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Capnography

Capnography is the monitoring of the concentration or partial pressure of carbon dioxide in the respiratory gases. Its main development has been as a monitoring tool for use during anaesthesia and intensive care. It is usually presented as a graph of expiratory CO2 plotted against time, or, less commonly, but more usefully, expired volume. The plot may also show the inspired CO2, which is of interest when rebreathing systems are being used.The capnogram is a direct monitor of the inhaled and exhaled concentration or partial pressure of CO2, and an indirect monitor of the CO2 partial pressure in the arterial blood. In healthy individuals, the difference between arterial blood and expired gas CO2 partial pressures is very small, and is probably zero in children. In the presence of most forms of lung disease, and some forms of congenital heart disease the difference between arterial blood and expired gas increases and can exceed 1 kPa.During anaesthesia, there is interplay between two components: the patient and the anaesthesia administration device . The critical connection between the two components is either an endotracheal tube or a mask, and CO2 is typically monitored at this junction. Capnography directly reflects the elimination of CO2 by the lungs to the anaesthesia device. Indirectly, it reflects the production of CO2 by tissues and the circulatory transport of CO2 to the lungs.When expired CO2 is related to expired volume rather than time, the area beneath the curve represents the volume of CO2 in the breath, and thus over the course of a minute, this method can yield the CO2 minute elimination, an important measure of metabolism. Sudden changes in CO2 elimination during lung or heart surgery usually imply important changes in cardiorespiratory function. Capnographs usually work on the principle that CO2 absorbs infra-red radiation. A beam of infra-red light is passed across the gas sample to fall on to a sensor. The presence of CO2 in the gas leads to a reduction in the amount of light falling on the sensor, which changes the voltage in a circuit. The analysis is rapid and accurate, but the presence of nitrous oxide in the gas mix changes the infra-red absorption via the phenomenon of collision broadening. This must be corrected for. (From the Wikpedia article Capnography.)

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Recent Publications on Capnography:

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Anatomic dead space cannot be predicted by body weight.
BACKGROUND: Anatomic dead space (also called airway or tracheal dead...
3rd July, 2008
Respir Care. 2008 Jul;53(7):885-91.
Capnography and respiratory care in the 21st century.
BACKGROUND: Anatomic dead space (also called airway or tracheal dead...
3rd July, 2008
Respiratory Care Services, San Francisco General Hospital, NH:GA-2, 1001 Respir Care. 2008 Jul;53(7):860-1.
Accuracy and precision of three different methods to determine Pco2 (Paco2 vs. Petco2 vs. Ptcco2) during interhospital ground transport of critically ill and ventilated adults.
BACKGROUND: Interhospital transportation of critically ill and...
27th June, 2008
Clinic for Anesthesiology and Intensive Care Medicine, J Trauma. 2008 Jul;65(1):10-8.
DOI Direct Link
Impact of volume targeting on efficacy of bi-level non-invasive ventilation and sleep in obesity-hypoventilation.
BACKGROUND: Volume targeting by bi-level positive pressure ventilation...
27th June, 2008
Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Respir Med. 2008 Jun 23;.
DOI Direct Link
Nurse-administered propofol sedation compared with midazolam and meperidine for EUS: a prospective, randomized trial.
BACKGROUND: The utility of nurse-administered propofol sedation (NAPS)...
20th June, 2008
Current affiliations: Departments of Gastroenterology and Hepatology, Gastrointest Endosc. 2008 Jun 16;.
DOI Direct Link

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BioNews Results for Capnography:

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Oximetry With Capnography Defines Oxygen Therapy Needs
Medscape:  Jul 12 2008 4:14AM Matching: capnography
Combined Oximetry-Cutaneous Capnography in Patients Assessed for Long-term Oxygen Therapy
CHEST:  Jun 24 2008 4:27AM Matching: capnography

Capnography Clinical Trials:

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The Use of Capnography as a Guide for Oral Intubation
Intubation, Intratracheal

Capnography Patents:

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US Patent No.Title
6556865 Method for improving cardiac function following delivery of a defibrillation shock
6828910 Apparatus for monitoring gas concentrations
6836679 Method and apparatus for estimating physiological parameters using model-based adaptive filtering
6865407 Calibration technique for non-invasive medical devices
6878938 High frequency infrared radiation source

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BioPortfolio Ltd. offers e-mail and postal lists for Capnography scientists - we have details of around 102 individuals working on Capnography .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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