Dealkylation

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Recent Publications on Dealkylation:
N-Dealkylation of aliphatic amines and selective synthesis of monoalkylated aryl amines. Highly selective alkyl transfer processes of mono-, di- and trialkyl...	3rd July, 2008	Leibniz-Institut fur Katalyse e.V. an der Universitat Rostock,	Chem Commun (Camb). 2008 Jul 21;(27):3199-201. Epub 2008 May 8. DOI Direct Link
Postmenstrual age and CYP2D6 polymorphisms determine tramadol o-demethylation in critically ill neonates and infants. To document determinants of O-demethylation in critically ill (pre)term...	27th June, 2008	Neonatal Intensive Care Unit, University Hospitals, campus Gasthuisberg,	Pediatr Res. 2008 Jun;63(6):674-9. DOI Direct Link
Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials. The disposition of three 4-aminoquinoline leads, namely isoquine (ISO),...	20th June, 2008	Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Drug Discovery, 1250	J Pharm Sci. 2008 Jun 18;. DOI Direct Link
Hypercalcemia of Primary Hyperparathyroidism was Treated by Cinacalcet in a Patient with Liver Cirrhosis. Cinacalcet is a type II calcimimetic agent which is an allosteric...	19th June, 2008	1Division of Endocrinology and Metabolism, Department of Internal	Exp Clin Endocrinol Diabetes. 2008 Jun 17;. DOI Direct Link
IDENTIFICATION OF THE HUMAN ENZYMES INVOLVED IN THE OXIDATIVE METABOLISM OF DASATINIB. AN EFFECTIVE APPROACH FOR DETERMINING METABOLITE FORMATION KINETICS. Dasatinib (SPRYCEL((R)), BMS-354825) is a potent protein kinases inhibitor...	17th June, 2008	Bristol-Myers squibb.	Drug Metab Dispos. 2008 Jun 12;. DOI Direct Link
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Dealkylation Patents:
US Patent No.	Title
7312562	Heterodiamondoid-containing field emission devices
7332638	Process for the production of triptane
7335295	Coated zeolite catalysts and use for hydrocarbon conversion
7335753	Bifunctional heterocyclic compounds and methods of making and using same
7339060	Preparation of cabergoline
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