Chorioamnionitis

Chorioamnionitis is an inflammatory condition of pregnancy affecting the uterus. According to a 2000 report by Dr Yvonne W. Wu, a pediatric neurologist at the University of California in San Francisco, chorioamnionitis is a risk factor for periventricular leukomalacia and cerebral palsy in newborns.The amniotic sac consists of two membranes: * The outer membrane, the chorion, contains the amnion and is part of the placenta. * The inner membrane, the amnion, contains the amniotic fluid and the fetus. Chorioamnionitis is an inflammation of the chorion and amnion. It is usually caused by a bacterial infection. (From the Wikpedia article Chorioamnionitis.)

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Recent Publications on Chorioamnionitis:
Fetal membranes as an interface between inflammation and metabolism: increased aquaporin 9 expression in the presence of spontaneous labor at term and chorioamnionitis. OBJECTIVE: Aquaporin 9 (AQP9) is a water channel protein characterized by...	18th November, 2009	Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan, USA.	J Matern Fetal Neonatal Med. 2009 Dec;22(12):1167-75.
Amniotic fluid soluble human leukocyte antigen-G in term and preterm parturition, and intra-amniotic infection/inflammation. OBJECTIVE: Circulating soluble human leukocyte antigen-G (sHLA-G) has been...	18th November, 2009	Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland, USA.	J Matern Fetal Neonatal Med. 2009 Dec;22(12):1151-66.
Differential expression pattern of genes encoding for anti-microbial peptides in the fetal membranes of patients with spontaneous preterm labor and intact membranes and those with preterm prelabor rupture of the membranes. OBJECTIVE: Increased amniotic fluid concentrations of anti-microbial...	18th November, 2009	Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan, USA.	J Matern Fetal Neonatal Med. 2009 Dec;22(12):1103-15.
Subclinical histologic chorioamnionitis and related clinical and laboratory parameters in preterm deliveries. BACKGROUND: Histologic chorioamnionitis (HCA) is associated with preterm...	17th November, 2009	Department of Pediatrics, Cathay General Hospital, Hsin Chu, Taiwan.	Pediatr Neonatol. 2009 Oct;50(5):217-21.
Factors affecting the duration of the latency period in preterm premature rupture of membranes. OBJECTIVE: To investigate the natural course of preterm premature rupture...	11th November, 2009	Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva,	J Matern Fetal Neonatal Med. 2009 Nov;22(11):1051-6.
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Chorioamnionitis Patents:
US Patent No.	Title
5869272	Methods for detection of gram negative bacteria
6255066	Bacterial vaginosis screening technique and a diagnostic kit for use therein
6346405	ARO1 multifunctional polypeptide of Candida albicans
6375970	Methods and materials for preterm birth prevention
6391047	Repair of ruptured membrane by injection of naturally occurring protein in amniotic fluid sac
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