Counterimmunoelectrophoresis

A laboratory technique used to evaluate the binding of an antibody to its antigen. Counterimmunoelectrophoresis is similar to immunodiffusion, but with the addition of an applied electrical field across the diffusion medium, usually an agar or polyacrylamide gel. The effect is rapid migration of the antibody and antigen out of their respective wells towards one another to form a line of precipitation, or a precipitin line, indicating binding. (From the Wikpedia article Counterimmunoelectrophoresis.)

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Recent Publications on Counterimmunoelectrophoresis:
Development and evaluation of an enzyme-linked immunosorbent assay based on recombinant VP2 capsids for the detection of antibodies to Aleutian mink disease virus. Aleutian disease (AD), a common infectious disease in farmed minks...	3rd November, 2009	Division of Microbiology and Epidemiology, Faculty of Veterinary Medicine,	Clin Vaccine Immunol. 2009 Sep;16(9):1360-5. Epub 2009 Jul 29. DOI Direct Link
[Prokaryotic expression and detective application of the main antigenic region of VP2 protein of Aleutian mink disease parvovirus] To research safer diagnosis antigen for ADV, the main antigenic region...	6th May, 2009	Key Laboratory of Wildlife Conservation, Northeast Forestry University,	Wei Sheng Wu Xue Bao. 2007 Dec 4;47(6):1088-90.
[Clinical cases in Medical Mycology. Case No. 36] Aleutian disease (AD), a common infectious disease in farmed minks...	4th March, 2009	Unidad Micologia, Hospital de Infecciosas Francisco Javier Muniz, Buenos	Rev Iberoam Micol. 2008 Dec 31;25(4):260-3.
Comparative qualitative and quantitative analysis of scleroderma (systemic sclerosis) serologic immunoassays. The heterogeneity of autoantibody specificities occurring in sera from...	17th December, 2008	Department of Pathophysiology, Medical School, National University of	J Autoimmun. 2008 Sep;31(2):166-74. Epub 2008 Aug 13. DOI Direct Link
Indirect immunofluorescence on HEp-2000 substrate is a sensitive method for detecting anti-Ro/SSA antibodies in patients with lupus erythematosus and/or photosensitivity. OBJECTIVE: To evaluate the sensitivity of indirect immunofluorescence...	17th December, 2008	Di.S.E.M. Section of Dermatology, University of Genoa, Genoa, Italy.	J Rheumatol. 2008 Jul;35(7):1320-2. Epub 2008 Jun 1.
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Counterimmunoelectrophoresis Patents:
US Patent No.	Title
5013664	Common protein of Haemophilus influenzae type b identified by a monoclonal antibody
5541291	Methods and compositions useful in the diagnosis and treatment of autoimmune diseases
5582984	Methods of use of phenanthridium DNA intercalators for fluorescence detection
5597572	Method of producing Neisseria meningitidis B vaccine, and vaccine produced by method
5599932	Intercalators having affinity for DNA and methods of use
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