Cataplexy

Cataplexy is a medical condition which often affects people who have narcolepsy, a disorder whose principal signsare EDS , sleep attacks, sleep paralysis, hypnagogic hallucinations and disturbed night-time sleep. Cataplexy is sometimes confused with epilepsy, where a series of flashes or other stimuli cause superficially similar seizures.The term cataplexy originates from the Greek kata, meaning down, and plexis, meaning a stroke or seizure. (From the Wikpedia article Cataplexy.)

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Recent Publications on Cataplexy:
Polymorphism located in TCRA locus confers susceptibility to essential hypersomnia with HLA-DRB1*1501-DQB1*0602 haplotype. Essential hypersomnia (EHS) exhibits excessive daytime sleepiness without...	21st November, 2009	Department of Human Genetics, Graduate School of Medicine, The University	J Hum Genet. 2009 Nov 20. DOI Direct Link
Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents. BACKGROUND: One underexploited property of anesthetics is their ability to...	17th November, 2009	Department of Neurology, Beth Israel Deaconess Medical Center, Harvard	Anesthesiology. 2009 Nov;111(5):1001-9. DOI Direct Link
Normalization of hypocretin-1 in narcolepsy after intravenous immunoglobulin treatment. OBJECTIVE: To investigate brain changes in both basal and cataplectic...	11th November, 2009	Service de Neurologie, 80, Avenue Augustin Fliche, Hopital	Neurology. 2009 Oct 20;73(16):1333-4. DOI Direct Link
A safety trial of sodium oxybate in patients with obstructive sleep apnea: Acute effects on sleep-disordered breathing. OBJECTIVE: Sodium oxybate (SXB) is an approved drug for the treatment of...	10th November, 2009	University of Western Ontario, London Health Sciences Centre, 375 South	Sleep Med. 2009 Nov 6. DOI Direct Link
REM-dreams recall in patients with narcolepsy-cataplexy. An abundant recall of dreams has been observed in clinical studies on...	10th November, 2009	Department of Psychology, University of Bologna, Viale Berti Pichat 5,	Brain Res Bull. 2009 Nov 6. DOI Direct Link
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Cataplexy Patents:
US Patent No.	Title
7141547	Albumin fusion proteins comprising GLP-1 polypeptides
7297817	Thio-substituted arylmethanesulfinyl derivatives
7323462	Morpholine dopamine agonists
7335640	Administration of hypocretin-1 for treatment of narcolepsy
7361667	4',4''-substituted 3.alpha.-(diphenylmethoxy) tropane analogs for treatment of mental disorders
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BioPortfolio Ltd. offers e-mail and postal lists for Cataplexy scientists - we have details of around 92 individuals working on Cataplexy .