Calciphylaxis

Calciphylaxis is a syndrome of vascular calcification and skin necrosis. It is seen almost exclusively in patients with end stage renal disease. It results in chronic non-healing wounds and requires parathyroidectomy and hyperbaric therapy. Calciphylaxis is a rare but serious disease. Calciphylaxis is one type of extraskeletal calcification. Similar extraskeletal calcifications are observed in some patients with hypercalcaemic states, including patients with milk alkali syndrome, sarcoidosis, primary hyperparathyroidism, and hypervitaminosis D. (From the Wikpedia article Calciphylaxis.)

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Recent Publications on Calciphylaxis:
Penile calciphylaxis: 5-year experience and literature review. INTRODUCTION: Necrosis of the penis is a rare conditon that may occur as a...	21st November, 2009	Servicio de Urologia, Hospital Universitario Dr. Jose E. Gonzalez,	Actas Urol Esp. 2009 Oct;33(9):1019-1023.
Sodium thiosulfate in the treatment of calcific uremic arteriolopathy. Calcific uremic arteriolopathy (CUA; also known as calciphylaxis) is a...	6th November, 2009	Department of Nephrology and Clinical Immunology, RWTH Aachen University	Nat Rev Nephrol. 2009 Sep;5(9):539-43. DOI Direct Link
Use of sodium thiosulfate in the treatment of calciphylaxis. Calciphylaxis is an infrequent but severe entity found in chronic dialysis...	29th October, 2009	Department of Nephrology, Hospital Italiano de Buenos Aires, Argentina.	Saudi J Kidney Dis Transpl. 2009 Nov;20(6):1065-8.
African American female with renal failure presenting with skin lesions: a case report. Calciphylaxis is a lethal disorder seen in patients with end-stage renal...	16th October, 2009	Department of Family Medicine and Public Health Sciences, Wayne State	Cases J. 2009 Jul 29;2:8701. DOI Direct Link
Proximal calciphylaxis in a patient with liver and kidney transplantation. Calciphylaxis is a lethal disorder seen in patients with end-stage renal...	13th October, 2009		Nefrologia. 2009 Oct;29(5):489-490. doi: DOI Direct Link
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BioNews Results for Calciphylaxis:
Calciphylaxis in chronic renal failure: An approach to risk factors	MDLinx:  Oct 20 2009 11:52AM Matching: calciphylaxis

Calciphylaxis Patents:
US Patent No.	Title
7553482	Use of a phosphate adsorbent to combat vascular diseases
5254538	Method of treating periodontal disease
5597815	Prevention of hyperphosphatemia in kidney disorder patients
5939406	18-substituted-19-nor-vitamin D compounds
6281249	18-substituted-19-nor-vitamin D compounds
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