemic states, including patients with milk alkali syndrome, sarcoidosis, primary hyperparathyroidism, and hypervitaminosis D. (From the Wikpedia article Calciphylaxis.)

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Recent Publications on Calciphylaxis:

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[Calcific uremic arteriolopathy (calciphylaxis)]
We present the case of a end stage renal failure patient treated with...
17th July, 2008
Centre de geriatrie du Bas-Valais, Clinique St-Ame, Route des Cases, 1890 Rev Med Suisse. 2008 May 7;4(156):1167-71.
Calciphylaxis in a patient with normal renal function: response to treatment with sodium thiosulfate.
Calciphylaxis is a rare, life-threatening cause of skin necrosis. The...
17th July, 2008
Department of Dermatology, Mater Misericordiae University Hospital, Clin Exp Dermatol. 2008 Jul 4;.
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[Calciphylaxis treated by cinacalcet: A medical alternative to parathyroidectomy.]
Calciphylaxis is a rare necrotizing calcifying arteriolopathy, with a poor...
28th June, 2008
Service de dermatologie, CHU Dupuytren, 2, avenue Martin-Luther-King, Rev Med Interne. 2008 Jun 24;.
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Bone scan findings in metastatic calcification from calciphylaxis.
A 51-year-old woman on peritoneal dialysis for chronic renal failure...
27th June, 2008
Section of Nuclear Medicine, University of Manitoba, Winnipeg, Manitoba, Clin Nucl Med. 2008 Jul;33(7):502-4.
DOI Direct Link
[Cardiovascular disease in chronic kidney failure]
A 51-year-old woman on peritoneal dialysis for chronic renal failure...
17th June, 2008
Nyremedisinsk avdeling, Ulleval universitetssykehus, 0407 Oslo. Tidsskr Nor Laegeforen. 2008 May 29;128(11):1297.

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Calciphylaxis Patents:

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US Patent No.Title
7318925 Methods of use for antibodies against parathyroid hormone
5254538 Method of treating periodontal disease
5597815 Prevention of hyperphosphatemia in kidney disorder patients
5939406 18-substituted-19-nor-vitamin D compounds
6281249 18-substituted-19-nor-vitamin D compounds

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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