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Dyspareunia

Dyspareunia is painful sexual intercourse, due to medical or psychological causes. The term is used almost exclusively in women, although the problem can also occur in men. The causes are often reversible, even when long-standing, but self-perpetuating pain is a factor after the original cause has been removed.Dyspareunia is considered to be primarily a physical, rather than an emotional, problem until proven otherwise. In most instances of dyspareunia, there is an original physical cause. Extreme forms, in which the woman's pelvic floor musculature contracts involuntarily, is termed vaginismus.According to DSM-IV , the diagnosis of dyspareunia is made when the patient complains of recurrent or persistent genital pain before, during, or after sexual intercourse that is not caused exclusively by lack of lubrication or by vaginismus. Clinically, it is often difficult to separate dyspareunia from vaginismus, since vaginismus may occur secondary to a history of dyspareunia and even mild vaginismus is often accompanied by dyspareunia. It is important to establish whether the dyspareunia is acquired or lifelong and whether it is generalized or situational. Further inquiry should determine whether the pain is superficial or deep - whether it occurs primarily at the vaginal outlet or vaginal barrel or upon deep thrusting against the cervix. Even when the pain can be reproduced during a physical examination, the possible role of psychological factors in either causing or maintaining the pain must be acknowledged and dealt with in treatment. (From the Wikpedia article Dyspareunia.)

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Recent Publications on Dyspareunia:

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Impact of endometriosis on quality of life: A pilot study.
Endometriosis affects 6-10% of women in reproductive age, 35-50% of whom...
12th November, 2009
Department of Obstetrics and Gynecology, Justus Liebig University of Gynecol Endocrinol. 2009 Nov;25(11):722-5.
[How to diagnose and how to treat diseases of the genital mucosa?]
The genital area in women is covered by a keratinized squamous stratified...
11th November, 2009
Clinique de Pathologie des Muqueuses, Hopital Erasme, Bruxelles. Rev Med Brux. 2009 Sep;30(4):385-91.
[Sexological problems in neurological disorders: neurosexology]
The author has examined this complex subject-matter as he has not found...
10th November, 2009
Ideggyogy Sz. 2009 Sep 30;62(9-10):292-7.
Congenital urethrovaginal fistula with imperforate hymen: a first case report.
BACKGROUND: Congenital urethrovaginal fistulas are rare, and all five...
30th October, 2009
Department of Urology, King Edward Memorial Hospital, Mumbai, India. J Obstet Gynaecol Can. 2009 Jul;31(7):652-3.
Successful treatment of orgasmic dysfunction using specialized physical therapy: a case report.
BACKGROUND: Sexual dysfunction in women is a challenging and difficult...
29th October, 2009
Department of Obstetrics and Gynecology, University of Connecticut, J Reprod Med. 2009 Aug;54(8):520-2.

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Dyspareunia Clinical Trials:

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Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women

Dyspareunia Patents:

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US Patent No.Title
7402687 Dihydrobenzofuran derivatives and uses thereof
7449595 Nitrosated and nitrosylated prostaglandins, compositions and methods of use
7452875 Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
7456184 Melanocortin receptor-specific compounds
7459531 50 Human secreted proteins

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Companies working in the area of Dyspareunia from Bioportfolio's Biocorporate database :

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Company Name

Urigen Holdings Inc

Urigen is a specialty pharmaceutical company dedicated to the development and commercialization of therapeutic products for urological disorders. Urigen has five products in development for urology...
www.urigen.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Dyspareunia scientists - we have details of around 196 individuals working on Dyspareunia .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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