Recent Publications on Dcmp Deaminase: |  |
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.
1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine [HPMP-5-azaC],...
Direct Link | 9th September, 2008
| Rega Institute for Medical Research, Katholieke Universiteit Leuven,
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Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+.
2'-Deoxycytidylate deaminase [or deoxycytidine-5'-monophosphate (dCMP)...
Direct Link | 25th March, 2008
| Beijing Synchrotron Radiation Facility, Institute of High Energy Physics,
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Involvement of deoxycytidylate deaminase in the response to S(n)1-type methylation DNA damage in budding yeast.
2''-Deoxycytidylate deaminase [or deoxycytidine-5''-monophosphate (dCMP)...
Direct Link | 9th January, 2008
| Molecular and Medical Genetics, Oregon Health & Science University,
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An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients.
PURPOSE: We examined the pattern of single-nucleotide polymorphisms (SNPs)...
Direct Link | 21st September, 2007
| Cancer Metastasis Research Center, Yonsei Cancer Center, Yonsei University
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Chloroviruses encode a bifunctional dCMP-dCTP deaminase that produces two key intermediates in dTTP formation.
The chlorovirus PBCV-1, like many large double-stranded DNA-containing...
Direct Link | 15th September, 2007
| Department of Plant Pathology, University of Nebraska-Lincoln, Lincoln, NE
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p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage.
Human fibroblasts in culture obtain deoxynucleotides by de novo...
Direct Link | 11th July, 2007
| Department of Biology, University of Padova, I-35131 Padova, Italy.
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Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics.
PURPOSE: Gemcitabine is a nucleoside analogue with activity against solid...
Direct Link | 9th December, 2006
| Department of Molecular Pharmacology and Experimental Therapeutics, Mayo
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Ribonucleotide reductase M1 (RRM1) 2464G>A polymorphism shows an association with gemcitabine chemosensitivity in cancer cell lines.
OBJECTIVES: Significant variability in the efficacy and toxicity of an...
Direct Link | 3rd November, 2006
| Cancer Metastasis Research Center, Yonsei Cancer Center, Yonsei University
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[Special function of deoxycytidine kinase (dCK) in the activation of chemotherapeutic nucleoside analogs and in the inhibition of cell proliferation]
Deoxycytidine kinase (dCK) plays a central role in the deoxynucleoside...
Direct Link | 12th May, 2005
| Orvosi Vegytani, Molekularis Biologiai es Pathobiokemiai Intezet,
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Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase.
2'-Deoxycytidylate deaminase (dCD) converts deoxycytidine 5'-monophosphate...
Direct Link | 16th December, 2004
| Wadsworth Center, New York State Department of Health, Albany, New York
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An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines.
The mechanisms of resistance to the antimetabolite gemcitabine in...
Direct Link | 28th July, 2004
| Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana,
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| Identification of novel cellular targets in biliary tract cancers using global gene expression technology.
| 4th September, 2003
| Department of Pathology, The Johns Hopkins University School of Medicine,
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| Human cytomegalovirus requires cellular deoxycytidylate deaminase for replication in quiescent cells.
| 2nd July, 2003
| Department of Public Health and Microbiology, University of Torino, Via
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| Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase.
| 10th January, 2003
| Department of Pharmacology, Yale University School of Medicine, New Haven,
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