Eif-2 Kinase

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Recent Publications on Eif-2 Kinase:
Semaphorin controls epidermal morphogenesis by stimulating mRNA translation via eIF2alpha in Caenorhabditis elegans. Conserved semaphorin-plexin signaling systems govern various aspects of...	4th July, 2008	Division of Biological Science, Nagoya University Graduate School of	Genes Dev. 2008 Apr 15;22(8):1025-36. DOI Direct Link
Microarray analysis of thapsigargin-induced stress to the endoplasmic reticulum of mouse osteoblasts. Activating transcription factor 4 (ATF4) protein has a dual role in...	2nd July, 2008	Department of Biomedical Engineering, Indiana University-Purdue	J Bone Miner Metab. 2008;26(3):231-40. Epub 2008 May 11. DOI Direct Link
The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells. N-(4-hydroxyphenyl)retinamide (4HPR) is a synthetic retinoid that has been...	20th June, 2008	Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong	Exp Cell Res. 2008 May 1;314(8):1667-82. Epub 2008 Mar 14. DOI Direct Link
Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner. The human interferon-induced protein kinase PKR is a key component of...	17th June, 2008	Department of Chemistry, The Pennsylvania State University, University	RNA. 2008 Jun;14(6):1201-13. Epub 2008 Apr 21. DOI Direct Link
Untangling the unfolded protein response. Resistance to current cancer therapies has forced scientists to...	17th June, 2008	Section of Haemato-Oncology, The Institute of Cancer Research, Sutton,	Cell Cycle. 2008 Apr;7(7):865-9. Epub 2008 Jan 9.
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Eif-2 Kinase Patents:
US Patent No.	Title
7198929	14790, a novel protein kinase molecule and uses therefor
6864078	14790, novel protein kinase molecule and uses therefor
5888796	Clone of a nucleotide sequence encoding a protein having two functions
5885820	Clone of a nucleotide sequence encoding a protein having two functions
5670330	Anti-tumor agent assay using PKR
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