Electrophoresis

For specific types of electrophoresis , see electrophoresis .Electrophoresis is the most known electrokinetic phenomena. It was discovered by Reuss in 1809 . He observed that clay particles dispersed in water migrate under influence of an applied electric field. There are detailed descriptions of Electrophoresis in many books on Colloid and Interface Science, , ,,, . There is an IUPAC Technical Report prepared by a group of most known world experts on the electrokinetic phenomena. :Generally, electrophoresis is the motion of dispersed particles relative to a fluid under the influence of an electric field that is space uniform. Alternatively, similar motion in a space non-uniform electric field is called dielectrophoresis. Electrophoresis occurs because particles dispersed in a fluid almost always carry an electric surface charge. An electric field exerts electrostatic Coulomb force on the particles through these charges.Another force is electrostatic as well. It is known from double layer theory that all surface charges in fluids are screened with a diffuse layer. This diffuse layer has the same absolute charge value, but with opposite sign from the surface charge. The electric field induces force on the diffuse layer, as well as on the surface charge. The total value of this force equals to the first mentioned force, but it is oppositely directed. However, only part of this force is applied to the particle. It is actually applied to the ions in the diffuse layer. These ions are at some distance from the particle surface. They transfer part of this electrostatic force to the particle surface through viscous stress. This part of the force that is applied to the particle body is called electrophoretic retardation force. There is one more electric force, which is associated with deviation of the double layer from spherical symmetry and surface conductivity due to the excees ions in the diffuse layer. This force is called the electrophoretic relaxation force All these forces are balanced with hydrodynamic friction, which affects all bodies moving in viscous fluids with low Reynolds number. The speed of this motion v is proportional to the electric field strength E if the field is not too strong. Using this assumption makes possible the introduction of electrophoretic mobility μ_e as coefficient of proprtionality between particle speed and electric field strength: :$mu\_e\; =$Multiple theories were developed during 20th century for calculating this parameter. Ref. 1 provides an overview. Here are some of the most general conclusions. (From the Wikpedia article Electrophoresis.)

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Recent Publications on Electrophoresis:
Metal cations for the determination of fluorescent phosphoinositides by capillary electrophoresis. Phosphatidylinositol (PI) and its phosphorylated derivatives known as...	15th November, 2008	Department of Chemistry, Kent State University, Kent, OH, USA. Fax:	J Sep Sci. 2008 Nov 13. DOI Direct Link
Identification of Hsc70 as target for AGE modification in senescent human fibroblasts. Cellular senescence is known as a potent mechanism of tumor suppression,...	15th November, 2008	Institute for Biomedical Aging Research, Austrian Academy of Sciences,	Biogerontology. 2008 Nov 14. DOI Direct Link
Integration of the barley genetic and seed proteome maps for chromosome 1H, 2H, 3H, 5H and 7H. Two-dimensional gel electrophoresis was used to screen spring barley...	15th November, 2008	Carlsberg Laboratory, Gamle Carlsberg Vej 10, 2500, Valby, Denmark.	Funct Integr Genomics. 2008 Nov 14. DOI Direct Link
Proteomics study of the hepatitis C virus replication complex. RNA replication of HCV occurs in the multiprotein complexes associated...	15th November, 2008	Department of Microbiology, Immunology and Molecular Genetics University	Methods Mol Biol. 2009;510:185-93. DOI Direct Link
[Isoenzymatic characterization of human isolates of Leishmania sp (Kinetoplastida: Trypanosomatidae) from the municipalities of Rio Preto da Eva and Manaus, State of Amazonas.] Twenty-three isolates of Leishmania sp from patients in the municipalities...	15th November, 2008	Laboratorio de Leishmaniose e Doenca de Chagas, Instituto Nacional de	Rev Soc Bras Med Trop. 2008 Sep-Oct;41(5):512-4.
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BioNews Results for Electrophoresis:
Examine the Biomarkers: The Expanding Global Market	Forbes.com:  Nov 13 2008 10:56AM Matching: electrophoresis
Examine the Biomarkers: The Expanding Global Market	Business Wire via Yahoo!:  Nov 13 2008 10:37AM Matching: electrophoresis
World Market for Biotechnology Reagents to Reach $32.5 Billion by 2012, According to New Report by Global Indu	Yahoo!:  Nov 13 2008 12:17PM Matching: electrophoresis
Newcastle gets new proteomics facility	Pharma Times:  Nov 13 2008 10:24AM Matching: electrophoresis
New UK bioscience facility launched	Pharma Live:  Nov 10 2008 10:15PM Matching: electrophoresis
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Electrophoresis Clinical Trials:
Statins and the Urinary Proteome	Statin Induced Proteinuria

Electrophoresis Patents:
US Patent No.	Title
7449303	Use of JAG2 expression in diagnosis of plasma cell disorders
7449443	Method for stabilization of proteins using non-natural amino acids
7449450	Compounds, methods of screening, and in vitro and in vivo uses involving anti-apoptotic genes and anti-apoptotic gene products
7449456	Diaminopyrimidinecarboxamide derivative
7449477	7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)
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Companies working in the area of Electrophoresis from Bioportfolio's Biocorporate database :
Company Name
Advanced American Biotechnology Advanced American Biotechnology & Imaging providing software and hardware for electrophoresis, TLC, image analysis, gel documentation and densitometry... www.aabi.com/        View full profile
Affinity Sensors Affinity Sensors is a division of the Thermo BioAnalysis Corporation. Thermo BioAnalysis designs, manufactures and markets instruments and information management systems for use in biochemical... www.affinity-sensors.com/        View full profile
Bio-Rad Laboratories Incorporated Bio-Rad Laboratories has remained at the center of scientific discovery for more than 40 years by providing a broad range of innovative tools and services to the clinical diagnostics and...         View full profile
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