Recent Publications on Calpain: |  |
Reduction of myocardial infarction by postischemic administration of the calpain inhibitor A-705253 in comparison to the Na(+)/H(+) exchange inhibitor Cariporide((R)) in isolated perfused rabbit hearts.
Abstract The calpain inhibitor A-705253 and the Na(+)/H(+)-exchange...
Direct Link | 11th October, 2008
| 1Division of Cardiology, Department of Internal Medicine, University of
|
Glucose-Regulated Protein 78 Antagonizes Cisplatin and Adriamycin in Human Melanoma Cells.
Resistance of melanoma cells to chemotherapeutics remains a major obstacle...
Direct Link | 10th October, 2008
| Immunology and Oncology Unit, Room 443, Newcastle Misericordiae Hospital,
|
The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration.
Cell migration involves the dynamic formation and release of...
Direct Link | 9th October, 2008
|
|
A novel calpain inhibitor, ((1S)-1((((1S)-1-BENZYL-3-CYCLOPROPYLAMINO-2,3-DI-OXOPROPYL)AMINO)CARBONYL )-3-METHYLBUTYL) carbamic acid 5-methoxy-3-oxapentyl ester, protects neuronal cells from cerebral ischemia-induced damage in mice.
Cerebral ischemia induces Ca(2+) influx into neuronal cells, and activates...
Direct Link | 7th October, 2008
| Department of Biofunctional Evaluation, Molecular Pharmacology, Gifu
|
Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice.
ABSTRACT: BACKGROUND: Familial Alzheimer's disease-linked variants of...
Direct Link | 7th October, 2008
|
|
Differences in Ischemia-Reperfusion Induced Endothelial Changes in Hearts Perfused at Constant Flow and Constant Pressure.
Isolated hearts subjected to ischemia-reperfusion (I/R) exhibit depressed...
Direct Link | 4th October, 2008
| Physiology, University of Manitoba, Winnipeg, Canada.
|
Involvement of calpain in the process of Jurkat T cell chemotaxis.
Massive T cell infiltration into the central nervous system is a hallmark...
Direct Link | 3rd October, 2008
| Department of Molecular and Cellular Biology and Pathobiology, Medical
|
Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5.
Altered glutamatergic and dopaminergic signaling has been proposed as...
Direct Link | 3rd October, 2008
| Departament de Biologia Cellular, Immunologia i Neurociencies, Facultat de
|
Delayed recovery of intracellular acidosis during reperfusion prevents calpain activation and determines protection in postconditioned myocardium.
AIMS: Indirect data suggest that delayed recovery of intracellular pH...
Direct Link | 3rd October, 2008
| Laboratorio de Cardiologia Experimental, Servicio de Cardiologia, Hospital
|
Calpain inhibitory flavonoids isolated from Orostachys japonicus.
The n-butanol (n-BuOH) fraction of Orostachys japonicus A. Berger...
Direct Link | 1st October, 2008
| College of Pharmacy and Research Institute of Pharmaceutical Science,
|
Calpain mediates cardiac troponin degradation and contractile dysfunction in atrial fibrillation.
The self-perpetuation of atrial fibrillation (AF) is associated with...
Direct Link | 1st October, 2008
| Department of Radiation and Stress Cell Biology, University Institute for
|
Identification of Small Molecule Inhibitors of (beta)-Amyloid Cytotoxicity through a Cell-Based High-Throughput Screening Platform.
Calpain activation is hypothesized to be an early occurrence in the...
Direct Link | 25th September, 2008
|
|
Role of calpains in postmortem proteolysis in chicken muscle.
Tenderness is governed by postmortem biochemical processes, particularly...
Direct Link | 24th September, 2008
| Laboratoire de Genie Chimique et Biochimique, Unite Biochimie,
|
Role of the calpain-calpastatin system in the density-dependent growth arrest.
In dividing cells calpastatin diffuses from aggregates into cytosol,...
Direct Link | 24th September, 2008
| Department of Experimental Medicine (DIMES), Section of Biochemistry,
|
An increase in intracellular Ca(2+) is required for the activation of mitochondrial calpain to release AIF during cell death.
Apoptosis-inducing factor (AIF), a flavoprotein with NADH oxidase activity...
Direct Link | 23rd September, 2008
| 1Institute of Environmental Medicine, Division of Toxicology, Karolinska
|
