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Delirium

Delirium is an acute and relatively sudden decline in attention-focus, perception, and cognition. In medical usage it is not synonymous with drowsiness, and may occur without it. It is commonly associated with a disturbance of consciousness . The change in cognition or the development of a perceptual disturbance, must be one that is not better accounted for by a preexisting, established, or evolving dementia. Usually the rapidly fluctuating time course of delirium is used to help in the latter distinction.Because it represents a change in cognitive function, the diagnosis cannot be made without knowledge of the affected person's baseline level of cognitive function.Without careful assessment, delirium can easily be confused with a number of psychiatric disorders because many of the signs and symptoms are conditions present in dementia, depression, and psychosis. Delirium is probably the single most common acute disorder affecting adults in general hospitals. It affects 10-20% of all hospitalized adults, and 30-40% of elderly hospitalized patients.Delirium itself is not a disease, but rather a clinical syndrome , which result from an underlying disease or new problem with mentation. Like its components , delirium is simply the common symptomatic manifestation of early brain or mental dysfunction .Distressing symptoms of delirium are sometimes treated with antipsychotics, preferably those with minimal anticholinergic activity, such as haloperidol or risperidone, or else with benzodiazepines, which decrease the anxiety felt by a person who may also be disoriented, and has difficulty completing tasks. However, since these drug treatments do not address the underlying cause of delirium, and may mask changes in delirium which themselves may be helpful in assessing the patient's underlying changes in health, their use is difficult. Because delirium is a mere symptom of another problem which may be very subtle, the wisdom of treatment of the delirious patient with drugs must overcome natural skepticism, and requires a high degree of skill. (From the Wikpedia article Delirium.)

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Recent Publications on Delirium:

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[Clinical potentialities and perspectives for the use of aripiprazole in other disorders than its classical indications.]
Aripiprazole is indicated for the treatment of schizophrenia in Europe and...
4th July, 2008
Service de psychiatrie de l'adolescent, centre hospitalier, B.P. 29, 68250 Encephale. 2008 Apr;34(2):187-93. Epub 2008 Mar 5.
DOI Direct Link
Prevalence and comorbidity of neuropsychiatric symptoms in Alzheimer's disease.
Introduction. The objective of this study is to describe the frequency and...
4th July, 2008
Actas Esp Psiquiatr. 2008 Jul 2;.
Delirium associated with lamotrigine and fluoxetine treatment.
Introduction. The objective of this study is to describe the frequency and...
3rd July, 2008
The authors report no competing interests. Am J Psychiatry. 2008 Jul;165(7):918-9.
DOI Direct Link
Postoperative delirium.
Introduction. The objective of this study is to describe the frequency and...
3rd July, 2008
Massachusetts General Hospital, Department of Psychiatry, Warren 615, 55 Am J Psychiatry. 2008 Jul;165(7):803-12.
DOI Direct Link
Incidence and predictors of post-cardiotomy delirium.
OBJECTIVE: To determine the incidence and predictors of delirium after...
2nd July, 2008
Makati Medical Center, Manila, Philippines. Am J Geriatr Psychiatry. 2008 Jul;16(7):575-83.
DOI Direct Link

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BioNews Results for Delirium:

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New Reductions in CMS Payments Shine Spotlight on
Pharmacy Practice News:  Jul 3 2008 4:02AM Matching: delirium
Roche Introduces Program to Facilitate Corporate Pandemic Stockpiling of Tamiflu(R)
KOTA Territory News:  Jun 27 2008 12:04AM Matching: delirium
Roche Introduces Program to Facilitate Corporate Pandemic Stockpiling of Tamiflu(R)
PR Newswire via Yahoo!:  Jun 26 2008 7:04PM Matching: delirium
Roche Introduces Program to Facilitate Corporate Pandemic Stockpiling of Tamiflu(R)
Business Journal of Milwaukee:  Jun 26 2008 5:49PM Matching: delirium
Roche Introduces Program to Facilitate Corporate Pandemic Stockpiling of Tamiflu(R)
Columbus Business First:  Jun 26 2008 5:46PM Matching: delirium
Promote your company here: BioNewsCast - Press Release Distribution

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Delirium Clinical Trials:

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Trial of Safety Nets In Hospitalized Patients
Delirium;   Agitated Behavior;   Alcohol Withdrawl;   Acute Confusional State;   Acute Psychosis
Postanesthesia Cognitive Recovery and Neuropsychologic Complications
Anesthesia Recovery Period;   Delirium, Dementia, Cognitive Disorders;   Neurobehavioural Manifestation;   Mental Competency
The BRAIN ICU Study: Bringing to Light the Risk Factors
Delirium;   Cognition Disorders;   Dementia
Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic
Cognitive/Functional Effects;   Delirium;   Esophageal Cancer;   Head and Neck Cancer;   Lung Cancer
Prevention of Postoperative Delirium With Donepezil
Cognitively Normal Elderly Individuals

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Delirium Patents:

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US Patent No.Title
7285218 Method for the extra-corporeal qualitative and/or quantitative recording of neurotoxic substances in the blood plasma of an individual
7320979 N-[(piperazinyl)hetaryl]arylsulfonamide compounds
7321862 System and method for patient-worn monitoring of patients in geographically dispersed health care locations
7326721 Doxepin analogs and methods of use thereof
7326781 Polynucleotides encoding the human citron kinase polypeptide, BMSNKC.sub.--0020/0021

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BioPortfolio Ltd. offers e-mail and postal lists for Delirium scientists - we have details of around 1513 individuals working on Delirium .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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