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Carboxy-Lyases

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Recent Publications on Carboxy-Lyases:

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Integrated metabolite and gene expression profiling revealing phytochrome A regulation of polyamine biosynthesis of Arabidopsis thaliana.
In this study, metabolite profiling was demonstrated as a useful tool to...
25th June, 2008
Department of Biotechnology, Graduate School of Engineering, Osaka J Exp Bot. 2008;59(6):1187-200. Epub 2008 Mar 28.
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Defining the importance of phosphatidylserine synthase-1 (PSS1): unexpected viability of PSS1-deficient mice.
Phosphatidylserine (PS) is a quantitatively minor, but physiologically...
18th June, 2008
University of Alberta, Edmonton, Alberta T6G 2S2, Canada. J Biol Chem. 2008 May 9;283(19):12888-97. Epub 2008 Mar 14.
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Saturation mutagenesis of putative catalytic residues of benzoylformate decarboxylase provides a challenge to the accepted mechanism.
Benzoylformate decarboxylase from Pseudomonas putida (PpBFDC) is a thiamin...
14th June, 2008
College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5733-8. Epub 2008 Apr 8.
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Modeling the resting state of oxalate oxidase and oxalate decarboxylase enzymes.
In view of the biological and commercial interest in models for Oxalate...
11th June, 2008
Willard H. Dow Laboratories, Department of Chemistry, University of Inorg Chem. 2008 May 5;47(9):3584-93. Epub 2008 Apr 10.
DOI Direct Link
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.
Previous studies have suggested that insulin resistance develops secondary...
31st May, 2008
Sarah W. Stedman Nutrition and Metabolism Center, Department of Medicine, Cell Metab. 2008 Jan;7(1):45-56.
DOI Direct Link

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BioNews Results for Carboxy-Lyases:

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Cysteine variants of erythropoietin
PharmCast:  Apr 1 2008 4:04AM Matching: carboxy

Carboxy-Lyases Clinical Trials:

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Effects of Recombinant Human Glutamic Acid Decarboxylase . . .
Type 1 Diabetes Mellitus
A Phase 2b Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa
Parkinson's Disease
Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis.
Colorectal Cancer;   Precancerous/Nonmalignant Condition
Difluoromethylornithine (DFMO) Chemoprevention of Skin Cancer in Organ Transplant Recipients
Post-Solid Organ Transplant;   Skin Neoplasms
Follow Up Safety Study of SCH 420814 in Subjects With Parkinson's Disease (P05175)
Parkinson Disease;   Neurodegenerative Diseases;   Central Nervous System Diseases;   Movement Disorders;   Brain Diseases

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Carboxy-Lyases Patents:

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US Patent No.Title
7344835 Methods for preventing inhibition of nucleic acid synthesis by pyrophosphate
4281061 Double antibody for enhanced sensitivity in immunoassay
4287300 Charge effects in enzyme immunoassays
4299916 Preferential signal production on a surface in immunoassays
4374925 Macromolecular environment control in specific receptor assays

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