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Dysmenorrhea

Dysmenorrhea , cramps or painful menstruation, involves menstrual periods that are accompanied by either sharp, intermittent pain or dull, aching pain, usually in the calves, pelvis or lower abdomen. Many young swimmers experience menstrual cramps due to their body structure. The body structure is unable to be altered. Side effects may include nausea, headaches, or extreme pain within the next couple days. Main causes are due to the body structure, deep water, and extreme coldness; this will also cause the person to be inflexible.Painful menstruation affects approximately 50% of menstruating women, and 10% are incapacitated for up to 3 days. Painful menstruation is the leading cause of lost time from school and work among women of childbearing age. This pain may precede menstruation by several days or may accompany it, and it usually subsides as menstruation tapers off.Although some pain during menstruation is normal, excessive pain is not. Dysmenorrhea refers to menstrual pain severe enough to limit normal activities or require medication. It may coexist with excessively heavy blood loss .*Primary dysmenorrhea refers to menstrual pain that occurs in otherwise healthy women . This type of pain is not related to any specific problems with the uterus or other pelvic organs. *Secondary dysmenorrhea is menstrual pain that is attributed to some underlying disease process or structural abnormality either within or outside the uterus . Endometriosis is the most common cause of dysmenorrhea associated with a disease process and is frequently misdiagnosed. The incidence of menstrual pain is greatest in women in their late teens and 20s, then declines with age. Some women experience increased menstrual pain in their late 30s and 40s as their endocrine systems prepare for menopause by decreasing hormone levels and thus fertility. It does not appear to be affected by childbearing. An estimated 10 percent to 15 percent of women experience monthly menstrual pain severe enough to prevent normal daily function at school, work, or home. (From the Wikpedia article Dysmenorrhea.)

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Recent Publications on Dysmenorrhea:

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Efficacy of Gonadotropin-Releasing Hormone Agonist and an Extended-Interval Dosing Regimen in the Treatment of Patients with Adenomyosis and Endometriosis.
Aims: To determine the effects of gonadotropin-releasing hormone agonist...
20th November, 2009
Department of Obstetrics and Gynecology, First Municipal Hospital Gynecol Obstet Invest. 2009 Nov 17;69(2):73-77.
DOI Direct Link
Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis.
ABSTRACT: Objetive: Thrombospondin-1 serum levels is correlate with pelvic...
18th November, 2009
J Ovarian Res. 2009 Nov 16;2(1):18.
DOI Direct Link
Endometriosis in Italy: from cost estimates to new medical treatment.
Endometriosis is defined as the presence of endometrial-like tissue...
17th November, 2009
Division of Obstetrics and Gynecology, Department of Pediatrics, Gynecol Endocrinol. 2009 Nov;25(11):734-40.
Effect of peritoneal fluid from endometriosis patients on neuroblastoma cells in culture.
AIM: Endometriosis is often associated with lower abdominal pain,...
17th November, 2009
Department of Obstetrics/Gynaecology, University of Berne, Berne, Gynecol Endocrinol. 2009 Nov;25(11):707-12.
[Clinical practice guidelines. Diagnosis and treatment of primary dysmenorrhea in teenagers]
AIM: Endometriosis is often associated with lower abdominal pain,...
12th November, 2009
Clinica para la Atencion de la Paciente Adolescente del Instituto Nacional Ginecol Obstet Mex. 2009 Aug;77(8):S211-29.

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Press Releases About Dysmenorrhea:

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Biostar Pharmaceuticals, Inc. Announces Record Third Quarter 2009 Financial Results 12th November, 2009 Biostar Pharmaceuticals, Inc.
XIANYANG, China, Nov. 12 /PRNewswire-Asia-FirstCall/ -- Biostar Pharmaceuticals, Inc. (OTC Bulletin Board: BSPM) ("Biostar" or "the Company"), a Xianyang-based developer,
Neurocrine Announces Top-Line Results From 702 Study (Lilac PETAL Study) of Elagolix for Treatment of Endometriosis Pain 25th March, 2009 Neurocrine Biosciences, Inc.
STUDY CONFIRMS EFFICACY IN VALIDATED ENDPOINTS; MIXED RESULTS IN EXPLORATORY ENDPOINTS COMPANY TO HOST CONFERENCE CALL AND WEBCAST THURSDAY, MARCH 26TH AT 8:00AM ET / 5:00AM PT SAN DIEGO, March 25
Neurocrine Biosciences Announces Successful Elagolix PETAL Study in Endometriosis 2nd September, 2008 Neurocrine Biosciences, Inc.
SAN DIEGO, Sept. 2 /PRNewswire-FirstCall/ -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced positive safety and efficacy results from its third Phase II clinical trial using its
Neurocrine Biosciences Reports Second Quarter 2008 Results 30th July, 2008 Neurocrine Biosciences, Inc.
SAN DIEGO, July 30 /PRNewswire-FirstCall/ -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced its financial results for the quarter ended June 30, 2008. For the second quarter of 2008,

BioNews Results for Dysmenorrhea:

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Biostar Pharmaceuticals, Inc. Announces Record Third Quarter 2009 Financial Results
Entrepreneur.com:  Nov 13 2009 7:39PM Matching: dysmenorrhea
Biostar Pharmaceuticals, Inc. Announces Record Third Quarter 2009 Financial Results
Therapeutics Daily:  Nov 12 2009 2:49PM Matching: dysmenorrhea
Biostar Pharmaceuticals reports financial results for the third quarter of 2009
News-Medical.Net:  Nov 12 2009 2:46PM Matching: dysmenorrhea
Biostar Pharmaceuticals, Inc. Announces Record Third Quarter 2009 Financial Results
Street Insider:  Nov 12 2009 1:34PM Matching: dysmenorrhea
Biostar Pharmaceuticals, Inc. Announces Record Third Quarter 2009 Financial Results
Yahoo! Canada:  Nov 12 2009 1:13PM Matching: dysmenorrhea
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Dysmenorrhea Patents:

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US Patent No.Title
7534914 Substituted methyl aryl or heteroaryl amide compounds
7563797 Substituted imidazo(1,2-A)pyrimidines and imidazo(1,2-A) pyridines as cannabinoid receptor ligands
7566739 Substituted N-sulfonylaminophenylethyl-2-phenoxyacetamide compounds as VR1 receptor antagonists
7569364 Anti-NGF antibodies and methods using same
7569384 Albumin fusion proteins

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Companies working in the area of Dysmenorrhea from Bioportfolio's Biocorporate database :

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Company Name

Metris Therapeutics

Established in 1996, Metris now has several products in development. These are a treatment for endometriosis, a treatment for menorrhagia / dysmenorrhea, using a proprietary vaginal drug delivery...
www.metris.co.uk/        View full profile
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Pharma-G Incorporated

Pharma-G inc is an early stage development Company that has developped a novel proprietary drug discovery technology allowing it to design drug candidates using G protein coupled receptor as...
        View full profile

BioPortfolio Ltd. offers e-mail and postal lists for Dysmenorrhea scientists - we have details of around 346 individuals working on Dysmenorrhea .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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